1
Somatosensory Tinnitus Study Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Functional Index Tinnitus Loudness-Match VA Portland Health Care System, Portland, OR
Auditory-somatosensory Stimulation to AlleviateTinnitus Device: Sham Treatment: unimodal auditory stimulation Device: Active Treatment: Bimodal auditory-somatosensory stimulation Allocation: Randomized Intervention Model: Crossover Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Change in TFI (Tinnitus Functional Index) After Treatment or Sham Compared to Baseline Change in Tinnitus Loudness as Assessed by TinnTester University of Michigan Kresge Hearing Research Institute
Tinnitus Related Cerebral ActivitiesOther: Functional brain MRI Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Basic Science Measure of the BOLD activity by MRI Measure of the BOLD activity on resting state by MRI
Tinnitus rTMS 2013Device: E-fied navigated rTMS Device: non-navigated rTMS Device: sham E-field navigated rTMS Device: Navigated rTMS Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment The change of loudness and pitch of the tinnitus is psychophysically measured, VAS questionnaires, Tinnitus Handicap Inventory, Tinnitus diary Turku University Hospital
A Clinical Trial Investigating Effect of Tinted Light on Perception of Tinnitus Other: Visual Stimulus Condition Set Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Basic Science Averaged difference between dark and optimal tint tinnitus annoyance Visual Analogue Score (VAS) Averaged difference between dark and optimal tint tinnitus loudness Visual Analogue Score (VAS) Leicester Royal Infirmary University Hospitals Trust
Lidoderm Patch (Lidocaine 5%) for Tinnitus Treatment Device: Lidoderm patch (Lidocaine 5% patch) Other: Tegaderm patch. (neutral patch, containing no drug) Procedure: blood test- serum lidocain levels Other: Hearing tests Allocation: Randomized Intervention Model: Crossover Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment questionnaire results change- tinnitus handicap inventory questionnaire results- Pittsburgh sleep quality index tinnitus loudness- visual analogue scale (VAS) tinnitus suffer - visual analogue scale (VAS) Haemek Medical Center
Effects of Yoga Exercise on Participates With Tinnitus Observational Model: Case-Only Time Perspective: Prospective Change from Assessment of the degree of tinnitus Assessment of the degree of sleep quality. Dalin Tzu Chi General Hospital
OTO-313 in Subjects With Subjective Tinnitus Drug: OTO-313 Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment Treatment Emergent Adverse Events Audiometry Otoscopic Examinations Plasma Pharmacokinetics (PK) Worldwide Clinical Trials
A CBT-based Internet Intervention for Adults WithTinnitus in the United Kingdom Behavioral: CBT-based internet-intervention for tinnitus Allocation: Randomized Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment The Tinnitus Functional Index Tinnitus Handicap Inventory-screening version Insomnia Severity Index (and 6 more...) Vision and hearing Sciences, Anglia Ruskin Univeristy
Repetitive Transcranial Magnetic Stimulation as a Treatment for Tinnitus Device: Active rTMS 1 Device: Active rTMS 2 Device: Active rTMS 3 Device: sham condition Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Outcomes Assessor) Primary Purpose: Treatment Change of tinnitus severity as measured by the Tinnitus Handicap Inventory (THI) Beck's Depression Inventory (BDI) State-Trait Anxiety Inventory (STAI) (and 2 more...) Seoul National University Hospital
Treating Tinnitus Using the Neuromonics Tinnitus Treatment Program: A Randomized, Double-blind Study Device: Neuromonics Tinnitus Treatment Program Device: Placebo Device Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary Purpose: Treatment Tinnitus Reaction Questionnaire (TRQ) Tinnitus Reaction Questionnaire (TRQ) Midterm Tinnitus Reaction Questionnaire (TRQ) Awareness (and 5 more...) U.S. Army Aeromedical Research Laboratory
The Effect of Cervical Physical Therapy Treatment in Patients With Somatic Tinnitus Other: Cervical physical therapy Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Outcomes Assessor) Primary Purpose: Treatment Tinnitus Questionnaire Tinnitus Functional Index Neck Bournemouth Questionnaire (and 7 more...) University Hospital of Antwerp
A Randomized Controlled HD-tDCS Trial: Effects on Tinnitus Severity and Cognition Device: tDCS Device: sham tDCS Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment Tinnitus Functional Index Tinnitus Questionnaire (TQ) Speech, Spatial and Qualities of Hearing Scale-12 (SSQ-12) (and 7 more...) Antwerp University Hospital
