The Many Faces of Intestinal Tract Gastric Heterotopia; A Series of Four Cases Highlighting Clinical and Pathological Heterogeneity

Publication date: Available online 7 January 2018
Source:Human Pathology
Author(s): Aqsa Nasir, Stuart K. Amateau, Sabina Khan, Ross W. Simpson, Dale C. Snover, Khalid Amin
Gastric heterotopia of the intestinal tract can have a diverse clinicopathologic presentation, resulting in a diagnostic dilemma. We present a series of four cases, two male and two female patients with age range of 31-82 year, found in the duodenum, jejunum, and transverse colon. The most common and rather unusual clinical presentation was iron deficiency anemia, seen in three cases, while one patient presented with abdominal pain. Endoscopically two cases were visualized as pedunculated polyps and two as sessile/plaques like lesions. Polypectomy was performed in three patients and one patient underwent biopsy followed by resection. Two cases showed oxyntic-type epithelium and two cases exhibited pylorictype gastric epithelium. Three patients were relieved of their presenting symptoms after therapeutic procedure with no evidence of recurrence noted on follow-up. Follow-up was not available on one patient. This case series highlights diverse clinicopathologic spectrum of gastric heterotopia. Accurate diagnosis is essential for proper management.



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