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Σάββατο 13 Ιανουαρίου 2018

An integrated fuzzy-based advanced eutrophication simulation model to develop the best management scenarios for a river basin

Abstract

Assessment of water quality status of a river with respect to its discharge has become prerequisite to sustainable river basin management. The present paper develops an integrated model for simulating and evaluating strategies for water quality management in a river basin management by controlling point source pollutant loadings and operations of multi-purpose projects. Water Quality Analysis and Simulation Program (WASP version 8.0) has been used for modeling the transport of pollutant loadings and their impact on water quality in the river. The study presents a novel approach of integrating fuzzy set theory with an "advanced eutrophication" model to simulate the transmission and distribution of several interrelated water quality variables and their bio-physiochemical processes in an effective manner in the Ganges river basin, India. After calibration, simulated values are compared with the observed values to validate the model's robustness. Fuzzy technique of order preference by similarity to ideal solution (F-TOPSIS) has been used to incorporate the uncertainty associated with the water quality simulation results. The model also simulates five different scenarios for pollution reduction, to determine the maximum pollutant loadings during monsoon and dry periods. The final results clearly indicate how modeled reduction in the rate of wastewater discharge has reduced impacts of pollutants in the downstream. Scenarios suggesting a river discharge rate of 1500 m3/s during the lean period, in addition to 25 and 50% reduction in the load rate, are found to be the most effective option to restore quality of river Ganges. Thus, the model serves as an important hydrologic tool to the policy makers by suggesting appropriate remediation action plans.



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Scholar : Journal of Otolaryngology and Ophthalmology of Shandong University, Year 2017, Issue 06 -New Issue Alert.



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In this issue:

Borderline thyroid tumor in the new World Health Organization classification of 2017 (2017年新版WHO甲状腺交界性肿瘤解读)
LIU Zhiyan
...... page:1-4
Interpretation of the eighth edition of thyroid cancer tumor-node-metastasis staging by American Joint Committee on Cancer (美国癌症联合委员会第8版甲状腺癌TNM分期解读)
QIU Jie, ,SUN Shasha, ,SUN Yan
...... page:5-8
Identification and protection of the parathyroid glands during thyroidectomy (甲状腺手术中甲状旁腺的识别和保护)
ZHONG Qi
...... page:9-11
Optimal management of differentiated thyroid carcinoma in children (儿童甲状腺癌的规范化诊治)
XU Shuhang, ,LI Chunrui, ,LIU Chao
...... page:12-15
Standardization of the diagnosis and treatment of anaplastic thyroid carcinoma (甲状腺未分化癌的规范化治疗)
SUN Bin, ,GUO Bomin, ,KANG Jie, ,DENG Xianzhao, ,WU Bo, ,FAN Youben
...... page:16-20
Relationship between thyroid cancer and hematological components of the systemic inflammatory response (甲状腺癌与外周静脉血炎性相关指标)
PUBU Ciren, ,LIU Jifeng, ,BA Luo
...... page:21-24
xin xi dong tai (信息动态)

