Comparing mutational profiles between cell-free circulating tumor DNA and tumor DNA in laryngeal carcinoma patients
H McMullen, A Greer, AR Khandelwal, H Mickie, X Ma… - 2017
Introduction: The incidence of laryngeal cancers is on the rise with an estimated 12,000 new
cases diagnosed each year in the United States. Despite advancements in surgery,
chemotherapy, radiotherapy, and targeted therapy, the prognosis for advanced laryngeal
cases diagnosed each year in the United States. Despite advancements in surgery,
chemotherapy, radiotherapy, and targeted therapy, the prognosis for advanced laryngeal
Optimizing patient selection for total laryngectomy versus larynx-preservation chemoradiotherapy for locally advanced laryngeal squamous cell carcinoma: An …
SA Patel, MM Qureshi, K Mak, NJ Giacalone, S Jalisi… - 2017
Purpose: The decline in survival of patients diagnosed with laryngeal cancer over the past
two decades has been associated with a rise in nonsurgical management for stage III/IV
disease following results from the VA Larynx Trial and RTOG 91-11. To clarify the potential
two decades has been associated with a rise in nonsurgical management for stage III/IV
disease following results from the VA Larynx Trial and RTOG 91-11. To clarify the potential
[HTML] The tissue distribution and significance of B7-H4 in laryngeal carcinoma
L Chen, M Jin, C Li, Y Shang, Q Zhang - Oncotarget, 2017
Abstract The costimulatory signals CD28 and B7 have been shown to control tumor invasion
and metastasis by regulating T cell activation, whereas the distribution characteristics of B7-
associated proteins in laryngeal carcinoma (LC) tissue are still unclear. Here, the expression
and metastasis by regulating T cell activation, whereas the distribution characteristics of B7-
associated proteins in laryngeal carcinoma (LC) tissue are still unclear. Here, the expression
The impact of iatrogenic glottic atresia due to photodynamic therapy for laryngeal cancer: A report of two cases
S Hosokawa, S Takebayashi, H Mineta - Photodiagnosis and Photodynamic Therapy, 2017
Abstract Photodynamic therapy (PDT) is a minimally invasive therapy used in the treatment
of premalignant and malignant diseases, including head and neck carcinomas. It can be
applied before or after chemotherapy, irradiation, or surgery. Unlike irradiation and surgery,
of premalignant and malignant diseases, including head and neck carcinomas. It can be
applied before or after chemotherapy, irradiation, or surgery. Unlike irradiation and surgery,
Continuous intraoperative recurrent laryngeal nerve monitoring during thyroid surgery. The Greek experience
S Karakozis, M Karageorgou, N Alexandrou… - European Journal of …, 2017
Methods: Bilateral vagus nerve continuous monitoring was used to all patients who
underwent thyroid surgery. The guidelines of the international neuromonitoring study group
were followed closely. The effects of continuous neuromonitoring technique during the
underwent thyroid surgery. The guidelines of the international neuromonitoring study group
were followed closely. The effects of continuous neuromonitoring technique during the
Association of quantitative metastatic lymph node burden with survival in hypopharyngeal and laryngeal cancer
AS Ho, S Kim, M Tighiouart, C Gudino, A Mita… - JAMA Oncology, 2017
Importance Nodal staging for laryngohypopharyngeal cancers is based primarily on size
and laterality, with less value placed on absolute number of metastatic lymph nodes (LNs).
We are aware of no studies to date that have specifically addressed the prognostic effect of
and laterality, with less value placed on absolute number of metastatic lymph nodes (LNs).
