Scholar : Oncology Reports - Volume:36 Number:4

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TABLE OF CONTENTS October 2016 Volume 36 Issue 4

Current treatments for advanced melanoma and introduction of a promising novel gene therapy for melanoma (Review) Jae‑Rim Heo, Nam‑Hyung Kim, Jaejin Cho, Kyung‑Chul Choi View Abstract ❯

Parathyroid hormone/parathyroid hormone-related peptide regulate osteosarcoma cell functions: Focus on the extracellular matrix (Review) Dragana Nikitovic, Rafaela‑Maria Kavasi, Aikaterini Berdiaki, Dionysios Papachristou, John Tsiaoussis, Demetrios Spandidos, Aristides Tsatsakis, George Tzanakakis View Abstract ❯

RNAi-mediated HOXD3 knockdown inhibits growth in human RKO cells Fangjun Chen, Guoping Sun, Jun Peng View Abstract ❯

Schisandrin B inhibits cell proliferation and induces apoptosis in human cholangiocarcinoma cells Xiaohui Yang, Shuai Wang, Yunchuan Mu, Yixiong Zheng View Abstract ❯

Crosstalk between Beclin-1-dependent autophagy and caspase‑dependent apoptosis induced by tanshinone IIA in human osteosarcoma MG-63 cells Kun Ma, Chuan Zhang, Man-Yu Huang, Yan-Xing Guo, Guo-Qiang Hu View Abstract ❯

PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTEN Jianbo Xiong, Zhengrong Li, Yang Zhang, Daojiang Li, Guoyang Zhang, Xianshi Luo, Zhigang Jie, Yi Liu, Yi Cao, Zhibiao Le, Shengxing Tan, Wenyu Zou, Peitao Gong, Lingyu Qiu, Yuanyuan Li, Huan Wang, Heping Chen View Abstract ❯

PTK7 overexpression in colorectal tumors: Clinicopathological correlation and prognosis relevance Xiuyun Tian, Liang Yan, Donghai Zhang, Xiaoya Guan, Bin Dong, Min Zhao, Chunyi Hao View Abstract ❯

TGF-β1 regulating miR-205/miR-195 expression affects the TGF-β signal pathway by respectively targeting SMAD2/SMAD7 Yingjun Duan, Qianxue Chen View Abstract ❯

Circulating tumour cells as biomarkers for evaluating cryosurgery on unresectable hepatocellular carcinoma Jian Shi, Yuan Li, Shuzhen Liang, Jianying Zeng, Guifeng Liu, Feng Mu, Haibo Li, Jibing Chen, Mao Lin, Shihou Sheng, Huaiyu Zhang, Tongjun Liu, Lizhi Niu View Abstract ❯

Decreased LIPF expression is correlated with DGKA and predicts poor outcome of gastric cancer Yi Kong, Yan Zheng, Yanfei Jia, Ping Li, Yunshan Wang View Abstract ❯

Next generation deep sequencing identified a novel lncRNA n375709 associated with paclitaxel resistance in nasopharyngeal carcinoma Shuling Ren, Guo Li, Chao Liu, Tao Cai, Zongwu Su, Ming Wei, Li She, Yongquan Tian, Yuanzheng Qiu, Xin Zhang, Yong Liu, Yunyun Wang View Abstract ❯

Expression pattern and methylation of estrogen receptor α in breast intraductal proliferative lesions Xiaoyun Mao, Zhen Qiao, Chuifeng Fan, Ayao Guo, Xinmiao Yu, Feng Jin View Abstract ❯

Combination of the histone deacetylase inhibitor depsipeptide and 5-fluorouracil upregulates major histocompatibility complex class II and p21 genes and activates caspase-3/7 in human colon cancer HCT-116 cells Kouji Okada, Shuko Hakata, Jun Terashima, Toshie Gamou, Wataru Habano, Shogo Ozawa View Abstract ❯

Ultrasound-targeted microbubble destruction of calcium channel subunit α 1D siRNA inhibits breast cancer via G protein-coupled receptor 30 Yanlei Ji, Zhen Han, Limei Shao, Yuehuan Zhao View Abstract ❯

Metastasis-associated protein is a predictive biomarker for metastasis and recurrence in gastric cancer Yoshinaga Okugawa, Yasuhiko Mohri, Koji Tanaka, Mikio Kawamura, Susumu Saigusa, Yuji Toiyama, Masaki Ohi, Yasuhiro Inoue, Chikao Miki, Masato Kusunoki View Abstract ❯

