Real-time light dosimetry for intra-cavity photodynamic therapy: Application for pleural mesothelioma treatment

Publication date: June 2017
Source:Photodiagnosis and Photodynamic Therapy, Volume 18
Author(s): Nacim Betrouni, Camille Munck, Wael Bensoltana, Grégory Baert, Anne-Sophie Dewalle-Vignion, Arnaud Scherpereel, Serge Mordon
Complete and homogeneous illumination of the target is necessary for the success of a photodynamic therapy (PDT) procedure. In most applications, light dosimetry is done using detectors placed at strategic locations of the target. In this study we propose a novel approach based on the combination of light distribution modeling with spatial localization of the light applicator for real time estimation and display of the applied dose on medical images. The feasibility approach is demonstrated for intrapleural PDT of malignant pleural mesothelioma.



http://ift.tt/2mVuILD