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Τετάρτη 20 Σεπτεμβρίου 2017

Scholar : Molecular Medicine Reports - Volume:16 Number:4

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Molecular<br/>Medicine<br/>Reports

TABLE OF CONTENTS

October-2017
Volume 16
Issue 4

View Issue

Molecular mechanisms and potential prognostic effects of REST and REST4 in glioma (Review)

Cuilin Li, Zhifei Wang, Xinyue Tang, Liu Zeng, Xitang Fan, Zhi Li

View Abstract ❯

The role of T helper 17 cells in the pathogenesis of hepatitis B virus-related liver cirrhosis (Review)

Suxia Bao, Jianming Zheng, Guangfeng Shi

View Abstract ❯

Altered profile of mRNA expression in atrioventricular node of streptozotocin‑induced diabetic rats

Frank Christopher Howarth, Khatija Parekh, Petrilla Jayaprakash, Edward Samuel Inbaraj, Murat Oz, Halina Dobrzynski, Thomas Edward Adrian

View Abstract ❯

miR‑4262 inhibits colon cancer cell proliferation via targeting of GALNT4

Jian‑Jun Qu, Xiang‑Yang Qu, De‑Zhen Zhou

View Abstract ❯

Investigation of the molecular mechanisms underlying myotonic dystrophy types 1 and 2 cataracts using microRNA‑target gene networks

Dewang Shao, Xiaoquan Zhu, Wei Sun, Lu Huo, Wei Chen, Hua Wang, Bing Liu, Peng Pan

View Abstract ❯

lncRNA expression character associated with ischemic reperfusion injury

Xiaowei Wu, Hongyi Zhu, Suhua Zhu, Maojuan Hao, Qingping Li

View Abstract ❯

Bcl‑2 associated athanogene 4 promotes proliferation, migration and invasion of gastric cancer cells

Lizhi Yi, Zhenbing Lv, Jianmei Wang, Xianfei Zhong

View Abstract ❯

Upregulation of long non-coding RNA DQ786243 promotes the progression of gastric cancer

Ting Shan, Juanyun Fan, Qin Zhao, Kaiyuan Deng, Jiazeng Xia

View Abstract ❯

Identification of key genes and pathways in Parkinson's disease through integrated analysis

Jingru Wang, Yining Liu, Tuanzhi Chen

View Abstract ❯

Integrated analysis of genome‑wide gene expression and DNA methylation microarray of diffuse large B‑cell lymphoma with TET mutations

Pengfei Liu, Wenhua Jiang, Jinkun Zhao, Huilai Zhang

View Abstract ❯

Co‑expression of Axin and APC gene fragments inhibits colorectal cancer cell growth via regulation of the Wnt signaling pathway

Meili Xu, Xianling Liu, Yan Xu, Shicong Zhu, Yawen Gao

View Abstract ❯

Gene therapy for human ovarian cancer cells using efficient expression of Fas gene combined with γδT cells

Jiajing Lin, Dingyuan Zeng, Hongying He, Guangping Tan, Ying Lan, Fuyan Jiang, Shuting Sheng

View Abstract ❯

Characterization and predicted role of microRNA expression profiles associated with early childhood obesity

Shengrong Ouyang, Renqiao Tang, Zhuo Liu, Feifei Ma, Yuanyuan Li, Jianxin Wu

View Abstract ❯

Atorvastatin protects cardiomyocytes against OGD/R‑induced apoptosis by inhibiting miR‑199a‑5p

Yong Li, Ting Jiang, Xingli Fu, Hao Xu, Jianguo Ji

View Abstract ❯

1,25(OH)2D3 treatment attenuates high glucose‑induced peritoneal epithelial to mesenchymal transition in mice

Lina Yang, Yi Fan, Xiuli Zhang, Wenyu Huang, Jianfei Ma

View Abstract ❯

MicroRNA‑329 serves a tumor suppressive role in colorectal cancer by directly targeting transforming growth factor beta‑1

Baohuan Li, Miaomiao Huang, Meiying Liu, Shiling Wen, Fang Sun

View Abstract ❯

Protein kinase C isozyme expression in right ventricular hypertrophy induced by pulmonary hypertension in chronically hypoxic rats

Chao Zeng, Bin Liang, Rui Jiang, Yiwei Shi, Yongcheng Du

View Abstract ❯

Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate‑induced osteoarthritis rats

Jin‑Woo Jeong, Hye Hyeon Lee, Jongsik Kim, Eun‑Ok Choi, Hyun Hwang‑Bo, Hong Jae Kim, Min Young Kim, Kyu Im Ahn, Gi‑Young Kim, Ki Won Lee, Ki Young Kim, Sung Goo Kim, Su Hyun Hong, Cheol Park, Hee‑Jae Cha, Yung Hyun Choi

View Abstract ❯

Expression profile of C19MC microRNAs in placental tissue of patients with preterm prelabor rupture of membranes and spontaneous preterm birth

Ilona Hromadnikova, Katerina Kotlabova, Katarina Ivankova, Ladislav Krofta

View Abstract ❯

The Toll-like receptor 4 antagonist TAK-242 protects against chronic pancreatitis in rats

Long‑Fei Pan, Lei Yu, Li‑Ming Wang, Jun‑Tao He, Jiang‑Li Sun, Xiao‑Bo Wang, Zheng‑Hai Bai, Hai Wang, Ting‑Lin Yan, Hong‑Hong Pei

View Abstract ❯

Inhibition of ARC promoting the apoptosis of rat pulmonary arterial smooth muscle cells after serum deprivation in vitro

Jie Zhang, Zeyu Wu, Ming Guan, Hongyan Lu, Xuming Mo

View Abstract ❯

Comparison of the neuronal differentiation abilities of bone marrow‑derived and adipose tissue‑derived mesenchymal stem cells

