Assessment of the Impact of Perioral Rejuvenation With Hyaluronic Acid Filler on Projected First Impressions and Mood Perceptions

BACKGROUND Small-particle hyaluronic acid filler is approved for lip augmentation and correction of perioral rhytides. Treatment with this product may improve facial aesthetics, projected first impression, and self-perception of mood. OBJECTIVE To determine the effect of perioral rejuvenation with hyaluronic acid on patient perception of mood and projected first impression. MATERIALS AND METHODS Seventeen subjects underwent perioral rejuvenation treatment with small-particle hyaluronic acid filler. Each subject underwent photography and completed 2 surveys measuring self-perception of mood before treatment and after achieving an optimal cosmetic result. Aesthetic improvement with treatment was assessed using the Global Aesthetic Improvement Scale and the Oral Commissure Severity and Perioral Line Severity scales. Seventeen hundred blinded evaluators rated pre-treatment and post-treatment photographs of the subjects using a First Impressions Questionnaire. RESULTS Perioral filler treatment significantly improved pre-treatment and post-treatment scores for happiness within the Happiness Measures Scale. This treatment was found to significantly improve projected first impression across all categories. CONCLUSION Small-particle hyaluronic acid filler treatment for perioral rejuvenation is an effective method for improving physical appearance as well as first impressions. Larger studies are necessary to verify whether perioral rejuvenation with hyaluronic acid offers enhanced self-perception of mood. Address correspondence and reprint requests to: Steven H. Dayan, MD, FACS, DeNova Research, 845 N. Michigan Avenue, Suite 923E, Chicago, IL 60611, or e-mail: sdayan@drdayan.com Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (https://ift.tt/2bw6lgr). Supported by a grant from Galderma Laboratories, L.P. to S.H. Dayan. S.H. Dayan received equipment, materials, and medications for this study, and received funding to support research for this article. The authors have indicated no significant interest with commercial supporters. This study was an investigator-initiated trial in which Galderma laboratories, L.P. did not create the design or conduct the study; Galderma laboratories, L.P. was not involved in the collection management, analysis, and interpretation of the data; Galderma laboratories L.P. did participate in the preparation of this manuscript following the draft by reviewing content for scientific accuracy of their products and approval of the manuscript; Galderma laboratories, L.P. was involved in the decision to submit this manuscript for publication. S.H. Dayan had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. A. Kalbag is affiliated with DeNova Research and is responsible for the data analysis. © 2018 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.

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