Optimal Multimodal Treatment for Desmoplastic Small Round Cell Tumors

To the Editor We read with great attention the article by Tun et al describing a case of advanced desmoplastic small round cell tumor (DSRCT) and discussing its optimal management. Although we agree with the authors on the fact that data are scarce on the clinical management of advanced DSRCT, we would like to comment on several issues regarding the current knowledge on the optimal, multimodal management of advanced DSRCT. First, we would like to point out that the benefit of hyperthermic intraperitoneal chemotherapy seems to be limited in patients with extraperitoneal disease. Second, whole abdominal radiotherapy was associated with better outcomes (and in particular peritoneal disease control rate) in large and recent series, in contrast with the authors' statement.

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