...... page:24,73
Clinical characteristics and treatment of differentiated thyroid carcinoma in children (儿童分化型甲状腺癌的临床特征及治疗体会)
SUN Guochen, ,SUN Yan, ,ZHANG Hong, ,WANG Baowei
...... page:25-28
Expression and clinical significance of Heparanase and D2-40 in pediatric thyroid carcinoma (乙酰肝素酶和D2-40在儿童甲状腺癌中的表达及临床意义)
PAN Yongjie, ,PANG Wenhui, ,SUN Guochen, ,SUN Yan, ,ZHANG Hong
...... page:29-32
A case of recurrent laryngeal nerve schwannoma misdiagnosed as a thyroid tumor (误诊为甲状腺肿物的颈部喉返神经神经鞘瘤一例)
WANG Zhixiang, ,XUE Kai, ,WEI Ning, ,HAN Shuang, ,JIN Chunshun
...... page:33-35
Intrathoracic vagal goiter:a report of one case and a literature review (胸内迷走甲状腺肿一例并文献复习)
ZHANG Zhuan, ,LIU Tao, ,ZHOU Chang-ming, ,MA Lu
...... page:36-38
A novel PAX3 mutation causing type I Waardenburg syndrome (新型PAX3基因突变导致Waardenburg I型综合征)
XU Xinbo, ,MA Xiaojie, ,YAN Tao, ,HAN Xiao, ,ZHANG Hanbing
...... page:39-41,52
Curative effect of postural restriction on benign paroxysmal positional vertigo after manual reduction (体位限制对手法复位后良性阵发性位置性眩晕的疗效观察)
LI Guifang, ,WANG Chunhua, ,ZHANG Shuzhen
...... page:42-45
Expression of chemokine ligand 27 in secondary middle ear cholesteatoma (继发性胆脂瘤中CCL27的定位及检测)
ZHANG Menglu, ,LI Yongtuan
...... page:46-48
Endoscopic anterior prelacrimal recess surgery for treatment of inverted papillomas (鼻内镜下泪前隐窝入路治疗上颌窦内翻性乳头状瘤的疗效分析)
CUI Xiao, ,YAN Aihui
...... page:49-52
Effect of obstructive sleep apnea-hypopnea syndrome on blood glucose, serum lipid, and C-reactive protein levels (阻塞性睡眠呼吸暂停低通气综合征对血糖、血脂及C反应蛋白的影响)
REN Tao, ,TANG Yijun, ,WANG Meifang, ,LIU Yan, ,QIAN Xin
...... page:53-57
Treatment of pharyngeal stenosis following uvulopalatopharyngoplasty with coblation (等离子辅助悬雍垂腭咽成形术后重度咽狭窄的治疗)
HUO Hong, ,LI Wuyi, ,WANG Jian, ,YANG Dahai, ,JIN Xiaofeng, ,TIAN Xu, ,NIU Yanyan
...... page:58-61
Predictors of difficult airway in patients with obstructive sleep apnea-hypopnea syndrome during general anesthe- sia (阻塞性睡眠呼吸暂停低通气综合征患者手术麻醉中困难气道发生的因素预测)
LI Ling, ,WANG Chunling, ,ZHANG Li, ,LI Yanzhong
...... page:62-67
Comparison of the curative effect of CO2 laser microsurgery and conventional microsurgery for vocal polyp resec- tion (CO2激光显微手术与传统显微手术切除声带息肉疗效比较)
HAO Yan, ,LI Dongcai, ,LAN Jianping
...... page:68-70
Improvement of pharyngalgia in 8 cases of styloid process syndrome by surgical shortening of the styloid proces- ses (茎突截短术改善茎突综合征咽痛症状八例)
QIU Jibing, ,YIN Yanze, ,MA Jing
...... page:71-73
Delayed corneal wound healing is related to impaired IGF-1 expression in diabetic rats (糖尿病大鼠角膜上皮创伤愈合中IGF-1的表达)
ZHANG Ying, ,CHEN Hong-mei, ,WU Xinyi
...... page:74-78
Outcomes of sinus balloon catheter dilation in treatment of pediatric chronic rhinosinusitis: a systematic review and meta-analysis (鼻窦球囊扩张治疗儿童慢性鼻窦炎的系统评价及Meta分析)
LIN Xing, ,LIN Zongtong, ,SHEN Ling
...... page:79-86
Diagnosis and treatment of upper airway cough syndrome in children (儿童上气道咳嗽综合征临床诊疗现状)
JING Shanglin
...... page:87-91
Common susceptibility genes of primary open-angle glaucoma (原发性开角型青光眼易感基因研究进展)
ZHAO Dongdong, ,WANG Yi, ,GAO Jianlu
...... page:92-96
Traumatic cerebrospinal fluid rhinorrhea complicated with headache and dizziness treated by traditional Chinese medicine:one case report (外伤性脑脊液鼻漏合并头痛头晕的中医治疗一例报告)
LI Ping
...... page:97
Diagnosis and treatment of the double internal fistula of incomplete third branchial fistulas and literature review (双内瘘口型不完全性第三鳃裂瘘诊治分析并文献复习)
ZHANG Yong, ,LI Yifei, ,CHENG You, ,JI Han
...... page:98-100


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Scholar : Journal of Clinical Stomatology, Year 2017, Issue 12 -New Issue Alert.



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In this issue:

