Publication date: Available online 11 February 2019
Source: Journal of the American Academy of Dermatology
Author(s): Khaled Ezzedine, Maggi Ahmed, Andrea Tovar-Garza, Carla Hajj, Maxine Whitton, Amit Pandya, Saad Altalhab, Julien Seneschal, John Harris, Charles Taieb
Abstract
Background
there is a lack for short forms questionnaire evaluating the burden of Vitiligo according to skin phototype
Objective
To develop and validate a 12-item short-form of the Vitiligo Impact Patient Scale (VIPs) that takes into account skin phototype.
Methods
Multicentric, prospective, cross-sectionnal study conducted in France (Créteil and Bordeaux) and the US (Worcester, Massachusetts and Dallas, Texas).
Results
In total, 891 patients completed the questionnaire. Of these, 509 patients belonged to the French development sample, i.e. 313 with dark skin (DS) (phototype IV to VI) and 196 with fair skin (FS) (phototype I to III). The American validation sample comprised 382 patients, i.e. 113 DS and 269 FS. There was a very high correlation between VIPs-FS and its 12-item short form, VIPs-12-FS, in both the development and validation samples (respectively rho=0.96, pvalue <0.0001 and rho=0.98, pvalue <0.0001). Similarly, the correlations between VIPs-DS and the short form, VIPs-12-DS, in both the development and validation samples were very high (respectively rho=0.95, pvalue <0.0001 and rho=0.96, pvalue <0.0001).
Limitations
Responsiveness of the 12-item short forms should be confirmed
Conclusions
These data enabled the development and validation of 12-item short forms of the VIPs questionnaires for fair (VIPs-12-FS) and dark (VIPs-12-DS) skin.
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