Yani Zheng, Chao Huang, Fang Liu, Haiyan Lin, Xiangqun Yang, Zhiying Zhang

View Abstract ❯

IL‑33 restricts invasion and adhesion of trophoblast cell line JEG3 by downregulation of integrin α4β1 and CD62L

Xiao‑Hui Wang, Wei Liu, Deng‑Xuan Fan, Wen‑Ting Hu, Ming‑Qing Li, Xiao‑Yong Zhu, Li‑Ping Jin

View Abstract ❯

Ganoderic acid A inhibits proliferation and invasion, and promotes apoptosis in human hepatocellular carcinoma cells

Xu Wang, Di Sun, Jiandong Tai, Lei Wang

View Abstract ❯

Effects of Shu Gan Jian Pi formula on rats with carbon tetrachloride‑induced liver fibrosis using serum metabonomics based on gas chromatography‑time of flight mass spectrometry

Hui Jiang, Xiu‑Juan Qin, Wei‑Ping Li, Rong Ma, Ting Wang, Zhu‑Qing Li

View Abstract ❯

In vitro reconstitution of interactions in the CARD9 signalosome

Jin Hee Park, Jae Young Choi, Mir Faisal Mustafa, Hyun Ho Park

View Abstract ❯

Precise epitope determination of the anti-vimentin monoclonal antibody V9

Lucia Tomiyama, Hiroki Kamino, Hiroki Fukamachi, Takeshi Urano

View Abstract ❯

Hyperbaric oxygen alleviates the activation of NLRP‑3‑inflammasomes in traumatic brain injury

Huihui Qian, Qinghe Li, Woda Shi

View Abstract ❯

Identification of pivotal genes and pathways for spinal cord injury via bioinformatics analysis

Zonghao Zhu, Qiang Shen, Liang Zhu, Xiaokang Wei

View Abstract ❯

Analysis of microbial community composition and diversity in postoperative intracranial infection using high‑throughput sequencing

Lixin Ruan, Daowu Wu, Xinchong Li, Qichuan Huang, Laipeng Lin, Jie Lin, Lie Chen, Peisong Xu, Jie Jin, Ningmin Yang, Xianfeng Li

View Abstract ❯

Marine collagen peptides reduce endothelial cell injury in diabetic rats by inhibiting apoptosis and the expression of coupling factor 6 and microparticles

Cuifeng Zhu, Wei Zhang, Jianguo Liu, Bo Mu, Fan Zhang, Nannan Lai, Jianxin Zhou, Aimin Xu, Yong Li

View Abstract ❯

Beclin 1 overexpression inhibits chondrocyte apoptosis and downregulates extracellular matrix metabolism in osteoarthritis

Bin Song, Hong Song, Weiguo Wang, Hongru Wang, Hanyuan Peng, Jing Cui, Rong Wang, Hua Huang, Wei Wang, Lili Wang

View Abstract ❯

Aliskiren has chondroprotective efficacy in a rat model of osteoarthritis through suppression of the local renin-angiotensin system

Kaizhong Yan, Yixin Shen

View Abstract ❯

Anti-CD20 monoclonal antibody combined with adenovirus vector-mediated IL-10 regulates spleen CD4+/CD8+ T cells and T-bet/GATA-3 expression in NOD mice

Aiping Tang, Cheng Li, Zhihong Chen, Tang Li

View Abstract ❯

Associations of adiponectin receptor 2 (AdipoR2) gene polymorphisms and AdipoR2 protein expression levels with the risk of colorectal cancer: A case-control study

Lei Zhou, Hai‑Feng Zhang, Wu Ning, Xin Song, Xin Liu, Ji‑Xi Liu

View Abstract ❯

Osteoclast regulation of osteoblasts via RANK‑RANKL reverse signal transduction in vitro

Shiqian Zhang, Xiaoyu Wang, Guojun Li, Yang Chong, Jie Zhang, Xinzhen Guo, Baoxin Li, Zhenggang Bi

View Abstract ❯

Bombyx mori hemocyte extract has anti-inflammatory effects on human phorbol myristate acetate-differentiated THP‑1 cells via TLR4-mediated suppression of the NF-κB signaling pathway

Young Il Kim, Kwang Ho Choi, Seong Ryul Kim, Tae‑Won Goo, Seung‑Won Park

View Abstract ❯

Electric field exposure promotes epithelial‑mesenchymal transition in human lens epithelial cells via integrin β1‑FAK signaling

Jun Liu, Xiao‑Long Yan, Xiao‑Liang Zheng, Lin Mei, Song Wang, Jing Han, Hong Yan

View Abstract ❯

Production of bFGF monoclonal antibody and its inhibition of metastasis in Lewis lung carcinoma

Yanqing Yang, Zhenming Luo, Yiyang Qin, Yu Zhou, Longcai Gong, Jianfang Huang, Hong Wang

View Abstract ❯

Downregulation of SMP30 in senescent human lens epithelial cells

Shuning Li, Xi Chen, Weixia Lai, Meixia Hu, Xin Zhong, Shaojian Tan, Hao Liang

View Abstract ❯

Rapamycin inhibits spermatogenesis by changing the autophagy status through suppressing mechanistic target of rapamycin-p70S6 kinase in male rats

Shangjing Liu, Longxian Huang, Yanqing Geng, Junlin He, Xuemei Chen, Hao Xu, Rong Li, Yingxiong Wang, Yubin Ding, Xueqing Liu

View Abstract ❯

Screening of the prognostic targets for breast cancer based co-expression modules analysis

Huijuan Liu, Hui Ye

View Abstract ❯

The anti-inflammatory effects of Yunnan Baiyao are involved in regulation of the phospholipase A2/arachidonic acid metabolites pathways in acute inflammation rat model

Xiaobin Ren, Mingzhu Zhang, Lingxiang Chen, Wanli Zhang, Yu Huang, Huazhen Luo, Ling Li, Hongbing He

View Abstract ❯

EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitro

Wei Shen, Shanbang Zhu, Haifeng Qin, Ming Zhong, Jinhui Wu, Rui Zhang, Hongyuan Song

