Regulatory T Cells Know What Is Needed to Regenerate

Publication date: 18 December 2017
Source:Developmental Cell, Volume 43, Issue 6
Author(s): Christopher Jahn, Gilbert Weidinger
Adaptive immunity has been suggested to limit regeneration in mammals. However, in this issue of Developmental Cell, Hui et al. (2017) report that regulatory T cells are required for regeneration of heart, spinal cord, and retina in the zebrafish. Intriguingly, in each organ system, Treg cells secrete organ-specific regeneration factors.

Teaser

Adaptive immunity has been suggested to limit regeneration in mammals. However, in this issue of Developmental Cell, Hui et al. (2017) report that regulatory T cells are required for regeneration of heart, spinal cord, and retina in the zebrafish. Intriguingly, in each organ system, Treg cells secrete organ-specific regeneration factors.


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