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Παρασκευή 28 Σεπτεμβρίου 2018

Scholar : Xenobiotica, Volume 48, Issue 11, November 2018 is now available online on Taylor & Francis Online

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Xenobiotica, Volume 48, Issue 11, November 2018 is now available online on Taylor & Francis Online.



This new issue contains the following articles:

General Xenobiochemistry

Metabonomics analysis of serum from rats given long-term and low-level cadmium by ultra-performance liquid chromatography–mass spectrometry
Liyan Hu, Lu Bo, Meiyan Zhang, Siqi Li, Xiujuan Zhao & Changhao Sun
Pages: 1079-1088 | DOI: 10.1080/00498254.2017.1397811


The impact of sesquiterpenes β-caryophyllene oxide and trans-nerolidol on xenobiotic-metabolizing enzymes in mice in vivo
Kateřina Lněničková, Hana Svobodová, Lenka Skálová, Martin Ambrož, Filip Novák & Petra Matoušková
Pages: 1089-1097 | DOI: 10.1080/00498254.2017.1398359


Indirect activation of pregnane X receptor in the induction of hepatic CYP3A11 by high-dose rifampicin in mice
Yuki Yamasaki, Kaoru Kobayashi, Asumi Inaba, Daisuke Uehara, Hiroki Tojima, Satoru Kakizaki & Kan Chiba
Pages: 1098-1105 | DOI: 10.1080/00498254.2017.1400128


Animal Pharmacokinetics and Metabolism

Changes in gefitinib, erlotinib and osimertinib pharmacokinetics under various gastric pH levels following oral administration of omeprazole and vonoprazan in rats
Osamu Yasumuro, Shinya Uchida, Yasuharu Kashiwagura, Ayae Suzuki, Shimako Tanaka, Naoki Inui, Hiroshi Watanabe & Noriyuki Namiki
Pages: 1106-1112 | DOI: 10.1080/00498254.2017.1396379


Metabolism of metofluthrin in rats: II. Excretion, distribution and amount of metabolites
Jun Abe, Yoshitaka Tomigahara, Hirokazu Tarui, Hirohisa Nagahori, Motohiro Kurosawa, Kenji Sugimoto & Naohiko Isobe
Pages: 1113-1127 | DOI: 10.1080/00498254.2017.1397813


Disposition of [14C]hydroquinone in Harlan Sprague-Dawley rats and B6C3F1/N mice: species and route comparison
Sherry R. Black, Timothy R. Fennell, James M. Mathews, Rodney W. Snyder, Purvi R. Patel, Scott L. Watson, Vicki Sutherland & Suramya Waidyanatha
Pages: 1128-1141 | DOI: 10.1080/00498254.2017.1398847


Metabolism and disposition of 2-ethylhexyl-p-methoxycinnamate following oral gavage and dermal exposure in Harlan Sprague Dawley rats and B6C3F1/N mice and in hepatocytes in vitro
Timothy R. Fennell, James M. Mathews, Rodney W. Snyder, Yan Hong, Scott L. Watson, Sherry R. Black, Barry S. McIntyre & Suramya Waidyanatha
Pages: 1142-1156 | DOI: 10.1080/00498254.2017.1400129


Effects of glycyrrhizin on the pharmacokinetics of puerarin in rats
Qun Zhao, Yingli Wang, Hongqin Wang & Lichun Feng
Pages: 1157-1163 | DOI: 10.1080/00498254.2017.1401155


Molecular Toxicology

Identification and analysis of the reactive metabolites related to the hepatotoxicity of safrole
Ai-Hong Yang, Lei Zhang, De-Xian Zhi, Wen-Li Liu, Xue Gao & Xin He
Pages: 1164-1172 | DOI: 10.1080/00498254.2017.1399227


Xenobiotic transporters

Efflux transporter breast cancer resistance protein dominantly expresses on the membrane of red blood cells, hinders partitioning of its substrates into the cells, and alters drug–drug interaction profiles
Pu Shi, Mingxiang Liao, Bei-Ching Chuang, Robert Griffin, Judy Shi, Marc Hyer, John K. Fallon, Philip C. Smith, Chao Li & Cindy Q. Xia
Pages: 1173-1183 | DOI: 10.1080/00498254.2017.1397812


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