xia zuo duo sheng di si mo ya 1 li (下颌多生第四磨牙1例)
WANG Lingxiao, ,DAN Zhaochen, ,LI Jun, ,GAO Zhenhua
...... page:706,763
The regulatory effect of over-expression of Formyl Peptide Receptor-2 on dendritic cell maturation and chemo-taxis (过表达Fpr2对树突状细胞成熟和趋化功能的调控作用)
ZHANG Zhou, ,XU Qing-an
...... page:707-711
The effects of surface treatments by different chemical solvents on the bond strength of glass fiber post with res-in cement (不同化学溶剂的桩表面处理对玻璃纤维桩与树脂水门汀粘接强度的影响)
SHENG Min, ,SHI Ning
...... page:711-714
Expression of DKK1,SFRP1,Runx2 and Osteocalcin in experimental periapical lesions in mice (根尖周炎模型小鼠DKK1、SFRP1及骨形成相关分子Runx2、Osteocalcin的表达变化)
ZHOU Wei-jun, ,CHE Ying-lin, ,YANG Rui-kun, ,DENG Qiu-yan
...... page:715-719
The expression and clinical significance of microRNA-146a in oral squamous cell carcinoma (microRNA-146a在口腔鳞状细胞癌中的表达及临床意义)
DOU Wei-wei, ,YUE Cong-lei, ,LIU Hong-wei, ,XU Ning, ,LV Qin, ,GAO De
...... page:719-722
The promoting effect of exosome from plasma to bFGF and angiogenesis in vitro (血浆外泌体上调bFGF促体外微血管网形成的研究)
GU Xia, ,YAO Yang, ,HUANG Bo, ,TANG Hai-Yang, ,LIAO Wen, ,GONG Ping
...... page:723-726
The study of surgical approach for the reposition and rigid fixation on zygomatic complexfractures (两种入路下颧骨复合体骨折切开复位内固定的临床疗效观察)
DONG Zheng-mou, ,NIE Xin, ,CHEN Yu-bing, ,HE Hai-tao, ,LIU Lu-chuan, ,WEN Xiu-jie
...... page:727-730
Effect of probiotics combined with scaling and root planing in the treatment of periodontitis:a meta-analysis (益生菌制剂辅助刮治和根面平整对牙周炎疗效的Meta分析)
GE Chun-cheng, ,YU zhou-qing, ,TONG Guo-yong, ,XU Jia
...... page:731-734
Effect of oral comprehensive intervention on caries prevention of 6 ~ 12 years old pupils in Yichang City of Hubei Province (湖北宜昌市6~12岁儿童口腔综合干预防龋6年效果评价)
XIE Gui-ying, ,ZHAO Hua, ,ZHENG Cheng, ,FU Xin, ,ZHOU Li-xin, ,ZENG Li-jun, ,XIAO Wei, ,LI Zi-chao
...... page:735-739
A randomized controlled clinical trial:the effectiveness of tizanidine to myofascial pain (替扎尼定治疗肌筋膜痛有效性的随机临床对照研究)
LI Hao-sen, ,LI Wen-qiang, ,LIU Tian
...... page:739-741
Comparison of clinical effects of aesthetic crown lengthening with two different procedures (两种不同程序美学牙冠延长术临床疗效对比)
WANG Ying-ying, ,LUO Lin-feng
...... page:742-745
Superselective submental island flap for repairing the postoperative defect of oropharyngeal carcinoma (超选择颏下岛状瓣在口咽癌术后缺损修复中的应用)
CHEN Jing-xin, ,DENG Wei, ,ZHONG Shao-bo, ,FU Liang-bin, ,HU Guang-wei, ,WANG Tao
...... page:745-747
The performance of VITA Easyshade compact (VITA Easyshade电脑比色仪的比色性能研究)
XING Ya-fei, ,WANG Yi-qing, ,MA Shu-qi, ,ZHOU Qin
...... page:748-751
bing xing gan yan bing du gan ran yu bian ping tai zuo de guan xi (丙型肝炎病毒感染与扁平苔藓的关系)
ZHOU Kecong
...... page:752-756
zhong zhi ti duo gong neng kang jun tu ceng de fen lei ji jin zhan (种植体多功能抗菌涂层的分类及进展)
ZHANG Lanxin, ,WANG Qin, ,WANG Yingxue, ,CHEN Zhuozuo, ,WANG Wei
...... page:756-758
ru ya zao shi hou jian xi bao chi qi de xuan ze ji ying yong (乳牙早失后间隙保持器的选择及应用)
ZHAO Jiali
...... page:759-762


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High stiffness polymer composite with tunable transparency

Publication date: Available online 12 January 2018
Source:Materials Today
Author(s): Peter Samora Owuor, Varun Chaudhary, Cristiano F. Woellner, V Sharma, R.V. Ramanujan, Anthony S. Stender, Matias Soto, Sehmus Ozden, Enrique V. Barrera, Robert Vajtai, Douglas S. Galvão, Jun Lou, Chandra Sekhar Tiwary, Pulickel M. Ajayan
Biological materials are multifunctional performing more than one function in a perfect synergy. These materials are built from fairly simple and limited components at ambient conditions. Such judicious designs have proven elusive for synthetic materials. Here, we demonstrate a multifunctional phase change (pc) composite from simple building blocks, which exhibits high stiffness and optical transmittance control. We show an increase of more than one order of magnitude in stiffness when we embed paraffin wax spheres into an elastomer matrix, polydimethylsiloxane (PDMS) in a dynamic compression test. High stiffness is mainly influenced by presence of microcrystals within the wax. We further show fast temperature-controlled optical switching of the composite for an unlimited number of cycles without any noticeable mechanical degradation. Through experimental and finite element method, we show high energy absorption capability of pc-composite. Based on these properties, the pc-composite could be used as an effective coating on glasses for cars and windows. This simple approach to multi-functionality is exciting and could pave way for designs of other multifunctional materials at the macro-scale.

