General Xenobiochemistry Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor
Jamie E. Moscovitz, Zhiwu Lin, Nathaniel Johnson, Meihua Tu, Theunis C. Goosen, Yan Weng & Amit S. Kalgutkar
Pages: 647-655 | DOI: 10.1080/00498254.2017.1353163
Marmoset pulmonary cytochrome P450 2F1 oxidizes biphenyl and 7-ethoxycoumarin and hepatic human P450 substrates
Shotaro Uehara, Yasuhiro Uno, Toru Oshio, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki
Pages: 656-662 | DOI: 10.1080/00498254.2017.1354138
Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims
Raghava Choudary Palacharla, Ramakrishna Nirogi, Venkatesham Uthukam, Arunkumar Manoharan, Ranjith Kumar Ponnamaneni & Ilayaraja Kalaikadhiban
Pages: 663-675 | DOI: 10.1080/00498254.2017.1354267
Effects of m-nisoldipine on the activity and mRNA expression of four CYP isozymes in rats
Yupeng Sun, Yanyan Liu, Xia Zhang, Changchen Wan, Tao Lyu & Lantong Zhang
Pages: 676-683 | DOI: 10.1080/00498254.2017.1358831
Toluene and methylethylketone: effect of combined exposure on their metabolism in rat
Frédéric Cosnier, Hervé Nunge, Élodie Bonfanti, Stéphane Grossmann, Anne-Marie Lambert-Xollin, Samuel Muller, Sylvie Sébillaud, Aurélie Thomas, Laurent Gaté & Pierre Campo
Pages: 684-694 | DOI: 10.1080/00498254.2017.1362604
Expression of cytochrome P450 regulators in cynomolgus macaque
Yasuhiro Uno & Hiroshi Yamazaki
Pages: 695-703 | DOI: 10.1080/00498254.2017.1363928
Clinical Pharmacokinetics and Metabolism The metabolism and drug–drug interaction potential of the selective prostacyclin receptor agonist selexipag
Carmela Gnerre, Jérôme Segrestaa, Swen Seeland, Päivi Äänismaa, Thomas Pfeifer, Stephane Delahaye, Ruben de Kanter, Tomohiko Ichikawa, Tetsuhiro Yamada & Alexander Treiber
Pages: 704-719 | DOI: 10.1080/00498254.2017.1357088
Animal Pharmacokinetics and Metabolism Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19
Akiko Toda, Shotaro Uehara, Takashi Inoue, Masahiro Utoh, Takashi Kusama, Makiko Shimizu, Yasuhiro Uno, Masayuki Mogi, Erika Sasaki & Hiroshi Yamazaki
Pages: 720-726 | DOI: 10.1080/00498254.2017.1353716
Uptake and metabolism of carbamazepine (CBZ) by clam Ruditapes decussatus and its effects in biochemical responses
Khazri Abdelhafidh, Mezni Ali, Khazri Hassen, Sellami Badreddine, Aceña Jaume, Pérez Sandra, Eljarrat Ethel, Barceló Damià, Beyrem Hamouda & Mahmoudi Ezzeddine
Pages: 727-733 | DOI: 10.1080/00498254.2017.1354268
Xenobiotic Transporters Effect of inhalation exposure to toluene on the activity of organic anion transporting polypeptide (Oatp) using pravastatin as a probe drug in rats
Mariana Mauro, Jose Salvador Lepera, Bruno Borsari, Jorge Manuel Vieira Capela & Natália Valadares de Moraes
Pages: 734-738 | DOI: 10.1080/00498254.2017.1353717
Intestinal absorption of pallidifloside D are limited by P-glycoprotein in mice
Ming-Yu Wang, Ming Yang, Pi-Yong Hou, Xiu-Bo Chen, Hong-Gang Li, Jiu-Xing Yan, Jun Zhang, Yan-Wen Zhang & Xiao-Hui Wu
Pages: 739-744 | DOI: 10.1080/00498254.2017.1355999
Honey flavonoids inhibit hOATP2B1 and hOATP1A2 transporters and hOATP-mediated rosuvastatin cell uptake in vitro
Lucie Navrátilová, Jana Ramos Mandíková, Petr Pávek, Přemysl Mladěnka & František Trejtnar
Pages: 745-755 | DOI: 10.1080/00498254.2017.1358469
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