View Abstract ❯

Suppression of hepatic dysfunction in tenascin‑X‑deficient mice fed a high‑fat diet

Shinsaku Yamaguchi, Kohei Kawakami, Kazumi Satoh, Naoki Fukunaga, Kazuhito Akama, Ken‑Ichi Matsumoto

View Abstract ❯

MRI reveals slow clearance of dead cell transplants in mouse forelimb muscles

Yanhui Zhang, Hongyan Zhang, Lijun Ding, Hailu Zhang, Pengli Zhang, Haizhen Jiang, Bo Tan, Zongwu Deng

View Abstract ❯

STRA6 as a possible candidate gene for pathogenesis of osteoporosis from RNA‑seq analysis of human mesenchymal stem cells

Insun Song, Yong Jun Choi, Yilan Jin, Jung‑Woo Kim, Jeong‑Tae Koh, Hyung Min Ji, Seon‑Yong Jeong, Ye‑Yeon Won, Won Kim, Yoon‑Sok Chung

View Abstract ❯

Platelet-rich plasma exhibits beneficial effects for rheumatoid arthritis mice by suppressing inflammatory factors

Shichao Tong, Changqing Zhang, Ji Liu

View Abstract ❯

c-Myc promotes tumor proliferation and anti‑apoptosis by repressing p21 in rhabdomyosarcomas

Jinghang Zhang, Na Song, Dan Zang, Jian Yu, Jinsong Li, Wenyu Di, Ruina Guo, Weixing Zhao, Haijun Wang

View Abstract ❯

Adipose‑derived stem cells and hyaluronic acid based gel compatibility, studied in vitro

Jiayan Guo, Shu Guo, Yuxin Wang, Yanqiu Yu

View Abstract ❯

Homeobox‑containing protein 1 loss is associated with clinicopathological performance in glioma

Ping Zhang, Qinglin Liu, Shaofeng Yan, Guang Yuan, Jie Shen, Gang Li

View Abstract ❯

Long non‑coding RNA AK001796 contributes to cisplatin resistance of non‑small cell lung cancer

Bin Liu, Chun‑Feng Pan, Teng Ma, Jun Wang, Guo‑Liang Yao, Ke Wei , Yi‑Jiang Chen

View Abstract ❯

IL-12 induces autophagy in human breast cancer cells through AMPK and the PI3K/Akt pathway

Yan Lin, Wenbin Kuang, Bitao Wu, Changli Xie, Cuiyin Liu, Zhiguang Tu

View Abstract ❯

miR-127 contributes to ventilator-induced lung injury

Qian Li, Ya‑Li Ge, Min Li, Xiang‑Zhi Fang, Yan‑Ping Yuan, Lei Liang, Shao‑Qiang Huang

View Abstract ❯

FGF18 inhibits MC3T3‑E1 cell osteogenic differentiation via the ERK signaling pathway

Feng Zhai, Na Song, Jisheng Ma, Weiyue Gong, Haishan Tian, Xiaokun Li, Chao Jiang, Haijun Wang

View Abstract ❯

MicroRNA‑494 inhibits nerve growth factor‑induced cell proliferation by targeting cyclin D1 in human corneal epithelial cells

Dan Wu, Tingting Qian, Jiaxu Hong, Gang Li, Weiyun Shi, Jianjiang Xu

View Abstract ❯

miR‑132 in atrial fibrillation directly targets connective tissue growth factor

Gang Qiao, Dongsheng Xia, Zhaoyun Cheng, Guobao Zhang

View Abstract ❯

Pidotimod exacerbates allergic pulmonary infection in an OVA mouse model of asthma

Luo‑Qin Fu, Ya‑Li Li, Ai‑Kun Fu, Yan‑Ping Wu, Yuan‑Yuan Wang, Sheng‑Lan Hu, Wei‑Fen Li

View Abstract ❯

LCMR1 interacts with DEK to suppress apoptosis in lung cancer cells

Yang Xu, Zhixin Liang, Chunsun Li, Zhen Yang, Liangan Chen

View Abstract ❯

Effects of microRNA-26b on proliferation and invasion of glioma cells and related mechanisms

Yun‑Ping Li, Wei‑Min Dai, Qiang Huang, Yuan‑Qing Jie, Guo‑Feng Yu, Xiao‑Feng Fan, An Wu, Dan‑Dan Mao

View Abstract ❯

Human cytomegalovirus miR-US4-5p promotes apoptosis via downregulation of p21-activated kinase 2 in cultured cells

Yaozhong Shao, Ying Qi, Yujing Huang, Zhongyang Liu, Yanping Ma, Xin Guo, Shujuan Jiang, Zhengrong Sun, Qiang Ruan

View Abstract ❯

Identification of miRNA-mRNA crosstalk in laryngeal squamous cell carcinoma

Yonghua Fei, Ping Guo, Fuling Wang, Hu Li, Yanhua Lei, Wei Li, Xuehong Xun, Fengxiang Lu

View Abstract ❯

RAGE antagonism by FPS‑ZM1 attenuates postoperative cognitive dysfunction through inhibition of neuroinflammation in mice

Haibin Zhou, Ting Luo, Changwei Wei, Wenzhen Shen, Ruilin Li, Anshi Wu

View Abstract ❯

Oligomeric proanthocyanidins inhibit apoptosis of chondrocytes induced by interleukin-1β

Meng‑Hong Yin, Yi‑Teng Wang, Qing Li, Guo‑Feng Lv

View Abstract ❯

Fine particulate matter aggravates allergic airway inflammation through thymic stromal lymphopoietin activation in mice

Yan Liu, Gan‑Zhu Feng, Qiang Du, Xiao‑Xiang Jin, Xing‑Ran Du

View Abstract ❯

Effects of reduced β2 glycoprotein I on high glucose‑induced cell death in HUVECs

Jing‑Yun Zhang, Jun Ma, Pei Yu, Guang‑Jie Tang, Chun‑Jun Li, De‑Min Yu, Qiu‑Mei Zhang