High expression of miR-15b predicts poor prognosis for hepatocellular carcinoma after curative hepatectomy Wen-Bin Ji, Xin Liu, Ying Luo, Wen-Zhi Zhang View Abstract ❯

Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, migration effects and accelerates cell cycle progression in multiple myeloma cells via activating the Akt pathway Dong Zheng, Ziang Chen, Jingfu Chen, Xiaomin Zhuang, Jianqiang Feng, Juan Li View Abstract ❯

miR-145 suppresses colorectal cancer cell migration and invasion by targeting an ETS-related gene Shuling Li, Xiaobing Wu, Yuandong Xu, Shangbiao Wu, Zhifa Li, Rong Chen, Nanqi Huang, Ziyuan Zhu, Xuehu Xu View Abstract ❯

RUNX3 plays an important role in As2O3‑induced apoptosis and allows cells to overcome MSC‑mediated drug resistance Guo‑Zheng Pan, Feng‑Xian Zhai, Yin Lu, Zhi‑Gang Fang, Rui‑Fang Fan, Xiang‑Fu Liu, Dong‑Jun Lin View Abstract ❯

Suppression of CEP55 reduces cell viability and induces apoptosis in human lung cancer Ligang Liu, Qi Mei, Jing Zhao, Yuhong Dai, Qiang Fu View Abstract ❯

Cortactin promotes cell migration and invasion through upregulation of the dedicator of cytokinesis 1 expression in human colorectal cancer Xiaoqian Jing, Huo Wu, Xiaopin Ji, Haoxuan Wu, Minmin Shi, Ren Zhao View Abstract ❯

An integrin αvβ3 antagonistic modified peptide inhibits tumor growth through inhibition of the ERK and AKT signaling pathways Lirong Hu, Jingjing Wang, Ying Wang, Hanmei Xu View Abstract ❯

Fucoidan inhibits angiogenesis induced by multiple myeloma cells Fen Liu, Guoping Luo, Qing Xiao, Liping Chen, Xiaohua Luo, Jinglong Lv, Lixue Chen View Abstract ❯

Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-κB pathway in CD133-positive osteosarcoma MG-63 cells Ka Li, Xin Li, Jiguang Tian, Hongliang Wang, Jingbo Pan, Jianmin Li View Abstract ❯

Expression status of cyclase‑associated protein 2 as a prognostic marker for human breast cancer Lihua Xu, Sida Peng, Qunai Huang, Yu Liu, Hua Jiang, Xi Li, Jiani Wang View Abstract ❯

JQ1, a small molecule inhibitor of BRD4, suppresses cell growth and invasion in oral squamous cell carcinoma Limei Wang, Xiuyin Wu, Ping Huang, Zhijun Lv, Yuping Qi, Xiujuan Wei, Pishan Yang, Fenghe Zhang View Abstract ❯

Membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemia Min-Chan Chen, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu, Ming-Derg Lai View Abstract ❯

Oleuropein inhibits the proliferation and invasion of glioma cells via suppression of the AKT signaling pathway Ming Liu, Jian Wang, Bin Huang, Anjing Chen, Xingang Li View Abstract ❯

CCL22 and IL-37 inhibit the proliferation and epithelial-mesenchymal transition process of NSCLC A549 cells Yu-Hua Chen, Bi-Yun Zhou, Xian-Jing Wu, Jun-Fa Xu, Jun‑Ai Zhang, Yong-Hua Chen, Si-Si Liang View Abstract ❯

Acidic extracellular pH promotes prostate cancer bone metastasis by enhancing PC-3 stem cell characteristics, cell invasiveness and VEGF-induced vasculogenesis of BM-EPCs Sheng Huang, Yubo Tang, Xinsheng Peng, Xingdong Cai, Qingde Wa, Dong Ren, Qiji Li, Jiaquan Luo, Liangping Li, Xuenong Zou, Shuai Huang View Abstract ❯

Overexpression of long non-coding RNA MFI2 promotes cell proliferation and suppresses apoptosis in human osteosarcoma Zhixun Yin, Hongmei Ding, Erming He, Jingmhen Chen, Ming Li View Abstract ❯

MicroRNA-181d is a tumor suppressor in human esophageal squamous cell carcinoma inversely regulating Derlin-1 Dejun Li, Mo Shi, Hongsheng Ji, Gang Chen, Hua Jiang, Zhou Wang View Abstract ❯

miR-451 suppresses bladder cancer cell migration and invasion via directly targeting c-Myc Jun Wang, Xiaomei Zhao, Jianhua Shi, Yiwei Pan, Qinghai Chen, Pengfei Leng, Yan Wang View Abstract ❯