Graphical abstract

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Heterogeneous catalysis by gold and gold-based bimetal nanoclusters

Publication date: Available online 12 January 2018
Source:Nano Today
Author(s): Jianbo Zhao, Rongchao Jin
Gold and gold-based bimetallic catalysts have shown great potential for many important chemical transformation reactions owing to their good activity and high selectivity under relatively mild conditions. However, elucidating their structure-property relationships remains a major challenge because of size distributions and ill-defined structures (i.e. structural heterogeneity) of conventional nanoparticle catalysts. Recently, controlled synthesis of homogold and gold-based bimetal nanoclusters with precise atom numbers have been accomplished, and more importantly their atomic structures have been elucidated, which provide new model systems for understanding the catalytic behavior at the atomic level. Due to their ultra-small size, gold and bimetal nanoclusters exhibit unique properties, which contribute to novel catalysts or precatalysts for many chemical reactions. Herein, we review the recent progress in the catalytic research of atomically precise gold and gold-based bimetal nanoclusters. Specifically, this review covers the application of nanoclusters with or without ligands as catalysts for reactions such as selective oxidation, selective hydrogenation, C–C coupling and photocatalysis. Finally, we provide some future perspectives about metal nanocluster catalysis.

Graphical abstract

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Hydrogeochemical processes and influence of seawater intrusion in coastal aquifers south of Chennai, Tamil Nadu, India

Abstract

Seawater intrusion promotes the salinity of groundwater, and it poses a great environmental impact on a global scale. The present study was carried out to determine the hydrogeochemical processes and influence of seawater intrusion in the coastal aquifers using geophysical, geochemical, and stable isotope techniques. The true resistivity value ranges from 0.5 to 8008.5 Ω-m which has been measured using vertical electrical sounding (VES) based on the Schlumberger method. About 33 groundwater samples were collected during post-monsoon (POM) (January 2012) and pre-monsoon (PRM) (June 2012) seasons from open and bore wells and were analyzed for major ions and stable isotopes. EC, Na+, and Cl were high in groundwater of wells near salt pan, the Buckingham Canal, and backwater regions. Around 45% of the groundwater of this study area is of Na+-Cl type due to salinisation. Reverse ion exchange and silicate weathering are the dominant processes controlling the geochemistry of groundwater. Saturation indexes (SI) of halite (SIhalite) and gypsum (SIgypsum) versus sulfate show an increasing trend line from > 0 to < 0, which implies higher dissolution of minerals and hints increasing salinization during both seasons. The value of Na+/Cl ranges between 0.7 and 2.4 (POM) and from 0.6 to 2.8 (PRM). The molar ratio suggested that around 25% of the groundwater samples are with values similar to those of seawater. Further, the groundwater is also affected by saline backwater, salt pan activities, and Buckingham Canal. Some locations are also are affected by anthropogenic, agricultural activities and geochemical processes. Heavy stable isotopes were found to be dominant in the coastal region due to seawater intrusion. Stable isotopes of δ18O range from − 5.6 to − 2.9‰ during both periods. About 201 km2 of this area is affected by salinization. It is necessary to reduce pumping and plan for physical barriers to create freshwater ridges for controling the seawater intrusion.



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Exposure to nanoscale and microscale particulate air pollution prior to mining development near a northern indigenous community in Québec, Canada

Abstract

This study serves as a baseline characterization of indoor and outdoor air quality in a remote northern indigenous community prior to the start of a major nearby mining operation, including measurements of nanoparticles, which has never been performed in this context before. We performed aerosol sample collection and real-time aerosol measurements at six different locations at the Cree First Nation of Waswanipi and the Montviel campsite, located 45 km west of the Cree First Nation of Waswanipi, in the south of the Nord-du-Québec region. High concentrations of airborne nanoparticles (up to 3.98 × 104 ± 8.9 × 103 cm−3 at 64.9-nm midpoint particle diameter) and fine particles (up to 1.99 × 103 ± 1.6 × 102 cm−3 at 0.3-μm midpoint particle diameter) were measured inside a residential home, where we did not find any ventilation or air filtration systems. The most abundant particle sizes by mass were between 0.19 and 0.55 μm. The maximum concentration of analyzed heavy metals was detected at the d50 cut-off particle size of 0.31 μm; and the most abundant heavy metals in the aerosol samples were Al, Ba, Zn, Cu, Hg, and Pb. We concluded that the sources of the relatively high indoor particle concentrations were likely laundry machines and cooking emissions in the absence of a sufficient ventilation system. However, the chemical composition of particles resulting from mining activities is expected to be different from that of the aerosol particles from indoor sources. Installation and proper maintenance of sufficient ventilation and air filtration systems may reduce the total burden of disease from outdoor and indoor air pollution and remediate infiltrated indoor particulate pollution from the mining sources as well.



