Significance of 18F-sodium fluoride positron emission tomography in characterization of POEMS osteosclerotic lesions better than 18F-fluorodeoxyglucose positron emission tomography

Fahad Abdul Rehman Marafi, Rashid Rasheed, Sharjeel Usmani, Fareeda Alkandari, Anam Iqbal

Indian Journal of Nuclear Medicine 2018 33(1):76-78

Crow-Fukase syndrome (POEMS syndrome) is a rare systemic paraneoplastic syndrome. Bone lesions are manifested by sclerotic osteoblastic lesions often associated with bone pain. Characterization of osseous lesions is always crucial for clinical correlation and better patient management. We present a case where 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET/CT) was unable to characterize a clinically symptomatic patient, and 18F-fluoride PET/CT showed excellent characterization of osteosclerotic lesions. The results were in correlation with already published data and showed that 18F-fluoride PET/CT has better uptake in osteoblastic lesions in POEMS syndrome when compared to18F-FDG PET/CT and have superior imaging quality in assessing the bone lesions.

http://ift.tt/2DhBNSn