Two Cases of Fungal Keratitis Caused by Metarhizium anisopliae

Publication date: Available online 6 March 2018
Source:Medical Mycology Case Reports
Author(s): Abigail L. Goodman, Shawn R. Lockhart, Colleen B. Lysen, Lars F. Westblade, Carey-Ann D. Burnham, Eileen M. Burd
We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates had low minimum inhibitory concentration (MIC) values to caspofungin and micafungin, but high MIC values to amphotericin B. The morphologic and antifungal susceptibility differences between the two isolates indicate possible polyphylogeny of the group.



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