EMA-Defined Tinnitus Subgroups Observational Model: Case-Only Time Perspective: Prospective Ecological Momentary Assessment of Tinnitus Tinnitus Functional Index (TFI) Washington University
A Feasibility Study Assessing the Effectiveness of rTMS inTinnitus Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Improvement in tinnitus severity following treatment with rTMS The number of patients willing to complete the trial Confirm acceptability of trial design to participants (and 3 more...) Sheffield Teaching Hospitals NHS Foundation Trust
New Therapy for Patients With Severe Tinnitus Other: Sound Based and Educational Therapies Other: Integrative Medicine Therapies and Sound Based Education Therapies Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Investigator, Outcomes Assessor) Primary Purpose: Other Feasibility of implementing the integrative medicine intervention in an RCT patient satisfaction Duke University Medical Center
Cognitive Training for Firefighters With Tinnitus Behavioral: Brain Fitness Program - Tinnitus Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Change from Baseline in Tinnitus Handicap Inventory at 8 weeks post Brain Fitness use. Change in Baseline Tinnitus Bother Score at 8 weeks post Brain Fitness Program Use. Washington University School of Medicine
Impact of Neurostimulation on Patterns of Brain Electrical Activity in Patients WithTinnitus Device: Transcranial Direct Current Stimulation Device: Sham Transcranial Direct Current Stimulation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Tinnitus Handicap Inventory Visual Analogue Scales (VAS) of perceived tinnitus loudness and distress Acuphenometry Dayse Souza
Internet-based Versus Face-to-face Clinical Care forTinnitus Behavioral: CBT-based internet-intervention for tinnitus Behavioral: Face-to-face clinical tinnitus care Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment The Tinnitus Functional Index questionnaire: change from baseline Tinnitus Handicap Inventory-screening version questionnaire:change from baseline Insomnia Severity Index Questionnaire, change from baseline (and 6 more...) Norfolk and Norwich University Hospital Hinchingbrooke Hospital Milton Keynes University Hospital
Treating Tinnitus Using Eutectic Mixture of Local Anesthetics (EMLA) 5% Cream Drug: EMLA cream 5% Other: cetomacrogol cream (lotion cream) Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment questionnaire results- Beck depression questionnaire questionnaire results- Pittsburgh sleep quality index questionnaire results- tinnitus handicap inventory questionnaire results - Beck depression questionnaire
Implantation of an Auditory Brainstem Implant for the Treatment of Incapacitating Unilateral Tinnitus Device: Auditory brainstem implant Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Functioning Index (TFI) Pure tone audiometry Tinnitus Handicap Inventory (THI) (and 3 more...) University Medical Center Groningen
Evaluation of Adding Lidocaine to Dexamethasone in Intra-tympanic Injection for Management of Tinnitus Drug: Intra-tympanic injection of drugs Other: Data management of intratympanic drugs Allocation: Randomized Intervention Model: Crossover Assignment Masking: Double (Participant, Care Provider) Primary Purpose: Treatment measuring tinnitus scales improvements by using dexmethsone alone and by using combined lidocaine and tinnitus measuring medication complication and side effect by using hearing test indicators
A Comparison of Three Psychoeducational Group Interventions for Veterans WithTinnitus Behavioral: Coping Effectiveness Training Behavioral: Cognitive-behavioral therapy Behavioral: Acceptance and Commitment Therapy Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment VA Portland Health Care System, Portland, OR
Exploration of Cortical Neural Network in Patients With Bothersome Tinnitus Behavioral: Task-Based Functional Magnetic Resonance Imaging (fMRI) Observational Model: Case Control Time Perspective: Prospective Washington University School of Medicine
Internet-based Self-help forTinnitus : The Role of Support Behavioral: iCBT (internet-based, cognitive-behavioural therapy) Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Change in tinnitus distress Change in depressive Symptoms Change in tinnitus-related thoughts Change of tinnitus acceptance Philipps University Marburg, Dept. of Psychology, Division of Clinical Psychology and Psychotherapy
Experimental Tinnitus Treatment With Transcranial Magnetic Stimulation Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment University of Iowa
