Asparagine and Glutamine: Co-conspirators Fueling Metastasis

Publication date: 1 May 2018
Source:Cell Metabolism, Volume 27, Issue 5
Author(s): Ming Luo, Michael Brooks, Max S. Wicha
Cancer cells frequently hijack normal metabolic pathways to promote their growth and metastasis. Two recent papers by Knott et al. (2018) and Pavlova et al. (2018) demonstrate that asparagine and glutamine work in concert to drive tumor growth and metastasis through modulation of cell survival, growth, and EMT regulatory pathways.

Teaser

Cancer cells frequently hijack normal metabolic pathways to promote their growth and metastasis. Two recent papers by Knott et al. and Pavlova et al. demonstrate that asparagine and glutamine work in concert to drive tumor growth and metastasis through modulation of cell survival, growth, and EMT regulatory pathways.


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