Synergistic Mechano-Chemical Sensing by Vascular Cilia

Publication date: Available online 2 May 2018
Source:Trends in Cell Biology
Author(s): Gautier Follain, Jacky G. Goetz
Endothelial cells can sense and respond to blood flow forces and signals, but the exact mechanisms employed remain poorly understood. A recent study describes how low-flow forces are sensed by primary cilia during development of the retinal vasculature, which sensitizes endothelial cells to BMP signaling.



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