View Abstract ❯

Endothelial semaphorin 7A promotes seawater aspiration-induced acute lung injury through plexin C1 and β1 integrin

Minlong Zhang, Xue Yan, Wei Liu, Ruilin Sun, Yonghong Xie, Faguang Jin

View Abstract ❯

Isolation and purification of novel peptides derived from Sepia ink: Effects on apoptosis of prostate cancer cell PC‑3

Fangfang Huang, Yinwen Jing, Guofang Ding, Zuisu Yang

View Abstract ❯

Hispidin rescues palmitate‑induced insulin resistance in C2C12 myotubes

Jong Seok Lee, Jun Myoung Park, Sarah Lee, Hye Jin Lee, Hee‑Sun Yang, Joohong Yeo, Ki Rim Lee, Byung Hyun Choi, Eock Kee Hong

View Abstract ❯

Lutein protects against severe traumatic brain injury through anti‑inflammation and antioxidative effects via ICAM‑1/Nrf‑2

Dianhui Tan, Xiaoping Yu, Moran Chen, Junchen Chen, Jincheng Xu

View Abstract ❯

A homozygous MYO7A mutation associated to Usher syndrome and unilateral auditory neuropathy spectrum disorder

Hong Xia, Pengzhi Hu, Lamei Yuan, Wei Xiong, Hongbo Xu, Junhui Yi, Zhijian Yang, Xiong Deng, Yi Guo, Hao Deng

View Abstract ❯

Protein interacting with C‑kinase 1 modulates exocytosis and KATP conductance in pancreatic β cells

Yunhong Li, Fan Li, Bin Bai, Zhenyong Wu, Xiaolin Hou, Ying Shen, Yin Wang

View Abstract ❯

Isorhamnetin inhibits IL‑1β‑induced expression of inflammatory mediators in human chondrocytes

Jin Li, Ruishan Wu, Xiaoping Qin, Dongyang Liu, Fenjie Lin, Qinglu Feng

View Abstract ❯

Acute and chronic effects of taurine magnesium coordination compound on cardiac sodium channel Nav1.5

Lin Zhao, Xiao‑Xu Yang, Yong‑Qiang Yin, Hong Wu, Yi Kang, Jian‑Shi Lou

View Abstract ❯

Inhibitory effects of FKBP14 on human cervical cancer cells

Lian‑Yi Sun, Jiu‑Zhi Tao, Bing Yan, Jian‑Shu Lin

View Abstract ❯

Non-coding RNA 886 promotes renal cell carcinoma growth and metastasis through the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway

Jun Lei, Ju‑Hua Xiao, Shou‑Hua Zhang, Zhi‑Qiang Liu, Kai Huang, Zhi‑Peng Luo, Xin‑Lan Xiao, Zheng‑Dong Hong

View Abstract ❯

MicroRNA‑613 inhibits proliferation and invasion of renal cell carcinoma cells through targeting FZD7

Haitao Song, Yonghao Nan, Xinsheng Wang, Gang Zhang, Shi Zong, Xiangbo Kong

View Abstract ❯

Associations between mutations of the cell cycle checkpoint kinase 2 gene and gastric carcinogenesis

Yan Hong, Jun Shi, Zhijun Ge, Haorong Wu

View Abstract ❯

Upregulation of microRNA-25-3p inhibits proliferation, migration and invasion of osteosarcoma cells in vitro by directly targeting SOX4

Xiaolin Wu, Hongzhong Zhou, Bin Yue, Maohua Li, Fengxia Liu, Chensheng Qiu, Bohua Chen, Xuexiao Ma

View Abstract ❯

Metabolic characteristics of Rhizoma Coptidis intervention in spontaneously hypertensive rats: Insights gained from metabolomics analysis of serum

Wenqing Yang, Yue Deng, Honglei Zhou, Haiqiang Jiang, Yunlun Li, Yangjun Chu, Xiaoming Wang, Lili Gong

View Abstract ❯

Upregulation of nuclear factor‑κB and acid sensing ion channel 3 in dorsal root ganglion following application of nucleus pulposus onto the nerve root in rats

Dong Wang, Hao Pan, Hang Zhu, Li Zhu, Yong‑Jiang He, Jian Wang, Gao‑Yong Jia

View Abstract ❯

Curcumin prevents lipopolysaccharide-induced matrix metalloproteinase‑2 activity via the Ras/MEK1/2 signaling pathway in rat vascular smooth muscle cells

Yi Zhong, Jian Feng, Jiafu Li, Zhongcai Fan

View Abstract ❯

Investigation of the immunomodulatory activity of Tricholoma matsutake mycelium in cyclophosphamide-induced immunosuppressed mice

Quan Li, Yanzhen Wang, Yiling Chen, Meiyu Teng, Jian He, Xiaohan Wang, Fange Kong, Lirong Teng, Di Wang

View Abstract ❯

miR‑21 promotes α‑SMA and collagen I expression in hepatic stellate cells via the Smad7 signaling pathway

Rong‑Quan Fu, Dan‑Ping Hu, Yi‑Bing Hu, Liang Hong, Qing‑Feng Sun, Ji‑Guang Ding

View Abstract ❯

Hypotonic contrast media is more toxic than isotonic contrast media on endothelial cells in vivo and in vitro

Lihui Ren, Ping Wang, Zuoyan Wang, Yong Liu, Shuzheng Lv

View Abstract ❯

Follistatin-like protein 1 increases transepithelial resistance in kidney epithelial cells through Akt signaling

Fei Chen, Qiang Hu, Huihui Huang, Binbin Chen, Yin Xia, Wenjing Liu

View Abstract ❯

Downregulation of microRNA-143 promotes cell proliferation by regulating PKCε in hepatocellular carcinoma cells