Deanxit and Rivotril inTinnitus Patients Drug: Deanxit Drug: Lactose placebo Allocation: Randomized Intervention Model: Crossover Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Antwerp University Hospital
Effects of Kinesio Taping in Patients With SomatosensoryTinnitus Other: Kinesio tape Other: Shame tape Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Tinnitus handicap Index (THI) Tinnitus severity (tinnitus-VAS) Cervical pain (cervical-VAS) Neck Disability index score (NDI)
Effectiveness of Cannabis in the Treatment of Tinnitus Patients Drug: Cannabis Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Tinnitus handicap inventory score Wolfson Medical Centre
Phase Out in Tinnitus Patients Device: Phase Out treatment in pure tone tinnitus patients Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Visual Analogue Scale Score on Tinnitus Questionnaire Antwerp university Hospital
Nitrous Oxide Treatment forTinnitus Drug: Nitrous oxide gas for inhalation Drug: Placebo gas for inhalation Allocation: Randomized Intervention Model: Crossover Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Change in Tinnitus Functional Index (TFI) Score Change in Global Bothersome Scale (GBS) Score Patients' Global Impression of Change Washington University School of Medicine
Efficacy of AM 101 in Patients With Acute Inner Ear Tinnitus Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Change in the minimum masking level from Baseline to Day 90 Standard audiological evaluations Questionaires evaluating the impact of tinnitus Bundeswehrkrankenhaus Ulm
Study on the Effect of Sound Therapy on Chronic PrimaryTinnitus Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment Tinnitus Handicap Inventory ( THI) Resting-state function magnetic resonance imaging(RS-fMRI) Regional homogeneity(ReHo) value Resting-state function magnetic resonance imaging(RS-fMRI) low-frequency wave amplitude (ALFF) Visual Analogue Scale(VAS) Beijing Friendship Hospital,Capital Medical University
Zinc to Treat Tinnitus in the Elderly Drug: Zinc Drug: Placebo oral capsule Allocation: Randomized Intervention Model: Crossover Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Change From Baseline in Tinnitus Reaction on the Tinnitus Handicap Questionnaire Scores (0-100) at 4 Months Changes on Baseline Tinnitus Magnitude on Tinnitus Loudness Rating Scores (0-100) at 4 Months Treatment Changes on Baseline Tinnitus Reactions on Tinnitus Annoyance Rating Scores (0-100) at 4 Months Treatment University of Iowa
Cochlear Promontory Stimulation for Treatment ofTinnitus Device: Cochlear promontory stimulation Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Short Term Relief of Tinnitus as Measured by the Tinnitus Handicap Inventory Optimal Location of Tinnitus Relief Auditory Feedback (and 3 more...) Mayo Clinic in Rochester
Vardenafil in Tinnitus Drug: Levitra (Vardenafil, BAY38-9456) Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Total score of the Tinnitus Audiometric measurements (mode, frequency and loudness of tinnitus, pure tone audiogram, speech audiogram) Quality of life (SF 36 Questionnaire) (and 2 more...) Berlin, Berlin / 285, Germany
Treatment Evaluation of Neuromodulation for Tinnitus - Stage A2 Device: PS1-PS4 Device: PS6-PS10 Device: PS7-PS4 Device: PS9-PS6 Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary Purpose: Treatment Tinnitus Handicap Inventory (THI) St. James's Wellness Trust Clinical Research Facility
Acoustic and Electrical Stimulation for the Treatment of Tinnitus Other: Electrical Other: Acoustic Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Audiogram Otoacoustic Emissions Tinnitus Handicap Inventory Medical Outcomes Study Questionnaire Short Form 36 Health Survey Quality of life metrics. Hamid R. Djalilian
Tinnitus Suppression for Cochlear Implant RecipientsIntervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Severity Questionnaire Word recognition scores in quiet Speech recognition scores in noise Degree of handicap as a result of tinnitus The HEARing CRC
Transcranial Direct Current Stimulation (tDCS) for the Treatment of Tinnitus Device: BrainSTIM Transcranial Stimulator Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Tinnitus Handicap Inventory (THI; Newman, Jacobson, & Spitzer, 1996; French version: Ghulyan-Bédikian et al., 2010) Tinnitus Handicap Inventory (THI) Visual Analogue Scales (VAS) of perceived tinnitus loudness and distress (and 3 more...) Department of Neurology, Centre Hospitalier Universitaire Vaudois
