Publication date: Available online 25 March 2019Source: Journal of Neuroscience MethodsAuthor(s): Osama Habbal, Ahmad Farhat, Reem KhalilAbstractBackgroundTraditional methods for mounting tissue sections onto slides are suboptimal as the amount of labor required quickly multiplies with increasing number of samples. Methods to accelerate the tissue mounting process while reducing the associated risk of tissue damage are needed.New MethodWe designed and 3D printed a mechanized device with an inclined...
Tue Mar 26, 2019 16:48
Abstract Background Postnatal closure of a myelomeningocele remains the standard of care in many countries. The prenatal closure has given hope for decreasing the damage to the neural placode and has challenged classic management. However, this technique presents potential sources of complications. Patients with MMC with an anatomical level of L4 and below have a better functional prognosis than higher level malformations. Are they still...
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Abstract Purpose To identify if specific findings on magnetic resonance imaging (MRI) cerebrospinal fluid (CSF) flow studies can be utilised to identify which patients with idiopathic normal pressure hydrocephalus (iNPH) will have improved gait following a CSF tap test (TT). Methods Prospective study of patients undergoing a CSF TT for iNPH. Functional gait...
Tue Mar 26, 2019 02:00
Grasping movement in primates is known to be a visually guided behavior and the aperture of hand opening is adjusted to the target size on the basis of visual information. The analogous behavior can be found in birds, called 'pecking', consisting of head-reaching and bill-grasping. Bill-grasping has been investigated mainly in pigeons and an aperture adjustment as seen in primates has been reported. This study focused on kinematics of pecking in crows, known to possess dexterous visuomotor skills,...
Thu Mar 07, 2019 02:00
An electromagnetic pulse (EMP) can cause central nervous system damage, but the underlying mechanisms remain unclear. In this study, we investigated the effects of EMP exposure on the cortex of the rat brain and the involvement of deficiencies in the brain-derived neurotrophic factor (BDNF)–tyrosine receptor kinase B (TrkB) signaling pathway. Rats were exposed to EMPs once a day for 7 consecutive days. Histopathological damage was assessed by hematoxylin and eosin staining. Levels of synaptic marker...
Thu Mar 07, 2019 02:00
Follow-up observation is needed for type 1 diabetes mellitus (T1DM) children due to the potential injury to the brain. However, the effect of short-term T1DM on gray matter in school-aged children is still unclear. This study aimed to evaluate gray matter volume (GMV) changes and their relationships with clinical variables in school-aged children with short-term T1DM. Twenty-one school-aged T1DM children were compared with 21 control patients, matched for sex and age. T1-weighted gradient echo three-dimensional...
Thu Mar 07, 2019 02:00
Publication date: Available online 25 March 2019Source: Brain Research BulletinAuthor(s): Ivar von KügelgenAbstractP2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups (P2Y1, P2Y2, P2Y4, P2Y6, and P2Y11) and (P2Y12, P2Y13, and P2Y14). The P2Y receptors are expressed in various cell types and play important roles in physiology and pathophysiology including inflammatory responses and neuropathic...
Tue Mar 26, 2019 15:48
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Cheng Li, Na Sun, Lei Li, Jingzhu Duan, Yingkai ZhangAbstractObjectiveThis study aimed to explore the feasibility and effectiveness of C1 lateral mass fixation via the posterior arch using pedicle screws of 3.5-mm diameter in patients whose atlas in the vertebral artery groove (C1 pedicle) was ≤3.5 mm in height.MethodsA total of 14 patients who underwent transposterior arch lateral mass screw fixation between 2014...
Tue Mar 26, 2019 16:47
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Matheus Fernandes de Oliveira
Tue Mar 26, 2019 16:47
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Jin Yang, Hao Wu, Qingquan Kong, Yu Wang, Zhiyu Peng, Lifeng Zhang, Yuqing Yan, Chuan Guo, Dongfeng Zhang
Tue Mar 26, 2019 16:47
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Kristine Ravina, Daniel R. Kramer, Ben A. Strickland, Erik M. Wolfswinkel, Robert C. Rennert, Joseph N. Carey, Jonathan J. RussinAbstractRevascularization is an important strategy when treating cerebrovascular occlusive disease and complex aneurysms. Radial artery fascial flow-through free flaps (RAFFs) are flexible grafts that provide direct and indirect revascularization. RAFFs can be especially useful for large...
Tue Mar 26, 2019 16:47
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Shunsuke Nomura, Hiroyuki Akagawa, Koji Yamaguchi, Tatsuya Ishikawa, Akitsugu Kawashima, Hidetoshi Kasuya, Maki Mukawa, Tadashi Nariai, Taketoshi Maehara, Yoshikazu Okada, Takakazu KawamataAbstractBackgroundMoyamoya syndrome (MMS), distinguished from definite moyamoya disease (MMD), is characterized by moyamoya vasculopathy thought to develop secondary to underlying conditions (e.g., hyperthyroidism). Recent studies...
Tue Mar 26, 2019 16:47
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Yangpu Zhang, Yong Hai, Luming Tao, Jincai Yang, Lijin Zhou, Peng Yin, Aixing Pan, Yaoshen Zhang, Chang LiuAbstractObjectiveTo evaluate the efficacy and safety of posterior multiple level asymmetrical Ponte osteotomies (MAPO) for rigid adult idiopathic scoliosis (AdIS).MethodsA retrospective study was conducted for adult patients with rigid idiopathic scoliosis (flexibility of main curve <25%), who underwent one-stage...
Tue Mar 26, 2019 16:47
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Benjamin Hopkins, Kenneth A. Weber, Kartik Kesavabhotla, Monica Paliwal, Donald Cantrell, Zachary A. Smith
Tue Mar 26, 2019 16:47
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Sandeep Kandregula, Manish Beniwal, Dwarakanath Srinivas, Radhika Mhatre
Tue Mar 26, 2019 16:47
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Jack Horan, Sean Tromp, Ncedile MankahlaAbstractBackgroundLocked-in syndrome (LIS) is a rare neurological disorder characterised as quadriplegia with anarthria. The diagnosis of LIS is challenging and requires a high index of suspicion. The syndrome is typically due to an infratentorial lesion to the ventral pons, regardless of aetiology. LIS secondary to supratentorial injury is extremely rare and to our knowledge...
Tue Mar 26, 2019 16:47
Publication date: Available online 25 March 2019Source: World NeurosurgeryAuthor(s): Toshinori Hasegawa, Takenori Kato, Takehiro Naito, Takafumi Tanei, Jun Torii, Kazuki Ishii, Eisuke TsukamotoAbstractObjectiveLittle is known about long-term outcomes for pediatric brain arteriovenous malformations (AVMs) treated with gamma knife radiosurgery (GKRS). This study investigates annual hemorrhage rates and nidus obliteration rates, and the factors affecting them, in pediatric AVMs treated with GKRS.MethodsWe...
Tue Mar 26, 2019 16:47
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