Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease

Publication date: 1 August 2017
Source:Cell Metabolism, Volume 26, Issue 2
Author(s): Adil Mardinoglu, Alena Stančáková, Luca A. Lotta, Johanna Kuusisto, Jan Boren, Matthias Blüher, Nicholas J. Wareham, Ele Ferrannini, Per Henrik Groop, Markku Laakso, Claudia Langenberg, Ulf Smith
Plasma mannose levels are elevated in subjects with insulin resistance independently of obesity. Here, we found that elevated plasma mannose levels are strong markers of future risk of several chronic diseases including T2D, CVD, and albuminuria, and that it may contribute to their development rather than just being a novel biomarker.

Teaser

Mardinoglu et al. found that elevated plasma mannose levels are strong markers of future risk of several chronic diseases, including T2D, CVD, and albuminuria, and they may also contribute to their development rather than just being a novel biomarker.


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