EMDR as a Treatment forTinnitus Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Change in tinnitus handicap inventory score Beck Depression Inventory (T0, T1, T2) Beck Anxiety Inventory(T0, T1, T2) (and 5 more...) Norfolk and Norwich University Hospital
Vagus Nerve Stimulation (VNS) Paired With Tones forTinnitus Device: VNS Treatment Device: VNS Control Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Outcomes Assessor) Primary Purpose: Treatment Number of Participants With Serious Adverse Events Number of Participants With Adverse Events Change in Minimum Masking Level (MML) in Units of dB (Decibels) (and 2 more...) U. Iowa U. Buffalo UT Dallas
Commercial Lidocaine Patch as a Treatment for Ear-ringing Drug: Transdermal Lidocaine Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Functional Index (TFI) change at 4 week intervals up to a maximum time frame of 12 weeks UC Davis Department of Otolaryngology
Investigation of the NMDA Antagonist Ketamine as a Treatment for Tinnitus Drug: Ketamine Hydrochloride in saline Drug: Saline Allocation: Randomized Intervention Model: Crossover Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Change in GABA and Glutamate (Glx) levels in the auditory cortex derived from 3T Magnetic Resonance Spectroscopy Change in The Brief Psychiatric Rating Scale (BPRS) Change in Clinician Administered Dissociative Symptom Scale (CADSS) (and 9 more...) 1051 Riverside Drive
Effects of Caffeine in Tinnitus Dietary Supplement: caffeine Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Handicap Inventory Visual Analog Scale Faculdade de Medicina de Valença OTOSUL Otorrinolaringologia Sul-Fluminense
Tinnitus Treatment by Structured Cognitive Behavioral TherapyBehavioral: Cognitive behavioral therapy Other: Waiting group Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Validated tinnitus questionaire (TF Goebel and Hiller 1992); validated tinnitus change rating scale (TC, Zenner and de Maddalena 2005) Tinnitus loudness (TL), validated 6-point numeric verbal rating scale; tinnitus annoyance (TA), validated 8-point numeric verbal rating scale Tinnitus Care Center Tinnitus Care Center Dept. ORL, University of Tuebingen Private Practice
Hearing Aid Impact on ChronicTinnitus Patients Evaluated by Resting State PET. Device: hearing aid fitting Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment PET RESULTS Tinnitus Handicap Inventory (THI) Hearing Handicap Inventory for Adults (HHIA) Visual Analog Scale ( VAS) University of Sao Paulo
rTMS To The Dorsolateral Prefrontal Cortex For Patients With Subjective IdiopathicTinnitus . A Pilot Study Device: Repetitive Transcranial Magnetic Stimulation (rTMS), pilot study Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Average Change (Baseline-End of Treatment) Tinnitus Handicap Inventory (THI) Washington University School of Medicine
The Value of EMDR in the Treatment of Tinnitus Other: TRT / EMDR Behavioral: TRT / CBT Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Tinnitus Functional Index (TFI) Visual Analogue Scale (VAS) of loudness Tinnitus questionnaire (TQ) (and 4 more...) Antwerp University Hospital
Tinnitus Alleviation Via Sensory StimulationDevice: MuteButton sensory stimulation device Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Handicap Inventory (THI) Visual Analogue Scale (VAS) Tinnitus Loudness Matching (TLM) Minimum Masking Level (MML)
Transcranial Magnetic Stimulation for Tinnitus Device: repetitive transcranial magnetic stimulation (rTMS) Device: placebo rTMS Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Outcomes Assessor) Primary Purpose: Other Change in Tinnitus Functional Index (TFI) Score VA Portland Health Care System, Portland, OR
rTMS Bimodal Treatment ForTinnitus : A Pilot Study Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Adverse Events Change in Tinnitus Handicap Inventory Washington University School of Medicine
1 Tinnitus Alleviation Via Sensory Substitution Device: Mutebutton intervention Observational Model: Cohort Time Perspective: Retrospective Number of participants who achieve a clinically significant reduction in Tinnitus Handicap Inventory (THI) score Difference in mean Visual Analogue Scale (VAS) score from before after intervention Difference in mean Tinnitus Loudness Matching (TLM) score before and after intervention. Difference in mean Minimum Masking Level (MML) score intervention before and after intervention. Hermitage Medical Clinic, Lucan
Clinical Trial of Sound-Based Versus Behavioral Therapy forTinnitus Device: Desyncra Other: Cognitive Behavioral Therapy Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Change from baseline Tinnitus Questionnaire score VA Portland Health Care System, National Center for Rehabilitative Auditory Research
