Efficacy and safety of regorafenib with schedule 2/1 for patients≥ 75 years with metastatic colorectal cancer (mCRC) after failure of two lines of chemotherapy
R Petrioli, M Chirra, L Messuti, AI Fiaschi, V Savelli… - Clinical Colorectal Cancer, 2018
… Treatment was delayed if on the planned treatment day the neutrophil count was < 1,500/mm
3 , the platelet count was < 100,000/mm 3 , or the patient had persistent diarrhea or stomatitis
of grade 1 or higher … Nausea, 3 (13%), 0, 0. Vomiting, 2 (9%), 0, 0. Stomatitis, 1 (4%), 0, 0 …
3 , the platelet count was < 100,000/mm 3 , or the patient had persistent diarrhea or stomatitis
of grade 1 or higher … Nausea, 3 (13%), 0, 0. Vomiting, 2 (9%), 0, 0. Stomatitis, 1 (4%), 0, 0 …
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Novel recombinant exosome and use thereof
H Yeon-Sun, YS Yang, CH Jeong, IS Kim - US Patent App. 15/650,272, 2018
… GLUT14. 3. The recombinant exosome of claim 1 , wherein the membrane fusogenic
protein is vesicular stomatitis virus glycoprotein (VSV-G), tat protein of HIV,
HSV-1 gB, EBV gB, thogoto virus G protein, or AcMNPV gp64. 4 …
protein is vesicular stomatitis virus glycoprotein (VSV-G), tat protein of HIV,
HSV-1 gB, EBV gB, thogoto virus G protein, or AcMNPV gp64. 4 …
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Human oral microbiota and its modulation for oral health
Y Zhang, X Wang, H Li, C Ni, Z Du, F Yan - Biomedicine & Pharmacotherapy, 2018
The oral microbiome is an important part of the human microbiome. The oral cavity contains
several significantly different niches with distinct microbial commun.
several significantly different niches with distinct microbial commun.
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T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells
LK Beura, S Wijeyesinghe, EA Thompson… - Immunity, 2018
… We generated CD45.1 + OT-I (CD8 + TCR transgenic mice specific for ovalbumin-derived
SIINFEKL peptide) immune chimeras through immunization with recombinant ovalbumin-
expressing vesicular stomatitis virus (VSVova) infection iv, which results in OT-I Trm cells within …
SIINFEKL peptide) immune chimeras through immunization with recombinant ovalbumin-
expressing vesicular stomatitis virus (VSVova) infection iv, which results in OT-I Trm cells within …
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[HTML] Orf virus infection in Alaskan mountain goats, Dall's sheep, muskoxen, caribou and Sitka black-tailed deer
M Tryland, KB Beckmen, KA Burek-Huntington… - Acta Veterinaria …, 2018
… Orf virus (ORFV) is the type species of the genus Parapoxvirus of the Poxviridae family, which
also includes Bovine papular stomatitis virus, Pseudocowpox virus and Parapoxvirus of red deer
in New Zealand [1]. ORFV is distributed worldwide with domestic sheep and goats …
also includes Bovine papular stomatitis virus, Pseudocowpox virus and Parapoxvirus of red deer
in New Zealand [1]. ORFV is distributed worldwide with domestic sheep and goats …
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1, 4-Naphthoquinone derivatives potently suppress Candida albicans growth, inhibit formation of hyphae and show no toxicity toward zebrafish embryos
M Janeczko, K Kubiński, A Martyna, A Muzyczka… - Journal of Medical …, 2018
… Nittayananta W, Pangsomboon K, Panichayupakaranant P, Chanowanna N, Chelae S et al. Effects
of lawsone methyl ether mouthwash on oral Candida in HIV-infected subjects and subjects with
denture stomatitis. J Oral Pathol Med 2013;42:698–704 [CrossRef][PubMed]. 16 …
of lawsone methyl ether mouthwash on oral Candida in HIV-infected subjects and subjects with
denture stomatitis. J Oral Pathol Med 2013;42:698–704 [CrossRef][PubMed]. 16 …
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Method for Simple and Rapid Concentration of Zika Virus Particles from Infected Cell-Culture Supernatants
V Richard, M Aubry - Journal of Virological Methods, 2018
… Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration
to very high titer and efficient gene transfer into mammalian and nonmammalian cells.
Proc. Natl. Acad. Sci. USA, 90 (1993), pp. 8033–8037 …
to very high titer and efficient gene transfer into mammalian and nonmammalian cells.
Proc. Natl. Acad. Sci. USA, 90 (1993), pp. 8033–8037 …
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An alanine residue in human parainfluenza virus type 3 phosphoprotein is critical for restricting excessive N 0-P interaction and maintaining N solubility
S Zhang, Q Cheng, C Luo, L Yin, Y Qin, M Chen - Virology, 2018
The phosphoprotein (P) of human parainfluenza virus type 3 (HPIV3) plays a pivotal role
in viral RNA synthesis, which interacts with the nucleoprotein (N) to fo.
in viral RNA synthesis, which interacts with the nucleoprotein (N) to fo.
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[HTML] A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus …
B Callendret, J Vellinga, K Wunderlich, A Rodriguez… - PloS one, 2018
… information. The vesicular stomatitis virus (VSV)- based vectors vaccines are likely
to be approved for use in a ring vaccination setting [8, 9, 19], but there is still a need
for a prophylactic vaccine with broad specificity. Vaccines …
to be approved for use in a ring vaccination setting [8, 9, 19], but there is still a need
for a prophylactic vaccine with broad specificity. Vaccines …
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[HTML] Phase 3 study of ceritinib vs chemotherapy in ALK-rearranged NSCLC patients previously treated with chemotherapy and crizotinib (ASCEND-5): Japanese subset
K Kiura, F Imamura, H Kagamu, S Matsumoto, T Hida… - Japanese Journal of Clinical …, 2018
Page 1. JJCO Japanese Journal of Clinical Oncology Japanese Journal of Clinical Oncology,
2018, 1–10 doi: 10.1093/jjco/hyy016 Original Article Original Article Phase 3 study of ceritinib
vs chemotherapy in ALK-rearranged NSCLC patients previously …
2018, 1–10 doi: 10.1093/jjco/hyy016 Original Article Original Article Phase 3 study of ceritinib
vs chemotherapy in ALK-rearranged NSCLC patients previously …
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