Association of Statin Use With Overall and Cancer Survival

To the Editor Emilsson et al suggest that earlier studies associating statin use with improved cancer outcomes were biased by inclusion of prevalent users and by immortal person-time. They emulated a randomized trial of statin use among survivors of colorectal, breast, prostate, and bladder cancer using Surveillance, Epidemiology, and End Results–Medicare data. After accounting for these biases, they observed a null association between postdiagnosis statin initiation and both cancer-specific and all-cause mortality.

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