Publication date: Available online 29 March 2018
Source:Trends in Endocrinology & Metabolism
Author(s): Peter Mirtschink, Triantafyllos Chavakis
Notch signaling contributes to maintenance of adult tissue homeostasis and is also involved in disease. A recent study demonstrates that inhibition of Dll4–Notch signaling by anti-Dll4 improves pancreatic islet function and insulin production by multiple complementary mechanisms. Thus, anti-Dll4 represents a therapeutic approach for compromised insulin production in diabetes.
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Παρασκευή 30 Μαρτίου 2018
The Missed Notch to Bring Down Diabetes
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Abstract The changes of dissolved organic matter (DOM) components during stabilization process play significant effects on its redox prope...
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Publication date: September 2017 Source: European Journal of Surgical Oncology (EJSO), Volume 43, Issue 9 http://ift.tt/2gezJ2D
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