Environments Tune and Select Cellular Diversity

Publication date: Available online 31 July 2017
Source:Trends in Immunology
Author(s): Brian A. Kidd
Technical advances in single-cell sequencing data and their application to greater samples is revealing substantial cell-to-cell variation in expression levels and propagation of this variation between molecules across cells. New quantitative approaches that apply mechanistic and statistical models in a systems-wide approach are illuminating the drivers of phenotypic diversity.



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