Scholar : Xenobiotica, Volume 48, Issue 6, June 2018 is now available online on Taylor & Francis Online

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The online platform for Taylor & Francis Online content Xenobiotica, Volume 48, Issue 6, June 2018 is now available online on Taylor & Francis Online. This new issue contains the following articles: General Xenobiochemistry Utility of in vitro and in vivo systems for studying the permeability of capsaicin and nonivamide through different intestinal regions Lian Duan, Huaidong Peng, Guangcan Li, Ruolun Wang & Yanfang Chen Pages: 541-545 | DOI: 10.1080/00498254.2017.1344790 In vitro metabolism of alectinib, a novel potent ALK inhibitor, in human: contribution of CYP3A enzymes Toshito Nakagawa, Stephen Fowler, Kenji Takanashi, Kuresh Youdim, Tsuyoshi Yamauchi, Kosuke Kawashima, Mika Sato-Nakai, Li Yu & Masaki Ishigai Pages: 546-554 | DOI: 10.1080/00498254.2017.1344910 In vitro evaluation of the inhibition and induction potential of olaparib, a potent poly(ADP-ribose) polymerase inhibitor, on cytochrome P450 Alex McCormick, Helen Swaisland, Venkatesh Pilla Reddy, Maria Learoyd & Graeme Scarfe Pages: 555-564 | DOI: 10.1080/00498254.2017.1346332 Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants Tsutomu Shimada, Norie Murayama, Kensaku Kakimoto, Shigeo Takenaka, Young-Ran Lim, Sora Yeom, Donghak Kim, Hiroshi Yamazaki, F. Peter Guengerich & Masayuki Komori Pages: 565-575 | DOI: 10.1080/00498254.2017.1347306 Altered hepatic drug-metabolizing activity in rats suffering from hypoxemia with experimentally induced acute lung impairment Yuki Hori, Yasumasa Shimizu & Tetsuya Aiba Pages: 576-583 | DOI: 10.1080/00498254.2017.1349969 Clinical Pharmacokinetics and Metabolism Absorption, metabolism and excretion of [14C]omarigliptin, a once-weekly DPP-4 inhibitor, in humans Shiyao Xu, Dan Tatosian, Ian Mcintosh, Maria Caceres, Catherine Matthews, Koppara Samuel, Diana Selverian, Sanjeev Kumar & Eunkyung Kauh Pages: 584-591 | DOI: 10.1080/00498254.2017.1346333 Disposition, profiling and identification of emixustat and its metabolites in humans Michael E. Fitzsimmons, Gang Sun, Vladimir Kuksa & Michael J. Reid Pages: 592-604 | DOI: 10.1080/00498254.2017.1350889 Animal Pharmacokinetics and Metabolism Profiling and identification of chlorogenic acid metabolites in rats by ultra-high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometer Fei Wang, Zhanpeng Shang, Lulu Xu, Zhibin Wang, Wenjing Zhao, XiaoDan Mei, Jianqiu Lu & Jia Yu Zhang Pages: 605-617 | DOI: 10.1080/00498254.2017.1343963 Identification of three new phase II metabolites of a designer drug methylone formed in rats by N-demethylation followed by conjugation with dicarboxylic acids Monika Židková, Igor Linhart, Marie Balíková, Michal Himl, Veronika Dvořáčková, Eva Lhotková & Tomáš Páleníček Pages: 618-625 | DOI: 10.1080/00498254.2017.1349964 Molecular Toxicology Mass spectrometry-based analysis of murine bronchoalveolar lavage fluid following respiratory exposure to 4,4'-methylene diphenyl diisocyanate aerosol Justin M. Hettick, Brandon F. Law, Chen-Chung Lin, Adam V. Wisnewski & Paul D. Siegel Pages: 626-636 | DOI: 10.1080/00498254.2017.1344791 Xenobiotic Transporters In vitro drug–drug interactions of budesonide: inhibition and induction of transporters and cytochrome P450 enzymes | Nancy Chen, Donghui Cui, Qing Wang, Zhiming Wen, Richard D. Finkelman & Devin Welty Pages: 637-646 | DOI: 10.1080/00498254.2017.1344911 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.