Compartment diversity in innate immune reprogramming

Publication date: Available online 27 December 2017
Source:Microbes and Infection
Author(s): Orhan Rasid, Jean-Marc Cavaillon
Pathogens or endogenous molecules can reprogram innate immunity. This process can take the form of priming or tolerance depending on the activating signal, and favors enhanced resistance of infection and other insults, by modulating inflammation. Similarly to their organ-specific properties, reprogramming of macrophages and NK cells, is also compartmentalized.



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