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Ecotoxicity thresholds for ametryn, diuron, hexazinone and simazine in fresh and marine waters

Abstract

Triazine and urea herbicides are two groups of photosystem II inhibiting herbicides frequently detected in surface, ground and marine waters. Yet, there are few water quality guidelines for herbicides. Ecotoxicity thresholds (ETs) for ametryn, hexazinone and simazine (triazine herbicides) and diuron (a urea herbicide) were calculated using the Australian and New Zealand method for deriving guideline values to protect fresh and marine ecosystems. Four ETs were derived for each chemical and ecosystem that should theoretically protect 99, 95, 90 and 80% of species (i.e. PC99, PC95, PC90 and PC80, respectively). For all four herbicides, the phototrophic species were significantly more sensitive than non-phototrophic species, and therefore, only the former data were used to calculate the ETs. Comparison of the ET values to measured concentrations in 2606 samples from 15 waterways that discharge to the Great Barrier Reef (2011–2015) found three exceedances of the simazine PC99, regular exceedances (up to 30%) of the PC99 in a limited number of rivers for ametryn and hexazinone and frequent (> 40%) exceedances of the PC99 and PC95 ETs in at least four waterways for diuron. There were no exceedances of the marine ETs in inshore reef areas. Further, ecotoxicity data are required for ametryn and hexazinone to fresh and marine phototrophic species, for simazine to marine phototrophic species, for tropical phototrophic species, repeated pulse exposures and long-term (2 to 12 months) exposures to environmentally relevant concentrations.



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Efficient degradation of triclosan by an endophytic fungus Penicillium oxalicum B4

Abstract

Triclosan (TCS), a widely used antimicrobial and preservative agent, is an emerging contaminant in aqueous and soil environment. Microbial degradation of TCS has not been reported frequently because of its inhibition of microbe growth. To explore the new microbial resources for TCS biodegradation, fungal endophytes were isolated and screened for the degradation potential. The endophytic strain B4 isolated from Artemisia annua L. showed higher degradation efficiency and was identified as Penicillium oxalicum based on its morphology and ITS sequences of ribosomal DNA. In both medium and synthetic wastewater, TCS (5 mg/L) was almost completely degraded within 2 h by the strain B4. The high capacity of TCS uptake (127.60 ± 8.57 mg/g dry weight, DW) of fungal mycelium was observed during the first 10 min after TCS addition. B4 rapidly reduced initial content (5.00 mg/L) of TCS to 0.41 mg/L in medium in 10 min. Then, the accumulation of TCS in mycelium was degraded from 0.45 to 0.05 mg/g DW after 1-h treatment. The degradation metabolites including 2-chlorohydroquinone, 2, 4-dichloropheno, and hydroquinone were found to be restrained in mycelia. The end products of the biodegradation in medium showed no toxicity to Escherichia coli. The new characteristics of high adsorption, fast degradation, and low residual toxicity highlight the potential of endophytic P. oxalicum B4 in TCS bioremediation.



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Variability and reliability of POP concentrations in multiple breast milk samples collected from the same mothers

Abstract

Risk assessment of infant using a realistic persistent organic pollutant (POP) exposure through breast milk is essential to devise future regulation of POPs. However, recent investigations have demonstrated that POP levels in breast milk collected from the same mother showed a wide range of variation daily and monthly. To estimate the appropriate sample size of breast milk from the same mother to obtain reliable POP concentrations, breast milk samples were collected from five mothers living in Japan from 2006 to 2012. Milk samples from each mother were collected 3 to 6 times a day through 3 to 7 days consecutively. Food samples as the duplicated method were collected from two mothers during the period of breast milk sample collection. Those were employed for POP (PCBs, DDTs, chlordanes, and HCB) analysis. PCB concentrations detected in breast milk samples showed a wide range of variation which was maximum 63 and 60% of relative standard deviation (RSD) in lipid and wet weight basis, respectively. The time course trend of those variations among the mothers did not show any typical pattern. A larger amount of PCB intake through food seemed to affect 10 h after those concentrations in breast milk in lipid weight basis. Intraclass correlation coefficient (ICC) analyses indicated that the appropriate sample size for good reproducibility of POP concentrations in breast milk required at least two samples for lipid and wet weight basis.



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Sb content dependent thermoelectric properties of the p-type ZnO:Sb films fabricated by oxidation method

Publication date: 1 May 2018
Source:Applied Surface Science, Volume 439
Author(s): Guojian Li, Xiao Lin, Shiying Liu, Baohai Jia, Qiang Wang
It is important to fabricate stable p-type ZnO:Sb thermoelectric (TE) films for the p-n homojunction TE devices that convert waste heat directly into electricity. In this study, the ZnO:Sb films with different Sb contents were prepared by oxidizing evaporated Zn-Sb films in oxygen. The film with a high Sb content (5.32%) is easy to form Zn4Sb3 and ZnSb compound in the wurtzite ZnO. The resistivity has a sharply reduction with the Sb content from 0.228 Ω·m of 3.95% Sb to 4.68 × 10−5 Ω·m of 5.32% Sb. The lowest resistivity is lower at least one order of magnitude than the results of others with the similar Sb content. The Seebeck coefficient indicates that the 5.32% Sb film remains stable p-type conduction. The carrier concentration is about 1020 cm−3 and is higher at least one order of magnitude than the other results. Raman analysis indicates that the peak of E2high related O sublattice vibrations indicates that the O sites are substituted by Sb3+ ions, which increases the carrier concentration. However, the mobility is relatively weak because the intrinsic host lattice defects activated as vibrating complexes. The power factor of the p-type ZnO:Sb of the 5.32% Sb film at 427 °C is 46.79 μW/m·K2.

