Checks and Balances: Rpd3 Issues Executive Orders in Developmental Enhancer Regulation

Publication date: 27 February 2017
Source:Developmental Cell, Volume 40, Issue 4
Author(s): Sara Martire, Laura Banaszynski
Stem cells use poised enhancers of developmental regulators to maintain pluripotency and for subsequent activation in differentiating progeny. In this issue of Developmental Cell, Janssens et al. (2017) demonstrate that the erm enhancer is maintained in a poised state in neural stem cells by the histone deacetylase Hdac1/Rpd3.

Teaser

Stem cells use poised enhancers of developmental regulators to maintain pluripotency and for subsequent activation in differentiating progeny. In this issue of Developmental Cell, Janssens et al. (2017) demonstrate that the erm enhancer is maintained in a poised state in neural stem cells by the histone deacetylase Hdac1/Rpd3.


http://ift.tt/2m8d9dj