Exploring Voluntary Control ofTinnitus Observational Model: Cohort Time Perspective: Cross-Sectional Changes in brain neural activity between before and after tinnitus modulation as detected on functional connectivity MRI. Washington University School of Medicine
A Comparison of Two Psycho-educational Group Interventions for Tinnitus Patients Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Sourasky Medical Centre
Mindfulness-based Therapy in Chronic Tinnitus Behavioral: Mindfulness-based therapy Behavioral: Treatment after waiting time Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Change in tinnitus complaints as measured by the German version of the Tinnitus Questionnaire (TQ)(Baseline versus week 9) Change in rating scores of German versions of the Tinnitus Handicap Inventory (Hallam) (Baseline versus week 7) Change in rating scores of German versions of the Tinnitus Handicap Inventory (Hallam) (Baseline versus week 9) (and 10 more...) University of Regensburg - Dep. of Psychiatry
Efficacy of Treatment forTinnitus Other: Cognitive Behavioral Therapy Observational Model: Cohort Time Perspective: Retrospective Tinnitus-severity assessed with the Tinnitus-questionnaire (Goebel and Hiller 1998). Brief Symptom Inventory (BSI, Derogatis 1975) Beck Depression Inventory (BDI, Beck 1961) Noise Sensitivity Questionnaire [Nelting 2004]
Treatment Evaluation of Neuromodulation for Tinnitus (TENT-A) Device: PS1 Device: PS2 Device: PS3 Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Device Feasibility Tinnitus Functional Index Tinnitus Handicap Inventory University Hospital Regensburg St. James's Wellness Trust Clinical Research Facility
Repetitive Transcranial Magnetic Stimulation (rTMS) for Tinnitus Device: transcranial magnetic stimulation (Magstim rapid2) Device: sham stimulation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Outcomes Assessor) Primary Purpose: Treatment Tinnitus severity with the Tinnitus Questionnaire Tinnitus Handicap Inventory Beck Depression Inventory (and 3 more...) University Medical Center Utrecht
Internet-based CBT forTinnitus Behavioral: Cognitive behavioral therapy Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Subjective improvement of tinnitus Beck's depression survey Post-traumatic Stress Disorder civilian survey (and 2 more...) University of California Irvine Medical Center
Variability of Tinnitus Characterization Tools and Investigation of Audiovisual Integration in Tinnitus Perception Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Other Change in Minimal Masking Level Change in Tinnitus Rating (0-10, 10 being worst) Change in Tinnitus Functional Index Questionnaire Score (and 2 more...) University of Minnesota, Nils Hasselmo Hall, 6-105
Detection of Emotions in a Spoken Language AmongTinnitus Patients Observational Model: Case Control Time Perspective: Prospective Wolfson Medical Centre
Evaluation of Low Dose Laser in Treatment of Tinnitus Radiation: Low dose laser Radiation: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment
ICCAC-ToNF & Tinnitus Other: tomographic EEG Neurofeedback Training Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Change from Baseline in Tinnitus symptoms assessed by questionnaires Change from Baseline in frequency band EEG-activity in the auditory cortex, insula & dorsal anterior cingulate cortex brain structure (volume, surface area) of the three regions of interest as predictor for training success. University Hospital Zurich, Division of Otorhinolaryngology ORL
Combined rTMS and Relaxation in Chronic Tinnitus Device: Left DLPFC Butterfly Coil Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Number of treatment responders (TQ reduction > 5, contrast Baseline versus end of treatment) Change of tinnitus severity as measured by the Tinnitus Questionaire of Goebel&Hiller Change of tinnitus severity as measured by the Tinnitus Handicap Inventory (THI) (and 4 more...) University of Regensburg - Dept of Psychiatry
The Effect of Tinnitus Retraining Therapy on Subjective and Objective Measures of Chronic Tinnitus Behavioral: Tinnitus retraining therapy Device: Sound therapy Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Change in objective measure of tinnitus loudness using psychoacoustic matching task Change in subjective handicap rating of tinnitus using a standardized questionnaire Change in subjective ratings of tinnitus loudness, annoyance and awareness Southern Illinois University School of Medicine
