Abstract
We read with great interest the results of a nationwide cohort study published by Egeberg et al.1 demonstrating that the prevalence of coeliac disease, Crohn disease, ulcerative colitis, irritable bowel syndrome, small intestinal bacterial overgrowth (SIBO) and Helicobacter pylori infection was higher among patients with rosacea when compared with controls. Recently, with regard to the same cohort, the authors indicated that rosacea constitutes an independent risk factor for Parkinson disease (PD).2
The entire gastrointestinal tract (GIT) is affected in PD and motility disorders are included in the most common nonmotor manifestations in these patients. Additionally, increasing evidence suggests that GIT might be the site of initiation of PD. Persistent gastric or intestinal infection with H. pylori and SIBO deteriorates motor fluctuations.
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