Publication date: Available online 27 March 2017
Source:Photodiagnosis and Photodynamic Therapy
Author(s): Reza Fekrazad, Bahman Seraj, Nasim Chiniforush, Mehrak Rokouei, Niloofar Mousavi, Sara Ghadimi
BackgroundAntimicrobial photodynamic therapy (aPDT) is a novel technique for reduction of pathogenic microorganisms in dentistry. The aim of this study was to evaluate the effects of aPDT on Streptococcus mutans reduction in children with severe early childhood caries.MethodsTwenty-two children with severe early childhood caries aged 3 to 6 years were treated with toluoidine blue O (TBO) for 1 minute and irradiated by a Light Emitting Diode (LED; FotoSan, CMS Dental, Denmark) with the exposure time of 150seconds. Saliva samples were collected at baseline, 1hour and 7 days after treatment. Streptococcus mutans counts were determined using the Dentocult SM Strip mutans.ResultsThe counts of Streptococcus mutans in saliva decreased significantly after 1hour (P<0.001). However, the difference in reduction of Streptococcus mutans counts in saliva was not significant between the baseline and 7 days after treatment (P>0.05).ConclusionaPDT seems to be efficient to reduce salivary Streptococcus mutans immediately after treatment in children with severe early childhood caries. However, further researches are needed to evaluate different doses and frequency of irradiation in combination with restoring carious teeth to find more durable results.
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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