Anticancer effect of 20(S)-ginsenoside Rh2 on HepG2 liver carcinoma cells: Activating GSK-3β and degrading β-catenin Qingqiang Shi, Xueping Shi, Gei Zuo, Wei Xiong, Haixing Li, Pei Guo, Fen Wang, Yi Chen, Jing Li, Di‑Long Chen View Abstract ❯

Depletion of SENP1 suppresses the proliferation and invasion of triple-negative breast cancer cells Zhonghua Wang, Jia Jin, Jian Zhang, Leiping Wang, Jun Cao View Abstract ❯

MicroRNA-19b inhibits proliferation of gastric cancer cells by targeting B-cell CLL/lymphoma 3 Huan Wang, Mei Xiong, Yongwu Hu, Yusheng Sun, Qing Ma View Abstract ❯

AKT1 as the PageRank hub gene is associated with melanoma and its functional annotation is highly related to the estrogen signaling pathway that may regulate the growth of melanoma Jingjing Zhao, Xue Zeng, Ping Song, Xiaohong Wu, Hongbo Shi View Abstract ❯

Casticin induces DNA damage and inhibits DNA repair-associated protein expression in B16F10 mouse melanoma cancer cells Yung-Luen Shih, Jason Chou, Ming-Yang Yeh, Hsiao-Min Chou, Hsiu-Chen Chou, Hsu-Feng Lu, Hung-Sheng Shang, Fu-Shin Chueh, Yung-Lin Chu, Shu-Ching Hsueh, Jing-Gung Chung View Abstract ❯

Overexpression of microRNA-497 suppresses cell proliferation and induces apoptosis through targeting paired box 2 in human ovarian cancer Zhong Lin, Junling Zhao, Xindan Wang, Xuehong Zhu, Liansheng Gong View Abstract ❯

Epigenetically deregulated miR-200c is involved in a negative feedback loop with DNMT3a in gastric cancer cells Yingfei Li, Yuqiang Nie, Sanfang Tu, Hong Wang, Yongjian Zhou, Yanlei Du, Jie Cao, Min Ye View Abstract ❯

Clinical significance of α‑ and β‑Klotho in urothelial carcinoma of the bladder Shunta Hori, Makito Miyake, Sayuri Onishi, Yoshihiro Tatsumi, Yosuke Morizawa, Yasushi Nakai, Satoshi Anai, Nobumichi Tanaka, Kiyohide Fujimoto View Abstract ❯

An efficient and simple co-culture method for isolating primary human hepatic cells: Potential application for tumor microenvironment research Wei Dong, Aiguo Lu, Jingkun Zhao, Shuai Yin, Baochi Ou, Hao Feng View Abstract ❯

MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells Liang Chen, Fang Zhang, Xiu-Gui Sheng, Shi-Qian Zhang, Yue-Ting Chen, Bo-Wen Liu View Abstract ❯

Genome-wide profiling of chemoradiation‑induced changes in alternative splicing in colon cancer cells Wei Xiong, Depei Gao, Yunfeng Li, Xin Liu, Peiling Dai, Jiyong Qin, Guanshun Wang, Kangming Li, Han Bai, Wenhui Li View Abstract ❯

Knockdown of FOXK1 alone or in combination with apoptosis-inducing 5-FU inhibits cell growth in colorectal cancer Yao Wu, Ruyi Xie, Xuehua Liu, Jing Wang, Ying Peng, Weimei Tang, Meiyan Wu, Pei Zhang, Yang Ba, Jinjun Zhao, Aimin Li, Qingzhen Nan, Ye Chen, Side Liu, Jide Wang View Abstract ❯

Nitidine chloride inhibits the malignant behavior of human glioblastoma cells by targeting the PI3K/AKT/mTOR signaling pathway Ming Liu, Jiwei Wang, Qichao Qi, Bin Huang, Anjing Chen, Xingang Li, Jian Wang View Abstract ❯

miR-15a induces cell apoptosis by targeting BCL2L2 and BCL2 in HPV-positive hypopharyngeal squamous cell carcinoma Wuhao Lu, Long Feng, Yan Zhang, Yunyun Ma, Ping Li, Yuanyuan Wang, Yuwen Du, Xiaonan Chen, Shujun Wu, Guoqiang Zhao, Weihua Lou View Abstract ❯

miR-17 inhibits ovarian cancer cell peritoneal metastasis by targeting ITGA5 and ITGB1 Cheng Gong, Zongyuan Yang, Fenghua Wu, Lintao Han, Yi Liu, Wei Gong View Abstract ❯