Graphical abstract

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Effects of ZnO nanoparticles in the Caspian roach (Rutilus rutilus caspicus)

Publication date: 1 June 2018
Source:Science of The Total Environment, Volume 626
Author(s): K. Khosravi-Katuli, G. Lofrano, H. Pak Nezhad, A. Giorgio, M. Guida, F. Aliberti, A. Siciliano, M. Carotenuto, E. Galdiero, E. Rahimi, G. Libralato
Most studies investigating the toxicity of zinc oxide nanoparticles (ZnO NPs) focused on the effect of size, whereas exposure concentration and duration remained poorly understood. In this study, the effect of acute and sub-acute exposures of ZnO NPs on Zn compartmentalization and biomarkers' expression were investigated in Rutilus rutilus caspicus (Caspian roach) considering various exposure scenarios: i) the assessment of the concentration-response curves and median lethal concentration (LC50); ii) the assessment of the effects of organisms exposed at LC50 value and one tenth of LC50 value of ZnO NPs suspensions for 4 d and 28 d, respectively; iii) the assessment of 14 d depuration period. The same concentrations of ZnSO4 were investigated. The highest Zn accumulation was detected in gill after sub-acute exposure (4.8 mg/L; 28 d) followed by liver, kidney and muscle. In gill, liver and muscle, Zn from Zn NPs accumulated higher concentrations. Depuration (14 d) decreased Zn content in each organ, but no complete removal occurred except for muscle. Biomarkers' activity was significantly over expressed after treatments, but depuration brought back their values to background levels and most effects were related to acute concentrations (48 mg/L; 4 d) and in presence of ZnSO4. Histopathological analyses showed that the exposure to ZnO NPs increased lesions in gill, liver and kidney, with a direct proportionality between alterations and Zn accumulated in the target organs. After depuration, lesions regressed for both ZnO NPs and ZnSO4, but not in a complete way. These data could contribute to increase the knowledge about ZnO NPs risk assessment in aquatic vertebrates, suggesting that the size of ZnO NPs can influence biomarker and histopathological effects.

Graphical abstract

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Characterizing heavy metals in combined sewer overflows and its influence on microbial diversity

Publication date: 1 June 2018
Source:Science of The Total Environment, Volume 625
Author(s): Zuxin Xu, Jun Wu, Huaizheng Li, Yanbo Chen, Jin Xu, Lijun Xiong, Jin Zhang
This study characterized the pollution levels and potential ecological risk of heavy metals in combined sewer overflows (CSOs) and their effects on microbial diversity in nearby riparian sediments. The chemical fractionations of Zn, Cd, Cr, and Cu in dry-weather flows, wet-weather flows (CSO discharges), sewer sediments, and surface runoffs were determined. Geo-accumulation (Igeo) and ecological risk (RI) indexes were employed for metal risk assessment. DNA extraction and polymerase chain reaction (PCR) amplification on the Illumina MiSeq platform were conducted. The results show that heavy metals contents in fine-sized fractions have higher values than those in coarse-sized fractions. Chemical fractionation analysis suggests that Zn and Cd are two of the most bioavailable metals impacted by anthropogenic activities. Cr and Cu contents in CSOs are relatively stable and could exist for extended periods. According to the RI analysis, CSOs pose a considerable risk (RI-G2) to receiving waters due to the higher bioavailability of Cd, which was consistent with the Igeo index. Furthermore, under the stress of the highly-bioavailable Cd and Cu, Gram +ves in the riparian benthic sediment gradually became dominant with metal-tolerance property. Therefore, long-term exposure to highly bioavailable metals could exhibit great impacts on microbial diversity.

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Solvent extraction of zinc from synthetic Zn-Cd-Mn chloride solution using D2EHPA: Optimization and thermodynamic studies