Hanqiu Tang, Xiaotao Li, Rui Yang

View Abstract ❯

IL‑6/STAT3/miR‑34a protects against neonatal lung injury patients

Huajun Liu, Wenbin Liu, Xueqing Tang, Taisen Wang, Xianlin Sun, Jie Lv

View Abstract ❯

Anti‑inflammatory effects on murine macrophages of ethanol extracts of Lygodium japonicum spores via inhibition of NF‑κB and p38

Young‑Chang Cho, Ba Reum Kim, Hien Thi Thu Le, Sayeon Cho

View Abstract ❯

Implications of white matter damage in amyotrophic lateral sclerosis (Review)

Ting Zhou, Tina Khorshid Ahmad, Kiana Gozda, Jessica Truong, Jiming Kong, Michael Namaka

View Abstract ❯

Classical VEGF, Notch and Ang signalling in cancer angiogenesis, alternative approaches and future directions (Review)

Nunzia Caporarello, Gabriella Lupo, Melania Olivieri, Martina Cristaldi, Maria Teresa Cambria, Mario Salmeri, Carmelina Daniela Anfuso

View Abstract ❯

Role of the ACE2‑Ang‑(1‑7)‑Mas axis in blood pressure regulation and its potential as an antihypertensive in functional foods (Review)

Shiqi Lin, Huanglei Pan, Hongli Wu, Difeng Ren, Jun Lu

View Abstract ❯

Melatonin counteracts cobalt nanoparticle‑induced cytotoxicity and genotoxicity by deactivating reactive oxygen species‑dependent mechanisms in the NRK cell line

Yake Liu, Xiaoyou Yang, Wei Wang, Xuefei Wu, Hai Zhu, Fan Liu

View Abstract ❯

Anti-inflammatory effect of tribulusamide D isolated from Tribulus terrestris in lipopolysaccharide-stimulated RAW264.7 macrophages

Hyun Hwa Lee, Eun‑Kyung Ahn, Seong‑Su Hong, Joa Sub Oh

View Abstract ❯

Establishment of a murine pancreatic cancer pain model and microarray analysis of pain‑associated genes in the spinal cord dorsal horn

Liqin Wang, Huihong Xu, Yanhu Ge, Hai Zhu, Dawei Yu, Weifeng Yu, Zhijie Lu

View Abstract ❯

Histone demethylase PHF8 accelerates the progression of colorectal cancer and can be regulated by miR-488 in vitro

Yao Lv, Yan Shi, Quanli Han, Guanghai Dai

View Abstract ❯

Effects of combined general-epidural anesthesia and total intravenous anesthesia on cellular immunity and prognosis in patients with non‑small cell lung cancer: A comparative study

Qiang Xu, Nian‑Jun Shi, Hao Zhang, Yan‑Mei Zhu

View Abstract ❯

Curcumin attenuates the development of thoracic aortic aneurysm by inhibiting VEGF expression and inflammation

Xiang Li, Qin Fang, Xiaohong Tian, Xiaohong Wang, Qiang Ao, Weijian Hou, Hao Tong, Jun Fan, Shuling Bai

View Abstract ❯

Overexpression of long non-coding RNA differentiation antagonizing non-protein coding RNA inhibits the proliferation, migration and invasion and promotes apoptosis of renal cell carcinoma

Lu Jin, Huifang Fu, Jing Quan, Xiang Pan, Tao He, Jia Hu, Yifan Li, Hang Li, Yu Yang, Jing Ye, Fangting Zhang, Liangchao Ni, Shangqi Yang, Yongqing Lai

View Abstract ❯

Diverse gene expression patterns in response to anticancer drugs between human and mouse cell lines revealed by a comparative transcriptomic analysis

Yong Guo, Zhuoran Liang, Xiaoliang Hou, Zhi Zhang

View Abstract ❯

PCDH9 acts as a tumor suppressor inducing tumor cell arrest at G0/G1 phase and is frequently methylated in hepatocellular carcinoma

Jun Lv, Pengfei Zhu, Xiaolei Zhang, Ling Zhang, Xiangmei Chen, Fengmin Lu, Zujiang Yu, Shuang Liu

View Abstract ❯

Synergistic effects of fibroblast growth factor-2 and bone morphogenetic protein-2 on bone induction

Rongying Song, Dingding Wang, Rong Zeng, Ju Wang

View Abstract ❯

MRI detects protective effects of DAPT treatment with modulation of microglia/macrophages at subacute and chronic stages following cerebral ischemia

Xiao‑Zhu Hao, Jia‑Qi Tian, Le‑Kang Yin, Xiao‑Xue Zhang, Chan‑Chan Li, Xiao‑Yuan Feng, Zhen‑Wei Yao, Min Jiang, Yan‑Mei Yang

View Abstract ❯

MicroRNA-1291 promotes endometrial fibrosis by regulating the ArhGAP29-RhoA/ROCK1 signaling pathway in a murine model

Qian Xu, Hua Duan, Lu Gan, Xin Liu, Fang Chen, Xue Shen, Yi‑Qun Tang, Sha Wang

View Abstract ❯

T cell inhibition by pogostone from Pogostemon cablin (Blanco) Benth: In vitro and in vivo immunosuppressive analysis

Jiyan Su, Jingjin He, Ziren Su, Lian Zhou, Yaoying Zeng, Xiaoping Lai, Yucui Li

View Abstract ❯

Amyloid β-42 induces neuronal apoptosis by targeting mitochondria

Xiao‑Jian Han, Yang‑Yang Hu, Zhang‑Jian Yang, Li‑Ping Jiang, Sheng‑Lan Shi, Ye‑Ru Li, Miao‑Yu Guo, Hong‑Li Wu, Yu‑Ying Wan

View Abstract ❯

Time-series expression profile analysis of fracture healing in young and old mice

Chun Yuan, Jinfang Cai

View Abstract ❯

Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-β1

Peijin Shang, Tianlong Liu, Wenxing Liu, Yuwen Li, Fang Dou, Yikai Zhang, Lijuan Sun, Tiejun Zhang, Zhihui Zhu, Fei Mu, Yi Ding, Aidong Wen

