Mitosis-Resistant Adhesions Provide Molecular Memory to Dividing Cells

Publication date: 9 April 2018
Source:Developmental Cell, Volume 45, Issue 1
Author(s): Guillaume Jacquemet, Johanna Ivaska
During mitosis, animal cells disassemble focal adhesions and round up while remaining attached to the substrata via actin cables and unknown adhesive structures. In this issue of Developmental Cell, Dix et al. (2018) describe integrin-positive adhesions, devoid of classical focal adhesion components, that persist throughout mitosis to contribute to re-spreading.

Teaser

During mitosis, animal cells disassemble focal adhesions and round up while remaining attached to the substrata via actin cables and unknown adhesive structures. In this issue of Developmental Cell, Dix et al. (2018) describe integrin-positive adhesions, devoid of classical focal adhesion components, that persist throughout mitosis to contribute to re-spreading.


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