Neuro-Music Therapy for Recent Onset Tinnitus : Evaluation of a Therapy Concept Behavioral: Neuro-Music Therapy immediately Behavioral: Neuro-Music Therapy after waiting time Behavioral: Music-therapeutical stress management coaching Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Questionnaire (TQ, Goebel and Hiller 1998) total score change from baseline to end of treatment Tinnitus-Beeinträchtigungs-Fragebogen (TBF-12, Greimel et al. 2000) total score change from baseline to end of treatment change in tinnitus frequency (and 3 more...) German Center for Music Therapy Research
Treatment of Chronic Bothersome Tinnitus Using Cognitive Training and D-cycloserine Behavioral: Cognitive Training Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Change from baseline in Tinnitus Handicap Inventory (THI) Change in Neurocognitive assessment score Washington University School of Medicine
A Study on the Effect of Cilostazol in Patients With Chronic Tinnitus Drug: Cilostazol Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary Purpose: Treatment Change of the tinnitus handicap inventory (THI) score Changes of Quality of Life (SF-36) score Change of the visual analogue scale (VAS) score Asan Medical Center
Tinnitus Treatment Using a Smartphone ApplicationBehavioral: Tinnitus application Allocation: Randomized Intervention Model: Crossover Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Handicap Inventory score Sourasky Medical Center
Clinical Trial of Acamprosate for Tinnitus Drug: Acamprosate Drug: Placebo Allocation: Randomized Intervention Model: Crossover Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Tinnitus Handicap Index Tinnitus Functional Index Tinnitus loudness score on visual numerical scale Depression Inventory Psychoacoustic measures of tinnitus OHSU
Internet-based Guided Self-help for Chronic Tinnitus Behavioral: Internet-based guided self-help for tinnitus Other: Internet discussion forum Allocation: Randomized Intervention Model: Crossover Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Handicap Inventory (THI; Newman, Jacobson, & Spitzer, 1996; German version: Kleinjung et al., 2007) MINI-Tinnitus Questionnaire (Mini-TQ; Hiller & Goebel, 2004) Hospital Anxiety and Depression Scale (HADS-D; Zigmond & Snaith, 1983; German version: Herrmann-Lingen, Buss, & Snaith, 2005) (and 12 more...) Department of Behavioural Sciences and Learning, Linkoeping University
Acupuncture as a Treatment for Tinnitus Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Ethylcysteinate dimer single-photon emission computer tomography (99mTc-ECD SPECT) Tinnitus Handicap Inventory (THI) Visual Analog Scale (VAS) (and 2 more...)
Neuro-Music-Therapy for Patients With Chronic Tinnitus - a Controlled Clinical Trial Behavioral: Neuro-Music-Therapy according to the Heidelberg Model Behavioral: Counselling Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Tinnitus Questionnaire (TQ, Goebel and Hiller 1998) Total Score Change From Baseline to End of Treatment Change in Tinnitus Frequency (Pitch), Obtained at Admission (Pre) and After Therapy Intervention (Post) German Center for Music Therapy Research
Influence of Treatment Duration and Stimulation Frequency on rTMS in ChronicTinnitus Other: standard multisite four weeks Other: high-frequency multisite four weeks Other: standard multisite two weeks Other: high-frequency multisite two weeks Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment change in tinnitus questionnaire change in tinnitus handicap inventory change in tinnitus numeric rating scales (and 3 more...) University of Regensburg- Dept of Psychiatry
The Effects of Compensatory Auditory Stimulation and Transcranial Direct Current Stimulation on Tinnitus Perception Other: Compensatory auditory stimulation Device: transcranial direct current stimulation Other: Combined CAS and tDCS Other: Sham stimulation Allocation: Randomized Intervention Model: Crossover Assignment Masking: Single (Participant) Primary Purpose: Treatment Reduction in minimum masking levels Reduction in tinnitus percept as assessed via the visual analog test of tinnitus loudness
Efficacy, Safety, Tolerability of Neramexane in Patients With Subjective Tinnitus Drug: Neramexane mesylate Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Absolute Change in TBF-12 (Tinnitus Handicap Inventory-12) Total Score from Baseline. Absolute Change in TSSw (Tinnitus Severity Scale - One Week Version) Total Score from Baseline. TBF-12 Total Score: Change from Baseline (and 7 more...) Horizon Clinical Research Associates PLLC Phoenix Clinical Paradigm Clinical Research (and 73 more...)