View Abstract ❯

Lercanidipine attenuates angiotensin II-induced cardiomyocyte hypertrophy by blocking calcineurin-NFAT3 and CaMKII-HDAC4 signaling

Yuezhang Chen, Jie Yuan, Guoliang Jiang, Jianbing Zhu, Yunzeng Zou, Qianzhou Lv

View Abstract ❯

Influenza virus non‑structural protein 1 inhibits the production of interferon β of alveolar epithelial cells upon the infection of influenza A H1N1

Hao Jiang, Si‑Mei Shen, Jie Yin, Peng‑Peng Zhang, Yi Shi

View Abstract ❯

Molecular dynamics simulations of human E3 ubiquitin ligase Parkin

Shi Qiu, Shun Zhu, Shan Xu, Yanyan Han, Wen Liu, Ji Zuo

View Abstract ❯

Rab5a is overexpressed in oral cancer and promotes invasion through ERK/MMP signaling

Di Zhang, Changlong Lu, Hongjun Ai

View Abstract ❯

Grb2-associated binder 2 expression and its roles in uveal melanoma invasion

Meiling Chen, Yuehua Li, Xiuning Sun, Baogang Zhang, Wei Li, Shuxiao Wang, Xuetao Zhu, Feng Li, Lihong Shi

View Abstract ❯

Identification of the active compounds and significant pathways of yinchenhao decoction based on network pharmacology

Jihan Huang, Fan Cheung, Hor‑Yue Tan, Ming Hong, Ning Wang, Juan Yang, Yibin Feng, Qingshan Zheng

View Abstract ❯

CD147 blockade as a potential and novel treatment of graft rejection

Jing Luan, Yu Zhao, Yang Zhang, Jinlin Miao, Jia Li, Zhi‑Nan Chen, Ping Zhu

View Abstract ❯

PIM-1 kinase inhibitor SMI-4a exerts antitumor effects in chronic myeloid leukemia cells by enhancing the activity of glycogen synthase kinase 3β

Rui‑Fang Fan, Ying Lu, Zhi‑Gang Fang, Xiao‑Yan Guo, Yu‑Xin Chen, Yi‑Chuan Xu, Ya‑Mei Lei, Ke‑Fang Liu, Dong‑Jun Lin, Ling‑Ling Liu, Xiang‑Fu Liu

View Abstract ❯

TRPC1 stimulates calcium‑sensing receptor‑induced store‑operated Ca2+ entry and nitric oxide production in endothelial cells

Yuan‑Yuan Qu, La‑Mei Wang, Hua Zhong, Yong‑Min Liu, Na Tang, Li‑Ping Zhu, Fang He, Qing‑Hua Hu

View Abstract ❯

Downregulation of CCL2 induced by the upregulation of microRNA-206 is associated with the severity of HEV71 encephalitis

Guangyou Zhang, Jiwen Wang, Guo Yao, Baohai Shi

View Abstract ❯

Two novel cross‑protective antigens for bovine Pasteurella multocida

Huihui Du, Chenlu Wu, Chunming Li, Rendong Fang, Jianwei Ma, Jiale Ji, Zhihong Li, Nengzhang Li, Yuanyi Peng, Zeyang Zhou

View Abstract ❯

HPK1 positive expression associated with longer overall survival in patients with estrogen receptor-positive invasive ductal carcinoma‑not otherwise specified

Jiaojiao Wang, Lijie Song, Sen Yang, Weijie Zhang, Pengwei Lu, Shenglei Li, Huixiang Li, Liuxing Wang

View Abstract ❯

Naringenin attenuates fibroblast activation and inflammatory response in a mechanical stretch-induced hypertrophic scar mouse model

Shengzhou Shan, Yifan Zhang, Min Wu, Bo Yi, Jing Wang, Qingfeng Li

View Abstract ❯

Altered gene expression profile in a rat model of gentamicin-induced ototoxicity and nephrotoxicity, and the potential role of upregulated Ifi44 expression

Jun‑Gen Hu, Yu Fu, Jian‑Ju Xu, Xian‑Ping Ding, Hui‑Qi Xie, Jesse Li‑Ling

View Abstract ❯

MicroRNA-21 regulates the proliferation and apoptosis of cervical cancer cells via tumor necrosis factor-α

Lin Xu, Qian Xu, Xiwen Li, Xiaoling Zhang

View Abstract ❯

Abnormal expression of HAX‑1 is associated with cellular proliferation and migration in human hypopharyngeal squamous cell carcinoma

Hao Wu, Jianqiu Chen, Qiang Wang, Yong Yin, Peng Da, Huijun Le, Zhenxin Zhang, Xiaoxia Qiu

View Abstract ❯

Molecular mechanisms of breast cancer metastasis by gene expression profile analysis

Tianying Zheng, Aijun Wang, Dongyan Hu, Yonggang Wang

View Abstract ❯

Nerve growth factor pretreatment inhibits lidocaine‑induced myelin damage via increasing BDNF expression and inhibiting p38 mitogen activation in the rat spinal cord

Guangyi Zhao, Dan Li, Xudong Ding, Lu Li

View Abstract ❯

Identification of key genes and pathways associated with classical Hodgkin lymphoma by bioinformatics analysis

Zhixing Kuang, Li Guo, Xun Li

View Abstract ❯

Knockdown of lncRNA HNF1A-AS1 inhibits oncogenic phenotypes in colorectal carcinoma

Wenyi Zhu, Peipei Zhuang, Wen Song, Shiyu Duan, Qiong Xu, Man Peng, Jun Zhou

View Abstract ❯

Dysregulation of zinc/lipid metabolism‑associated genes in the rat hippocampus and cerebral cortex in early adulthood following recurrent neonatal seizures

