Comparison of low-dose coronary artery calcium scoring using low tube current technique and hybrid iterative reconstruction vs. filtered back projection

Publication date: Available online 2 February 2017
Source:Clinical Imaging
Author(s): Nada Sulaiman, Jeanette Soon, Jong kwan Park, Christopher Naoum, Shaw-Hua Kueh, Philipp Blanke, Darra Murphy, Jennifer Ellis, Cameron Hague, Jonathon Leipsic
IntroductionWe sought to validate whether low dose CACS CT with hybrid IR (HIR) could replace standard dose filtered back projection (FBP).MethodWe enrolled 100 patients to undergo low dose CACS CT with HIR, in addition to routine full dose FBP.ResultsNo significant difference between full and low dose CT in Agatston score 138.2±360.6 vs. 137.3±356.4 (p=0.272) or calcium mass score 19±48.3 vs. 18.7±49 (p=0.8), respectively. Bland–Altman analysis showed no systematic bias. Calcium volume difference was statistically significant 57.2±134 vs. 55.1±130.2 (p=0.001).ConclusionLow dose CT for calcium scoring with HIR enables stable CACS Agatston score and calcium mass quantification as compared to full dose FBP.

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