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Δευτέρα 6 Νοεμβρίου 2017

Imaging findings in systemic childhood diseases presenting with dermatologic manifestations

Publication date: May–June 2018
Source:Clinical Imaging, Volume 49
Author(s): Adam Z. Fink, Julia K. Gittler, Radhika N. Nakrani, Jonathan Alis, Einat Blumfield, Terry L. Levin
PurposeMany childhood diseases often present with skin abnormalities with which radiologists are largely unfamiliar. Knowledge of associated dermatologic manifestations may aid the radiologist in confirming the diagnosis and recommending targeted imaging of affected organs.MethodsWe review the imaging findings in childhood diseases associated with dermatologic manifestations.FindingsDiseases include dermatologic findings which herald underlying malignancy (Neuroblastoma, leukemia/lymphoma, Langerhans cell histiocytosis),are associated with risk of malignancy (Epidermolysis Bullosa, basal cell nevus syndrome, Cowden's syndrome, Tuberous Sclerosis),or indicate a systemic inflammatory/immune disorder (Kawasaki's disease, Henoch Schonlein Purpura, systemic lupus erythematosus, scleroderma, sarcoidosis, dermatomyositis and immune thrombocytopenic purpura).ConclusionFamiliarity with pertinent findings in childhood diseases presenting with dermatologic manifestations in childhood diseases aids the radiologist in confirming the diagnosis and guiding imaging workup.



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