Publication date: 31 May 2018
Source:Separation and Purification Technology, Volume 197
Author(s): Hossein Jafari, Hadi Abdollahi, Mahdi Gharabaghi, Ali Asghar Balesini
The extraction of zinc in the presence of manganese and cadmium from chloride solution with di 2 ethyl hexyl phosphoric acid (D2EHPA) in kerosene diluent were comprehensively investigated. The extraction experiments were carried out in order to determine the influential parameters in the conditions of A:O ratio of 1:1, pH range of 1–6, temperatures of 30 °C, 40 °C and 50 °C in an aqueous solution with concentrations of 5 g/L of zinc, manganese and cadmium. The variety of influential parameters in the process such as equilibrium pH, concentration of D2EHPA, temperature, contact time, initial concentration of ions and also thermodynamic parameters of zinc extraction in chloride solution were precisely evaluated. The results showed that in the optimal condition of pH = 2.5–3, temperature 40 °C and [D2EHPA] = 10 v/v, the extraction of Zn, Mn and Cd were 97%, 14% and 3% respectively. ΔpH0.5Zn-Mn and ΔpH0.5Zn-Cd in this condition respectively equal to 2.5 and more than 5.25. Also, the study indicated that the predominant zinc species extracted by D2EHPA was ZnCl+. Based on thermodynamic studies, the values of ΔHo, ΔSo and ΔGo for zinc extraction in condition of temperature 40 °C and [D2EHPA] = 10 v/v are 25.65 kJ.mol−1, 79.20 J·K−1·mol−1 and 0.86 kJ·mol−1 respectively. Furthermore, the results showed that under constant concentration of D2EHPA, changes in the initial concentrations of Zn, Mn and Cd in the chloride solution were most effective in their separation.

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Facile preparation of fluorescent layered double hydroxide polymeric composites through the photo-induced surface-initiated controlled living polymerization

Publication date: 1 May 2018
Source:Applied Surface Science, Volume 439
Author(s): Junyu Chen, Meiying Liu, Qiang Huang, Ruming Jiang, Hongye Huang, Fengjie Deng, Yuanqing Wen, Jianwen Tian, Xiaoyong Zhang, Yen Wei
(Zn/Al) layered double hydroxide (LDH) based fluorescence probes have been facilely fabricated via photo-induced surface-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization, which demonstrated green fluorescence, good biocompatibility and excellent dispersion performance in aqueous solution. The as prepared (Zn/Al)LDH polymeric composites were modified with 2-methacryloyloxyethyl phosphorylcholine (MPC), acrylic acid (AA) and diacroloyl-fluorescein (Ac-Fl). Among them, the comonomers MPC and AA were used to endow their water dispersibility, biocompatibility and potential drug carriers, while the Ac-Fl was served both as the fluorescence signal and photocatalyst for RAFT polymerization. A series of characterization methods, including 1H nuclear magnetic resonance spectroscopy, Fourier transform infrared spectroscopy, transmission electronic microscopy, thermogravimetric analyses, X-ray photoelectron spectroscopy were employed to conform the successful of surface modification of LDH through photo-induced surface-initiated RAFT polymerization. Besides, UV-vis absorption spectra and fluorescence spectra were adopted to evaluate the optical characteristics of as prepared (Zn/Al)LDH-co-Poly(MPC-AA-Fl) composites, which exhibited high intense green fluorescence. Furthermore, the endocytosis behavior indicates that (Zn/Al)LDH-co-Poly(MPC-AA-Fl) composites could be potentially used in cell imaging and even drug delivery application for their excellent biocompatibility and all advantages described above.

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Contamination characteristics and source apportionment of heavy metals in topsoil from an area in Xi’an city, China

Publication date: 30 April 2018
Source:Ecotoxicology and Environmental Safety, Volume 151
Author(s): Xiuduan Chen, Xinwei Lu
As soil-extractable elements potentially pose ecological and health risks, identifying their contamination characteristics and sources is crucial. Therefore, to understand topsoil trace elements in the urban ring zone from the Second Ring Road to the Third Ring of Xi'an city in China, we determined the concentrations of Zn, Co, V, As, Cu, Mn, Ba, Ni and Pb, and analyzed the sources of the contamination. The results showed that the individual pollution indices of Pb, Co, Cu, Zn, Ba, Ni, Mn, As, and V were 1.79, 1.48, 1.41, 1.33, 1.20, 1.07, 1.04, 0.99, and 0.99, respectively. Evaluation with the aid of the pollution load index (PLI) indicated slight soil contamination by these elements in the study area. Using the positive matrix factorization (PMF) method, we identified four sources of contamination, namely (1) a natural source, (2) traffic emission source, (3) industrial emission source, and (4) mixed source. PMF is an effective tool for source apportionment of heavy metals in topsoil. The contribution rates of the natural source, traffic source, mixed source, and industrial source to the heavy metal contamination were specified as 25.04%, 24.71%, 24.99%, and 25.26%, respectively. Considering the above, any attempt to reduce the soil environmental cost of urban development, has to take into account the heavy metal contamination of the topsoil from industries, traffic, and other activities.