Zhen‑Hong Li, Li‑Li Li, Mei‑Fang Jin, Xu‑Qin Chen, Qi Sun, Hong Ni

View Abstract ❯

Curcumin prevents reperfusion injury following ischemic stroke in rats via inhibition of NF‑κB, ICAM-1, MMP-9 and caspase-3 expression

Wei Li, Nijasri Charnnarong Suwanwela, Suthiluk Patumraj

View Abstract ❯

Identification of long non-coding RNA 00312 and 00673 in human NSCLC tissues

Qian Tan, Yalan Yu, Nandi Li, Wei Jing, Hu Zhou, Shili Qiu, Chunzi Liang, Mingxia Yu, Jiancheng Tu

View Abstract ❯

Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells

Chengjie Lian, Bo Gao, Zizhao Wu, Xianjian Qiu, Yan Peng, Anjing Liang, Caixia Xu, Peiqiang Su, Dongsheng Huang

View Abstract ❯

Construction of a recombinant pIRES2-EGFP-ARTS plasmid and its effect on LX-2 cells

Feifan Xu, Yuanlong Han, Dandan Zhu, Hua Tian, Huiming Zhu, Jingjing Ren, Delin Gu, Yinong Duan

View Abstract ❯

In vitro effects of Staphylococcus aureus enterotoxin C3 on T cell activation, proliferation and cytokine production

Yixin Xie, Min Wang, Zhihui Dong, Huan Song, Lianping Li, Min Yang, Pengling Li, Jingjing Tian, Kan Zhang, Xiaomeng Xia, Tingting Zhang, Aiguo Tang

View Abstract ❯

Bestrophin 1 gene analysis and associated clinical findings in a Chinese patient with Best vitelliform macular dystrophy

Ying Lin, Tao Li, Hongbin Gao, Yu Lian, Chuan Chen, Yi Zhu, Yonghao Li, Bingqian Liu, Wenli Zhou, Hongye Jiang, Xialin Liu, Xiujuan Zhao, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Lin Lu

View Abstract ❯

Atorvastatin increases Fads1, Fads2 and Elovl5 gene expression via the geranylgeranyl pyrophosphate-dependent Rho kinase pathway in 3T3-L1 cells

Noriko Ishihara, Sawako Suzuki, Shou Tanaka, Yasuhiro Watanabe, Daiji Nagayama, Atsuhito Saiki, Tomoaki Tanaka, Ichiro Tatsuno

View Abstract ❯

Differential expression of B-type natriuretic peptide between left and right ventricles, with particular regard to sudden cardiac death

Zhi‑Peng Cao, Jia‑Jia Xue, Yuan Zhang, Mei‑Hui Tian, Ying Xiao, Yu‑Qing Jia, Bao‑Li Zhu

View Abstract ❯

α7 nicotinic acetylcholine receptor agonist inhibits the damage of rat hippocampal neurons by TLR4/Myd88/NF‑κB signaling pathway during cardiopulmonary bypass

Keyan Chen, Yingjie Sun, Yugang Diao, Liu Ji, Dandan Song, Tiezheng Zhang

View Abstract ❯

TREM-2 negatively regulates LPS-mediated inflammatory response in rat bone marrow-derived MSCs

Pei Ye, Dawei Xu, Jinhuang Xu, Guiwang Liu, Shenghui Huang, Weiqiong Zhang, Peizhong Zheng, Jianhua Li, Jianrong Huang

View Abstract ❯

Individualized drug screening based on next generation sequencing and patient derived xenograft model for pancreatic cancer with bone metastasis

Zhonghai Guan, Huanrong Lan, Xiangheng Chen, Xiaoxia Jiang, Xuanwei Wang, Ketao Jin

View Abstract ❯

Protective effect of diminazene attenuates myocardial infarction in rats via increased inflammation and ACE2 activity

Junjiang Chen, Lianqun Cui, Jingliang Yuan, Songcun Zhang, Rongmei Ma, Hongjun Sang, Qingjiang Liu, Lianfeng Shan

View Abstract ❯

The impact of HuD protein on the intestinal nervous system in the terminal rectum of animal models of congenital anorectal malformation

Meng Kong, Yurui Wu, Yuanmei Liu

View Abstract ❯

Bioinformatic analysis of microRNA-mRNA expression profiles of bladder tissue induced by bladder outlet obstruction in a rat model

Liu Jian Duan, Qi Feng Cao, Ding Xu, Hai Long Liu, Jun Qi

View Abstract ❯

Disorder of the mevalonate pathway inhibits calcium-induced differentiation of keratinocytes

Rui Jin, Xin Luo, Kang Luan, Li Liu, Liang‑Dan Sun, Sen Yang, Sheng‑Quan Zhang, Xue‑Jun Zhang

View Abstract ❯

Beneficial effect of magnolol on lupus nephritis in MRL/lpr mice by attenuating the NLRP3 inflammasome and NF‑κB signaling pathway: A mechanistic analysis

Feng Huang, Rui‑Yun Zhang, Lei Song

View Abstract ❯

In silico design of colchicine-based bioisosteric inhibitors of tubulin for the treatment of rheumatoid arthritis

Li Wang, Hao‑Jie Yang, Ran Tu, Min Shen, Dan Liu

View Abstract ❯

MicroRNA-635 inhibits the malignancy of osteosarcoma by inducing apoptosis

Linqiang Tian, Zhihao Guo, Hongwei Wang, Xiaotan Liu

View Abstract ❯

Transcription of seven genes in a model of interferon‑γ-induced persistent Chlamydia psittaci infection

Zhixi Chen, Lili Chen, Chuan Wang, Jian Yu, Qinqin Bai, Minjun Yu, Yin Song, Yanqun Hu, Yimou Wu

View Abstract ❯

microRNA‑630 promotes cell proliferation and inhibits apoptosis in the HCT116 human colorectal cancer cell line