Daily Bitemporal Low-frequency Transcranial Random Noise Stimulation inTinnitus (tRNS2-tin) Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment number of treatment responders change in tinnitus questionnaire change in tinnitus handicap inventory change in tinnitus numeric rating scales University of Regensburg - Deptartment of Psychiatry
Processing Speed as an Objective Measure of Tinnitus Time Perspective: Prospective Washington University School of Medicine
Combined Low Frequency Frontal and Temporal rTMS Treatment in Chronic Tinnitus Device: Combined frontal and temporal rTMS Device: Temporal low frequency rTMS Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Change of tinnitus severity as measured by the Tinnitus Questionnaire of Goebel and Hiller Change of tinnitus severity as measured by the Tinnitus Questionaire of Goebel&Hiller, Tinnitus Handicap Inventory (THI), Tinnitus Severity Scale and TBF-12 Change of depressive symptoms as measured by the Beck Depression Inventory (BDI) Change in quality of life as measured by the WHOQoL University of Regensburg - Dept of Psychiatry
Acoustic Stimulation Paired With Body and Cortical Stimulation for ModulatingTinnitus Device: noise sound stimulation (Tucker-Davis Technologies) Device: body electrical stimulation (Digitimer device) Device: transcranial magnetic stimulation (Magstim) Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Other Change in Tinnitus Functional Index Questionnaire Score Change in Minimal Masking Level Change in Tinnitus Handicap Inventory Questionnaire Score (and 4 more...) Nils Hasselmo Hall, 6-105
AM-101 in the Treatment of Acute Tinnitus 3 Drug: AM-101 Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Efficacy endpoint - alternate primary efficacy endpoints: Tinnitus Functional Index (TFI) Efficacy endpoint - alternate primary efficacy endpoints: Patient-reported Tinnitus loudness on a Numerical Rating Scale (TLQ NRS loudest) Safety endpoint: Hearing threshold (and 7 more...) Please check the study webpage below for a study site list
Effect of rTMS on Resting State Brain Activity in Tinnitus Device: Repetitive Transcranial Magnetic Stimulation (rTMS) - ACTIVE Device: Repetitive Transcranial Magnetic Stimulation (rTMS) - SHAM Allocation: Randomized Intervention Model: Single Group Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Change in tinnitus perception, as measured over time using a subjective visual analog rating scale Change in Beck's Depression Inventory (BDI) Change in Tinnitus Handicap Inventory (THI) EEG measures of spectral power and coherence University of Arkansas for Medical Sciences
Tinnitus Retraining Therapy TrialDevice: Conventional sound generator (SG) Device: Placebo sound generator (placebo SG) Behavioral: Standard of Care (SC) Behavioral: Directive Counseling (DC) Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Change in Tinnitus Questionnaire (TQ) From Baseline to 3, 6, 12, and 18 Months Change in Tinnitus Functional Index (TFI) From Baseline to 3, 6, 12, and 18 Months Change in Tinnitus Handicap Inventory (THI) Score From Baseline to 3, 6, 12, and 18 Months Follow-up (and 17 more...) Naval Hospital Camp Pendleton Naval Medical Center David Grant Medical Center (and 3 more...)
Hearing Aids With "Notched Amplification" for the Treatment of Chronic Tinnitus Device: Notched filtering (verum) Device: No filtering (placebo) Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment Mini Tinnitus Questionnaire (Mini-TQ12 of Göbel&Hiller) Adverse events Improvement of tinnitus measured by changes in the Tinnitus Questionnaire (TQ of Goebel&Hiller) (and 7 more...) University of Regensburg - Dept of Psychiatry and ENT Dept.