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Consensus Recommendations for Treatment Strategies in Indians Using Botulinum Toxin and Hyaluronic Acid Fillers

imageBackground: Indians constitute one of the largest population groups in the world. Facial anthropometry, morphology, and age-related changes in Indians differ from those of other ethnic groups, necessitating a good understanding of their facial structure and the required aesthetic treatment strategies. However, published recommendations specific to Indians are few, particularly regarding combination treatment. Methods: The Indian Facial Aesthetics Expert Group (19 dermatologists, plastic surgeons, and aesthetic physicians with a mean 15.5 years' aesthetic treatment experience) met to develop consensus recommendations for the cosmetic facial use of botulinum toxin and hyaluronic acid fillers, alone and in combination, in Indians. Treatment strategies and dosage recommendations (agreed by ≥ 75% of the group) were based on results of a premeeting survey, peer-reviewed literature, and the experts' clinical experience. Results: The need for combination treatment increases with age. Tear trough deficiency is the most common midface indication in Indian women aged 20–40 years. In older women, malar volume loss and jowls are the most common aesthetic concerns. Excess medial soft tissue on a relatively smaller midface precedes age-related sagging. Hence, in older Indians, fillers should be used peripherally to achieve lift and conservatively in the medial zones to avoid adding bulk medially. The shorter, wider lower face requires 3-dimensional correction, including chin augmentation, to achieve increased facial height and the oval shape desired by most Indian women. Conclusions: These recommendations give physicians treating Indians worldwide a better understanding of their unique facial characteristics and provide treatment strategies to achieve optimal aesthetic outcomes.

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Monobloc Reconstruction of Dome, Medial Crura, and Columella with Gamma-Shaped Costal Cartilage Graft

imageSummary: In severe nasal deformities, the original cartilages are removed, or they become unusable because of previous operations. Costal cartilage (CC) is one of the most important tools for the replacement of deficient nasal osteocartilaginous framework. In 4 secondary and 1 tertiary rhinoplasty cases with severe deformities of medial and lateral crura of the lower lateral cartilages, we have prepared a long strut graft from a CC and then split the graft tip 5–6 mm vertically into 2 equal halves to create a gamma (υ)-shaped strut graft. We have sutured the base of this graft to the nasal spine and/or the bases of the medial crural remnants. Then, we have prepared lateral crural grafts and secured the grafts over lateral crural remnants. Then we curved the split tip winglets of the υ-shaped strut graft to both sides and sutured them to lateral crural grafts in order to create a new dome. Splitting of the CC strut graft reduces the need for extensive suturing at the tip, obtains smoother contours and ensures graft economy, and provides an original and stable dome shape. The bending capacity of the CC is limited in middle-aged patients. Costal allografts from a young cadaver can be a good alternative. υ-shaped costal crural graft is useful for medial crural and domal monobloc reconstruction in secondary and tertiary cases.

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The Superiorly Based Partial Rectus Abdominis and External Oblique Flap: A New Technique for Breast Asymmetry Reconstruction

imageSummary: Breast asymmetry has a wide spectrum of presentations with several employable strategies for surgical correction. Historically, the external oblique muscle has proven to be a versatile flap option for the reconstruction of both local and distant defects. It has also been described for use in breast reconstruction for coverage of the lower pole of implant prostheses. The external oblique muscle flap can be harvested in several ways to capture overlying fat and skin. In this study, we describe the use of a superiorly based partial rectus and external oblique flap for surgical correction of lower pole breast hypoplasia. This flap provides vascularized autologous volume to the lower pole of the breast with minimal donor morbidity. Other advantages of this flap are that it can increase the nipple to inframammary fold distance and lower the inframammary fold. This technique represents an evolution of an under-utilized flap and is the first study describing the use of the external oblique flap in the management of breast asymmetry.

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Combined fMRI- and eye movement-based decoding of bistable plaid motion perception

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Publication date: 1 May 2018
Source:NeuroImage, Volume 171
Author(s): Gregor Wilbertz, Madhura Ketkar, Matthias Guggenmos, Philipp Sterzer
The phenomenon of bistable perception, in which perception alternates spontaneously despite constant sensory stimulation, has been particularly useful in probing the neural bases of conscious perception. The study of such bistability requires access to the observer's perceptual dynamics, which is usually achieved via active report. This report, however, constitutes a confounding factor in the study of conscious perception and can also be biased in the context of certain experimental manipulations. One approach to circumvent these problems is to track perceptual alternations using signals from the eyes or the brain instead of observers' reports. Here we aimed to optimize such decoding of perceptual alternations by combining eye and brain signals. Eye-tracking and functional magnetic resonance imaging (fMRI) was performed in twenty participants while they viewed a bistable visual plaid motion stimulus and reported perceptual alternations. Multivoxel pattern analysis (MVPA) for fMRI was combined with eye-tracking in a Support vector machine to decode participants' perceptual time courses from fMRI and eye-movement signals. While both measures individually already yielded high decoding accuracies (on average 86% and 88% correct, respectively) classification based on the two measures together further improved the accuracy (91% correct). These findings show that leveraging on both fMRI and eye movement data may pave the way for optimized no-report paradigms through improved decodability of bistable motion perception and hence for a better understanding of the neural correlates of consciousness.



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