The diagnostic value of contrast-enhanced computed tomography imaging for detection of colorectal tumors: A meta-analysis

Qing Yu, Jie Liu

Journal of Cancer Research and Therapeutics 2016 12(8):241-243

Objective: To evaluate the application usage of contrast-enhanced computer tomography imaging for colorectal tumors diagnosis. Methods: By searching the Medline and CNKI databases, we collected all diagnostic tests about contrast-enhanced CT imaging for colorectal tumors. Sensitivity and specificity were calculated to evaluate the usage of individual diagnostic tests. The data were analyzed using statistic software Meta-DiSc 1.4. Results: Nine trials that included a total of 4797 patients were analyzed in this study. The summary diagnosis sensitivity and specificity of contrast-enhanced CT were 0.74 (95% confidence interval [CI]: 0.71–0.77) and 0.86 (0.85–0.87), respectively. The pooled area under the receiver operating characteristic curve was 0.90. Subgroup analysis: for intravenous contrast enhancement technology, the pooled diagnosis sensitivity and specificity were 0.63 (95% CI: 0.56–0.69) and 0.89 (95% CI: 0.86–0.92); for oral contrast enhancement technology, the pooled diagnosis sensitivity and specificity were 0.78 (95% CI: 0.74–0.81) and 0.86 (95% CI: 0.84–0.87). Conclusion: Contrast-enhanced CT imaging can be regarded as an effective and feasible method for detection of the colorectal tumors.

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