Complex liver cysts in Autosomal Dominant Polycystic Kidney Disease

Publication date: Available online 25 July 2017
Source:Clinical Imaging
Author(s): Zerwa Farooq, Ashkan Heshmatzadeh Behzadi, Jon D. Blumenfeld, Yize Zhao, Martin R. Prince
PurposeTo determine prevalence of complex liver cysts in Autosomal Dominant Polycystic Kidney Disease (ADPKD).MethodsAbdominal MRI in 186 ADPKD subjects were evaluated by two independent observers to determine prevalence of complex liver cysts.Results23 (12%) of subjects, had at least 1 complex cyst. Only 8 (4%) were reported to have a complex cyst prospectively, representing an under-reporting rate of 65%. Median total cyst volume was 66-times greater for subjects with complex cysts compared to subjects without (p<0.0001).ConclusionComplex hepatic cysts were observed in 12% of ADPKD cases, occurring more frequently in livers with extensive cystic involvement.



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