Siderophore-based biosensors and nanosensors; new approach on the development of diagnostic systems

Publication date: 15 October 2018
Source:Biosensors and Bioelectronics, Volume 117
Author(s): Rahim Nosrati, Sadegh Dehghani, Bahareh Karimi, Meysam Yousefi, Seyed Mohammad Taghdisi, Khalil Abnous, Mona Alibolandi, Mohammad Ramezani
Siderophores are small organic compounds secreted by microorganisms under iron-depleted conditions which enhance the uptake of iron. Siderophores can play vital roles in ecology, agriculture, bioremediation, biosensor, and medicine. In recent years, the concept of siderophore-based biosensing devices has opened new horizons in high precision detection of various metal ions especially the iron, microorganisms, phosphopeptides, antibiotics as well pesticides. Once combined with nanomaterials, nano-scale siderophore systems provide powerful analytical platforms for detection of low concentration of metal ions and numerous pathogens. In this article, a brief overview of general aspects of siderophore is firstly discussed. In addition, a clear and concise review of recent advances of siderophore-based biosensors (siderosensor) and nanosensors are mainly discussed herein. Subsequently, future perspectives and challenges of siderophore-based sensors are discussed briefly.



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