Clinical effects of miR-101 on prognosis of hepatocellular carcinoma and carcinogenic mechanism of anti-miR-101 Xuecheng Lv, Jinghua Li, Bingnan Yang View Abstract ❯

Increased NEK2 in hepatocellular carcinoma promotes cancer progression and drug resistance by promoting PP1/Akt and Wnt activation Sailan Wen, Yuwu Liu, Manyi Yang, Keda Yang, Jianghai Huang, Deyun Feng View Abstract ❯

Combination of nadroparin with radiotherapy results in powerful synergistic antitumor effects in lung adenocarcinoma A549 cells Xibing Zhuang, Tiankui Qiao, Guoxiong Xu, Sujuan Yuan, Qi Zhang, Xue Chen View Abstract ❯

Curcumin causes DNA damage and affects associated protein expression in HeLa human cervical cancer cells Hung-Sheng Shang, Chuan-Hsun Chang, Yu-Ru Chou, Ming-Yang Yeh, Man-Kuan Au, Hsu-Feng Lu, Yung-Lin Chu, Hsiao-Min Chou, Hsiu-Chen Chou, Yung-Luen Shih, Jing-Gung Chung View Abstract ❯

RLIP76 increases apoptosis through Akt/mTOR signaling pathway in gastric cancer Wenwen Wang, Juan Liu, Jianni Qi, Junyong Zhang, Qiang Zhu, Chengyong Qin View Abstract ❯

Methylation of the SEPT9_v2 promoter as a novel marker for the detection of circulating tumor DNA in breast cancer patients Saki Matsui, Naofumi Kagara, Chieko Mishima, Yasuto Naoi, Masafumi Shimoda, Atsushi Shimomura, Kenzo Shimazu, Seung Kim, Shinzaburo Noguchi View Abstract ❯

The diagnostic value and functional roles of phosphoglycerate mutase 1 in glioma Zhenkuan Xu, Jie Gong, Chuanwei Wang, Yunyan Wang, Yan Song, Wenzhe Xu, Zhiguo Liu, Yuguang Liu View Abstract ❯

Curcumin inhibits H2O2-induced invasion and migration of human pancreatic cancer via suppression of the ERK/NF-κB pathway Lei Cao, Jiangbo Liu, Lun Zhang, Xue Xiao, Wei Li View Abstract ❯

Identification of CD200+ colorectal cancer stem cells and their gene expression profile Shan-Shan Zhang, Zai-Wei Huang, Li-Xuan Li, Jin-Jin Fu, Bing Xiao View Abstract ❯

Thymoquinone induces apoptosis through downregulation of c-FLIP and Bcl-2 in renal carcinoma Caki cells Eun Park, Anil Chauhan, Kyoung-Jin Min, Dong Park, Taeg Kwon View Abstract ❯

Non-thermal gas plasma-induced endoplasmic reticulum stress mediates apoptosis in human colon cancer cells Madduma Ruwan Kumara, Mei Piao, Kyoung Kang, Yea Ryu, Jeong Park, Kristina Shilnikova, Jin Jo, Young Mok, Jennifer Shin, Yeonsoo Park, Seong Kim, Suk Yoo, Jin Hyun View Abstract ❯

Overexpression of CXCR7 induces angiogenic capacity of human hepatocellular carcinoma cells via the AKT signaling pathway Yuhui Chen, Fei Teng, Geying Wang, Zhiyu Nie View Abstract ❯

Foxp3 downregulation in NSCLC mediates epithelial-mesenchymal transition via NF-κB signaling Xi Wang, Ying Liu, Lingling Dai, Qi Liu, Liuqun Jia, Huan Wang, Lin An, Xiaogang Jing, Meng Liu, Pengfei Li, Zhe Cheng View Abstract ❯

Use of rhenium-188 for in vivo imaging and treatment of human cervical cancer cells transfected with lentivirus expressing sodium iodide symporter Min Zhang, Shuo Shi, Rui Guo, Yin Miao, Biao Li View Abstract ❯

Effects of an extract of Celtis aetnensis (Tornab.) Strobl twigs on human colon cancer cell cultures Rosaria Acquaviva, Valeria Sorrenti, Rosa Santangelo, Venera Cardile, Barbara Tomasello, Giuseppe Malfa, Luca Vanella, Andrea Amodeo, Carlo Genovese, Silvana Mastrojeni, Michela Pugliese, Monica Ragusa, Claudia Di Giacomo View Abstract ❯

HBx-induced miR-21 suppresses cell apoptosis in hepatocellular carcinoma by targeting interleukin-12 Dian Yin, Yilang Wang, Wenli Sai, Liang Zhang, Yajun Miao, Lili Cao, Xiaolu Zhai, Xiu Feng, Li Yang View Abstract ❯

