Gating Ciliary Transport

Publication date: 10 July 2017
Source:Developmental Cell, Volume 42, Issue 1
Author(s): Irma Sánchez, Brian D. Dynlacht
Cilia lack the ability to synthesize proteins and thus require dynamic transport. Reporting in this issue of Developmental Cell, Kanie et al. (2017) shed light on the mechanism of transport by implicating CEP19, which is associated with an autosomal-recessive obesity syndrome when mutated, in the triggering of intraflagellar transport.

Teaser

Cilia lack the ability to synthesize proteins and thus require dynamic transport. Reporting in this issue of Developmental Cell, Kanie et al. (2017) shed light on the mechanism of transport by implicating CEP19, which is associated with an autosomal-recessive obesity syndrome when mutated, in the triggering of intraflagellar transport.


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