Shaping the Pluripotent Genome: Switches, Borders, and Loops

Publication date: 1 February 2018
Source:Cell Stem Cell, Volume 22, Issue 2
Author(s): Effie Apostolou
Three-dimensional genome organization is largely cell type specific and requires reorganization during cell fate transitions. A recent study in Nature Genetics (Stadhouders et al., 2018) offers important insights into the principles and drivers of such reorganization during reprogramming of somatic cells into pluripotent stem cells.

Teaser

Three-dimensional genome organization is largely cell type specific and requires reorganization during cell fate transitions. A recent study in Nature Genetics (Stadhouders et al., 2018) offers important insights into the principles and drivers of such reorganization during reprogramming of somatic cells into pluripotent stem cells.


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