MicroRNA-892b influences proliferation, migration and invasion of bladder cancer cells by mediating the p19ARF/cyclin D1/CDK6 and Sp-1/MMP-9 pathways Seung-Shick Shin, Sung-Soo Park, Byungdoo Hwang, Bokyung Moon, Won Kim, Wun-Jae Kim, Sung-Kwon Moon View Abstract ❯

MicroRNA-124 inhibits proliferation, invasion, migration and epithelial-mesenchymal transition of cervical carcinoma cells by targeting astrocyte-elevated gene-1 Xia Zhang, Dajun Cai, Lihua Meng, Bing Wang View Abstract ❯

MicroRNA-140 represses glioma growth and metastasis by directly targeting ADAM9 Xiaogang Liu, Shanjun Wang, Aiqin Yuan, Xunhui Yuan, Bing Liu View Abstract ❯

Overexpression of TRIB3 promotes angiogenesis in human gastric cancer Shaoting Dong, Jianling Xia, Hongqiang Wang, Li Sun, Zhenzhen Wu, Jianping Bin, Yulin Liao, Nailin Li, Wangjun Liao View Abstract ❯

Inhibition of FOXQ1 induces apoptosis and suppresses proliferation in prostate cancer cells by controlling BCL11A/MDM2 expression Xiang Zhang, Lijuan Wang, Yingmei Wang, Shenjia Shi, Huayu Zhu, Fengjin Xiao, Jing Yang, Angang Yang, Xiaoke Hao View Abstract ❯

Identification of brefelamide as a novel inhibitor of osteopontin that suppresses invasion of A549 lung cancer cells Jing Zhang, Osamu Yamada, Shinya Kida, Yoshihisa Matsushita, Shinya Murase, Toshio Hattori, Yuzuru Kubohara, Haruhisa Kikuchi, Yoshiteru Oshima View Abstract ❯

Epigenetic modulation of AR gene expression in prostate cancer DU145 cells with the combination of sodium butyrate and 5'-Aza-2'-deoxycytidine Barbora Fialova, Petra Luzna, Jan Gursky, Katerina Langova, Zdenek Kolar, Katerina Trtkova View Abstract ❯

miR‑1246 and miR‑4644 in salivary exosome as potential biomarkers for pancreatobiliary tract cancer Tatsuya Machida, Takaaki Tomofuji, Takayuki Maruyama, Toshiki Yoneda, Daisuke Ekuni, Tetsuji Azuma, Hisataka Miyai, Hirofumi Mizuno, Hironari Kato, Koichiro Tsutsumi, Daisuke Uchida, Akinobu Takaki, Hiroyuki Okada, Manabu Morita View Abstract ❯

Regulation of DEK expression by AP-2α and methylation level of DEK promoter in hepatocellular carcinoma Ming-Xu Qiao, Chun Li, Ai-Qun Zhang, Ling-Ling Hou, Juan Yang, Hong-Gang Hu View Abstract ❯

Upregulation of microRNA-34a enhances the DDP sensitivity of gastric cancer cells by modulating proliferation and apoptosis via targeting MET Zhandong Zhang, Ye Kong, Wei Yang, Fei Ma, Yonglei Zhang, Sheqing Ji, Er-Min Ma, Hongxing Liu, Yongshun Chen, Yawei Hua View Abstract ❯

miR-124 inhibits proliferation and invasion of human retinoblastoma cells by targeting STAT3 Shu Liu, Chunmei Hu, Yingxue Wang, Guang Shi, Yarong Li, Huang Wu View Abstract ❯

PIN1 in hepatocellular carcinoma is associated with TP53 gene status Jun Bae, Sang Noh, Kyoung Kim, Kyu Jang, Ho Park, Myoung Chung, Byung-Hyun Park, Woo Moon View Abstract ❯

miR-194 is a negative regulator of GEF-H1 pathway in melanoma Bingyu Guo, Qiang Hui, Yu Zhang, Peng Chang, Kai Tao View Abstract ❯

MicroRNA-106a suppresses proliferation, migration, and invasion of bladder cancer cells by modulating MAPK signaling, cell cycle regulators, and Ets-1-mediated MMP-2 expression Seung-Shick Shin, Sung-Soo Park, Byungdoo Hwang, Won Kim, Yung Choi, Wun-Jae Kim, Sung-Kwon Moon View Abstract ❯

6-8 October, 2016, Metropolitan Hotel, Athens, Greece 21st World Congress on Advances in Oncology & 19th International Symposium on Molecular Medicine

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