PET-NECK: a multicentre randomised Phase III non-inferiority trial comparing a positron emission tomography–computerised tomography-guided watch-and-wait policy with planned neck dissection in the management of locally advanced (N2/N3) nodal metastases in patients with squamous cell head and neck cancer.

PET–CT-guided active surveillance for locally advanced nodal metastases in head and neck cancer showed similar survival to planned neck dissection, with better quality of life and lower costs.

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