Complementary and Alternative Therapies for Restless Leg Syndrome: An Evidence-Based Systematic Review

Restless leg syndrome (RLS) is defined as an irresistible urge to move the legs, which is usually accompanied by paresthesias or dysesthesias, and affects 2% to 4% of adults in Europe and North America at least twice weekly. This systematic review assesses the current complementary and alternative options for RLS and the potential benefits of those treatments on sleep quality, mood disorder, and quality of life. A systematic search of the PubMed, Embase, Cochrane, and Web of Science databases was conducted.

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