Comparison of an Internet-based Guided Self-help and a Group Therapy for ChronicTinnitus Behavioral: Internet-based guided self-help for tinnitus Behavioral: Cognitive-behavior group therapy for tinnitus Other: Internet discussion forum Allocation: Randomized Intervention Model: Crossover Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Handicap Inventory (THI; Newman, Jacobson, & Spitzer, 1996; German version: Kleinjung et al., 2007) MINI-Tinnitus Questionnaire (Mini-TQ; Hiller & Goebel, 2004) Hospital Anxiety and Depression Scale (HADS-D; Zigmond & Snaith, 1983; German version: Herrmann-Lingen, Buss, & Snaith, 2005) (and 12 more...) Department of Clinical Psychology and Psychotherapy, Johannes Gutenberg University Mainz
Repetitive Transcranial Magnetic Stimulation for Chronic Subjective Tinnitus Procedure: Repetitive Transcranial Magnetic Stimulation Procedure: Sham stimulation Drug: Ginkgo Biloba Extract Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Tinnitus Reaction Questionnaire (TRQ) Tinnitus Handicap Questionnaire (THQ) Tinnitus Handicap Inventory (THI) (and 2 more...) University Hospital Ostrava
Resting-State Neural Connectivity in Patients With Subjective Tinnitus Without Bother Observational Model: Case-Only Time Perspective: Cross-Sectional Recruit 20 participants and have them undergo both neuro-cognitive and neuro-imaging testing. Washington University, Center for Clinical Studies
The Effect of Physiotherapy on Cervicogenic SomaticTinnitus Allocation: Randomized Intervention Model: Crossover Assignment Masking: Single (Participant) Primary Purpose: Treatment Change in Tinnitus Functional Index University Hospital of Antwerp
AM-101 in the Treatment of Post-Acute Tinnitus 2 Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Hearing threshold Adverse events and serious adverse events Investigational site
Tinnitus Treatment With Piribedil Guided by Acoustic Otoemissions and ElectrocochleographyAllocation: Randomized Intervention Model: Crossover Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary Purpose: Treatment THI - Tinnitus Handicap Inventory VAS - Visual Analog Scale OTOSUL,Otorrinolaringologia Sul-Fluminense
Deep TMS of the Left Auditory Cortex Using the HMCIPCC Coil, in the Treatment of Patients With Tinnitus . Device: Deep Transcranial Magnetic Stimulation Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment TQ - Tinnitus questionnaire VAS (100 - worst possible tinnitus related discomfort; 0 - wellness) Wolfson Hospital
Pilot Study of Deep Brain Stimulation (DBS) in Area LC for Chronic Tinnitus Device: Deep Brain Stimulation (DBS) Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Tinnitus Functional Index (TFI) score change San Francisco Veterans' Administration Medical Center
Gameplay as a Source of Intrinsic Motivation in a Randomized Controlled Trial of Auditory Training for Tinnitus Other: reactive auditory training Other: Interactive auditory training Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Tinnitus Handicap Questionnaire Tinnitus Handicap Inventory psychoacoustic measures of tinnitus NIHR Nottingham Hearing Biomedical Research Unit
AM-101 in the Treatment of Post-Acute Tinnitus 1 Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Frequency of Subjects With a Deterioration of Hearing Threshold at Day 35 (Air Conduction) Frequency of Subjects With a Deterioration of Hearing Threshold at Day 119 (Air Conduction) Frequency of Subjects With a Deterioration of Hearing Threshold at Day 203 (Air Conduction) (and 3 more...) Medpace
AM-101 in the Treatment of Acute Tinnitus 2 Drug: AM-101 Drug: Placebo Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Efficacy: Change in Patient-reported Tinnitus Loudness Questionnaire (TLQ) Improvement From Baseline to Follow up Visit 3 (FUV3) Co-Primary Efficacy: Improvement in Tinnitus Functional Index (TFI) Total Score From Baseline to FUV3 Safety: Frequency of Subjects With Deterioration of Hearing at Follow up Visit 2 (FUV2) Medpace
The Study of Wuling Capsule in Treatment Chronic Tinnitus Drug: Wuling Capsule Drug: Oryzanol Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Xijing Hospital
The Effect of Transcranial Direct Current Stimulation (tDCS) in Addition to Tinnitus Retraining Therapy (TRT) for Treatment of Chronic Tinnitus Patients Device: transcranial direct current stimulation (tDCS) Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double Primary Purpose: Treatment Tinnitus Functional Index (TFI) Hyperacusis Questionnaire Hospital Anxiety and depression Scale (and 4 more...) University hospital of Antwerp
Task-Based Functional MRI (fMRI) in Patients With Severely Bothersome Tinnitus Observational Model: Cohort Time Perspective: Prospective Perform task based functional imaging on severely bothered tinnitus patients Perform neurocognitive testing on severely bother tinnitus patients 
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου