Blockade of Endothelin-1 Receptor Type B Ameliorates Glucose Intolerance and Insulin Resistance in a Mouse Model of Obstructive Sleep Apnea
J Polák, LA Shimoda, NM Punjabi - Frontiers in Endocrinology, 2018
Obstructive sleep apnea (OSA) is associated with insulin resistance (IR) and glucose
intolerance. Elevated endothelin-1 (ET-1) levels have been observed in OSA
patients and in mice exposed to intermittent hypoxia (IH). We examined whether …
intolerance. Elevated endothelin-1 (ET-1) levels have been observed in OSA
patients and in mice exposed to intermittent hypoxia (IH). We examined whether …
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Obstructive Sleep Apnea during REM Sleep is Associated with Early Signs of Atherosclerosis in Women
M Ljunggren, E Lindberg, KA Franklin, P Öhagen… - Sleep, 2018
Study Objectives While obstructive sleep apnea (OSA) is associated with overall
cardiovascular disease and mortality, the association with atherosclerotic
cardiovascular disease is less clear, especially in women. Recently, it has been …
cardiovascular disease and mortality, the association with atherosclerotic
cardiovascular disease is less clear, especially in women. Recently, it has been …
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Characteristics of Obstructive Sleep Apnea across the Spectrum of Glucose Tolerance in Obese Adolescents
TSH Hannon, S Watson, H Jalou, S Chakravorty… - Frontiers in Endocrinology, 2018
Background: It is not known if dysglycemia and sleep-disordered breathing are
linked in adolescents, as in adults. Objective: To evaluate measures of sleep-
disordered breathing across the spectrum of glucose tolerance in obese …
linked in adolescents, as in adults. Objective: To evaluate measures of sleep-
disordered breathing across the spectrum of glucose tolerance in obese …
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Uvulopalatopharyngoplasty with or without Tonsillectomy in the Treatment of Adult Obstructive Sleep Apnea–A Systematic Review
BA Stuck, MJL Ravesloot, T Eschenhagen… - Sleep Medicine, 2018
Background The most commonly performed surgical procedure for obstructive sleep
apnea (OSA) is uvulopalatopharyngoplasty with or without tonsillectomy (UPPP±TE).
However, there is currently no review solely focusing on clinically relevant effects of …
apnea (OSA) is uvulopalatopharyngoplasty with or without tonsillectomy (UPPP±TE).
However, there is currently no review solely focusing on clinically relevant effects of …
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Correlations Between Waist and Neck Circumferences and Obstructive Sleep Apnea Characteristics
C Tom, B Roy, R Vig, DW Kang, RS Aysola, MA Woo… - Sleep and Vigilance, 2018
Purpose The body mass index (BMI), an estimate of body fat, provides a rather
imprecise indication of risk for obstructive sleep apnea (OSA). We examined whether
other measures, including waist and neck circumferences, provide improved …
imprecise indication of risk for obstructive sleep apnea (OSA). We examined whether
other measures, including waist and neck circumferences, provide improved …
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Obstructive sleep apnea and cerebral white matter change: a systematic review and meta-analysis
BL Ho, PT Tseng, CL Lai, MN Wu, MJ Tsai, CF Hsieh… - Journal of Neurology, 2018
Obstructive sleep apnea (OSA) can cause sleep fragmentation and intermittent
hypoxemia, which are linked to oxidative stress. White matter changes (WMCs)
representing cerebrovascular burden and are at risk factor for oxidative ischemic …
hypoxemia, which are linked to oxidative stress. White matter changes (WMCs)
representing cerebrovascular burden and are at risk factor for oxidative ischemic …
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[HTML] Should we treat any sleep apnea in patients with atrial fibrillation?
D Linz, M Arzt, P Sanders, M Böhm - 2018
… sleep apnea (≥ 80% central events) and 36% had coexisting OSA and CSA (>
20% obstructive events and > 20% central events) [6]. Of those with
moderate-to-severe SDB 34% fulfilled the criteria for Cheyne-Stokes …
20% obstructive events and > 20% central events) [6]. Of those with
moderate-to-severe SDB 34% fulfilled the criteria for Cheyne-Stokes …
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[HTML] Correlation between metabolic syndrome and sleep apnea
A Castaneda, E Jauregui-Maldonado, I Ratnani… - World Journal of Diabetes, 2018
… airways in obese patients was found, providing the first documented relation
between obesity, sleep-induced airway obstruction, sleep fragmentation,
and … Neck circumference is a predictor of metabolic syndrome and obstructive …
between obesity, sleep-induced airway obstruction, sleep fragmentation,
and … Neck circumference is a predictor of metabolic syndrome and obstructive …
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Controversies in office based anesthesia: obstructive sleep apnea considerations.
R Gupta, S Pyati - Minerva anestesiologica, 2018
As the number of procedures being performed in the office based anesthesia (OBA)
setting are increasing, so are the number of patients presenting for surgery with
obstructive sleep apnea (OSA). There continues to be controversy regarding whether …
setting are increasing, so are the number of patients presenting for surgery with
obstructive sleep apnea (OSA). There continues to be controversy regarding whether …
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Sleep Disordered Breathing in C57BL/6J mice with Diet Induced Obesity
T Fleury Curado, H Pho, S Berger, C Caballero-Eraso… - Sleep, 2018
… Conclusion Severe diet induced obesity in mice lead to hypoventilation during wakefulness
and sleep, whereas no significant upper airway obstruction was noted … OSA, obstructive
sleep apnea; OHS, obesity hypoventilation syndrome, PaCO2, partial pressure …
and sleep, whereas no significant upper airway obstruction was noted … OSA, obstructive
sleep apnea; OHS, obesity hypoventilation syndrome, PaCO2, partial pressure …
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