Body Composition in Pituitary, Adrenal and Iatrogenic Cushing's Syndrome and Effects of DHEAS Levels

Abstract

Hypercortisolemia is associated with abdominal adiposity. Prior studies have quantified visceral adipose tissue (VAT) versus subcutaneous adipose tissue (SAT) accumulation as assessed by CT and MRI in patients with pituitary Cushing's disease (1-3) but not of other etiologies. Hormone differences in women with Cushing's syndrome due to pituitary versus adrenal and iatrogenic etiologies, including differences in DHEA production, may affect body composition.

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