Ετικέτες

Παρασκευή 15 Ιουνίου 2018

Epigenetic Editing: Repurposing for Rescue

Publication date: Available online 14 June 2018
Source:Trends in Biochemical Sciences
Author(s): Hari R. Singh
The epigenome editing framework provides an engineering approach to explore chromatin-based gene expression mechanisms. However, therapeutic utility of epigenetic editing-based systems has been lacking. A report in Cell (Liu et. al., 2018) shows that epigenetic editors can revert abnormal heterochromatin formation at the gene promoter leading to restoration of FMR1 gene expression, functionally rescuing fragile X syndrome (FXS), an otherwise unamenable genetic disorder.



https://ift.tt/2tapMpL

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Αναζήτηση αυτού του ιστολογίου