Atherosclerosis Is an Epigenetic Disease

Publication date: Available online 10 May 2018
Source:Trends in Endocrinology & Metabolism
Author(s): Suowen Xu, Jaroslav Pelisek, Zheng Gen Jin
Atherosclerosis is a chronic inflammatory and lipid-depository disease that eventually leads to acute cardiovascular events. Emerging evidence supports that epigenetic processes such as DNA methylation, histone modification, and noncoding RNAs play an important role in plaque progression and vulnerability, highlighting the therapeutic potential of epigenetic drugs in cardiovascular therapeutics.



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