Early stage screening of breast cancer using electrochemical biomarker detection

Publication date: June 2017
Source:TrAC Trends in Analytical Chemistry, Volume 91
Author(s): Mohammad Hasanzadeh, Nasrin Shadjou, Miguel de la Guardia
Recently researchers have driven their attention in the development of biosensors for breast cancer detection using different biomarkers. This review reports a systematic study of the usefulness of marker-based electrochemical biosensors in breast cancer and its early diagnosis. Also, various types of electro-analytical methods for early stage screening of breast cancer were discussed. The emphasis is placed on immune-, geno- cyto- and enzyme-biosensing strategies. In addition, the advantages offered by some nano-materials in detection of breast cancer biomarkers are illustrated with representative recent examples that highlight the scientific interest in widening the use of new materials/methods in electrochemical biosensing methods. We also present a comprehensive overview of current developments and key issues in the determination of some breast cancer biomarkers, with an emphasis on evaluating the methods.



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