We are aware of no studies to date that have specifically addressed the prognostic effect of
Overexpressed miR-128a enhances chemoradiotherapy to laryngeal cancer cells and its correlation with BMI1
H Chen, L Jin, L Zhou, J Huang - 2017
Aim: To clarify the function of miR-128a on radiotherapy and chemotherapy resistance in
laryngeal cancer and explore the possible mechanism. Materials & methods: Hep-2 and
AMC-HN-8 cell lines were cultured. MiR-128a was upregulated utilizing lentiviral
laryngeal cancer and explore the possible mechanism. Materials & methods: Hep-2 and
AMC-HN-8 cell lines were cultured. MiR-128a was upregulated utilizing lentiviral
[HTML] Roles of KAI1 and nm23 in lymphangiogenesis and lymph metastasis of laryngeal squamous cell carcinoma
Z Zheng, R Tian, P Wang - World Journal of Surgical Oncology, 2017
Lymphatic metastasis contributes to the poor prognosis of laryngeal squamous cell
carcinoma (LSCC). This study aimed to investigate the roles of two metastasis suppressor
genes, KAI1 and nm23, in lymphangiogenesis and lymph metastasis of LSCC. A total of 45
carcinoma (LSCC). This study aimed to investigate the roles of two metastasis suppressor
genes, KAI1 and nm23, in lymphangiogenesis and lymph metastasis of LSCC. A total of 45
[PDF] Horizontal Vertical Laryngectomy in Transglottic Laryngeal Cancer
N Başerer - 2017
Abstract Organ preservation surgery in the larynx cancer started with cordectomy technique
in 1850s. Leading laryngologists have described alternative techniques to total
laryngectomy (TL). But the extent of their indications, resection limits and reconstruction
in 1850s. Leading laryngologists have described alternative techniques to total
laryngectomy (TL). But the extent of their indications, resection limits and reconstruction
Metastatic Laryngeal Large Cell Neuroendocrine Carcinoma: A Rare Case of Presentation and Extreme Tumor Burden
A Dunn, BG Broadfoot, J Hunt, JR Kaley, O Atiq… - Journal of Cutaneous Pathology
ABSTRACT Large cell neuroendocrine carcinoma (LCNEC) of the larynx is an aggressive
form of neuroendocrine carcinoma that affects smokers at an average age of 60 years.
LCNEC is characterized by large cells with round to ovoid nuclei distributed in a trabecular
form of neuroendocrine carcinoma that affects smokers at an average age of 60 years.
LCNEC is characterized by large cells with round to ovoid nuclei distributed in a trabecular
[PDF] English obstruents and laryngeal markedness
P Szigetvári
Descriptions of English list four types of two-member obstruent clusters with regard to their
laryngeal specification: fortis+ fortis (eg actor), fortis+ lenis (eg anecdote), lenis+ fortis (eg
Aztec), and lenis+ lenis (eg wisdom). The first type, ff, is most frequent and free in its
laryngeal specification: fortis+ fortis (eg actor), fortis+ lenis (eg anecdote), lenis+ fortis (eg
Aztec), and lenis+ lenis (eg wisdom). The first type, ff, is most frequent and free in its
[PDF] The role of laryngeal cues in the perception of Hungarian fricatives in voicing assimilation
Z Bárkányi, ZG Kiss
The present paper reports a pilot study that aims to investigate the perceptual cues
associated with the laryngeal contrast in Hungarian sibilant fricatives. The study is based on
the results of a phoneme-identification experiment that investigated how native speakers of
associated with the laryngeal contrast in Hungarian sibilant fricatives. The study is based on
the results of a phoneme-identification experiment that investigated how native speakers of
Laryngeal chondronecrosis after radiation therapy in a dog
J Bertran, M Martinez, M Breit, MA McLoughlin, KL Ham… - Journal of Small Animal Practice
Abstract A 5-year-old pug presented with a soft tissue swelling on the ventral neck and
moderate stridor with associated respiratory effort. This patient received hypofractionated
radiotherapy for metastatic upper lip mast cell tumour and to the submandibular lymph
moderate stridor with associated respiratory effort. This patient received hypofractionated
radiotherapy for metastatic upper lip mast cell tumour and to the submandibular lymph
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