Lijuan Zhang, Gang Feng, Xinyan Zhang, Yawen Ding, Xiaojuan Wang

View Abstract ❯

PI3K/AKT signaling pathway activation in a rat model of migraine

Yun‑Yong Liu, Zi‑Yao Jiao, Wei Li, Qian Tian

View Abstract ❯

Reactive oxygen species modulator 1 regulates oxidative stress and induces renal and pulmonary fibrosis in a unilateral ureteral obstruction rat model and in HK‑2 cells

Donghai Liu, Ying Liu, Zhenkun Xia, Haiyun Dong, Zhuwen Yi

View Abstract ❯

miR-663 promotes NPC cell proliferation by directly targeting CDKN2A

Shaoqiang Liang, Ning Zhang, Yanming Deng, Lusi Chen, Yang Zhang, Zhenhe Zheng, Weijun Luo, Zhiqian Lv, Shaoen Li, Tao Xu

View Abstract ❯

Felodipine inhibits ox-LDL-induced reactive oxygen species production and inflammation in human umbilical vein endothelial cells

Jie Qi, Jian‑Bao Zheng, Wen‑Ting Ai, Xiao‑Wei Yao, Lei Liang, Gong Cheng, Xi‑Ling Shou, Chao‑Feng Sun

View Abstract ❯

Gold nanoparticles promote osteogenic differentiation of human periodontal ligament stem cells via the p38 MAPK signaling pathway

Chenguang Niu, Keyong Yuan, Rui Ma, Li Gao, Wenxin Jiang, Xuchen Hu, Wenzhen Lin, Xiaoling Zhang, Zhengwei Huang

View Abstract ❯

Long non‑coding RNA HOXA11‑AS promotes cell proliferation and metastasis in human breast cancer

Jian‑Chun Su, Xue‑Feng Hu

View Abstract ❯

Impacts of the serum containing total flavonoids of Ajuga on rat glomerular mesangial cells

Lihong Nan, Mei Huang, Wenfang Lai, Ru Jia, Yanfang Zheng, Lan Yang, Qingqing Xie, Weihua Peng

View Abstract ❯

Phylogenetic and specific sequence analysis of four paralogs in insect Aquaporins

Wei Xia, Panwen Zhao, Zhongquan Yi, Yubao Cui

View Abstract ❯

PEGylation of Lumbrokinase improves pharmacokinetic profile and enhances anti‑thrombotic effect in a rat carotid artery thrombosis model

Mingji Jin, Guangming Jin, Wei Huang, Zhonggao Gao

View Abstract ❯

Osthole protects against inflammation in a rat model of chronic kidney failure via suppression of nuclear factor-κB, transforming growth factor-β1 and activation of phosphoinositide 3-kinase/protein kinase B/nuclear factor (erythroid-derived 2)-like 2 signaling

Tao Huang, Zhen Dong

View Abstract ❯

Dioscin enhances osteoblastic cell differentiation and proliferation by inhibiting cell autophagy via the ASPP2/NF-κβ pathway

Chen Zhu, Nirong Bao, Shuo Chen, Jianning Zhao

View Abstract ❯

Curcumin analog EF24 induces apoptosis and downregulates the mitogen activated protein kinase/extracellular signal-regulated signaling pathway in oral squamous cell carcinoma

Chongxiang Lin, Chengwei Tu, Yike Ma, Pengcheng Ye, Xia Shao, Zhaoan Yang, Yiming Fang

View Abstract ❯

Elevated expression of yes‑associated protein is associated with the malignant status and prognosis of laryngeal squamous cell carcinoma

Chunchen Pan, Zhihui Du, Zhaogen Cai, Yun Liu, Yanbo Sun, Jin Chen, Ting Tong, Qingguo Chen, Liangqiang Zhou, Dan Bing, Yanling Tao, Hanqi Chu

View Abstract ❯

Ethanol extract of Antrodia camphorata inhibits proliferation of HCT-8 human colorectal cancer cells by arresting cell cycle progression and inducing apoptosis

Gong Wang, Yun Wan, Jinyan Zhao, Zhenfeng Hong

View Abstract ❯

Correlation analysis of surfactant protein A and surfactant protein D with lung function in exhaled breath condensate from lung cancer patients with and without COPD

Xuefeng Lin, Zhenlin Wu, Yichu Fan, Mingyou Chi, Xiaodong Wang, Xun Zhang, Daqiang Sun

View Abstract ❯

c‑Maf inducing protein inhibits cofilin‑1 activity and alters podocyte cytoskeleton organization

Lixia Yu, Jianming Ye, Qifeng Liu, Jianhua Feng, Xiaoxia Gu, Qiang Sun, Guoyuan Lu

View Abstract ❯

A20 protein regulates lipopolysaccharide-induced acute lung injury by downregulation of NF-κB and macrophage polarization in rats

Ying Wang, Zhenju Song, Jing Bi, Jie Liu, Lin Tong, Yuanlin Song, Chunxue Bai, Xiaodan Zhu

View Abstract ❯

Generation of a novel TRAIL mutant by proline to arginine substitution based on codon bias and its antitumor effects

Aijing Zhu, Xiuyun Wang, Min Huang, Chen Chen, Juan Yan, Qi Xu, Lijia Wei, Xianzhou Huang, Hong Zhu, Cheng Yi

View Abstract ❯

Knockdown of Hotair suppresses proliferation and cell cycle progression in hepatocellular carcinoma cell by downregulating CCND1 expression

Jia‑Jia Zhou, Di Cheng, Xiao‑Yu He, Zhe Meng, Wen‑Zhu Li, Ru‑Fu Chen

View Abstract ❯

Sigma-1 receptor activation ameliorates anxiety-like behavior through NR2A-CREB-BDNF signaling pathway in a rat model submitted to single-prolonged stress

Li‑Li Ji, Jun‑Bo Peng, Chang‑Hai Fu, Lei Tong, Zhen‑Yu Wang

View Abstract ❯

Danshensu attenuates aldosterone-induced cardiomyocytes injury through interfering p53 pathway

Xiaohong Yang, Rui Yang, Xianli Li, Xiaohui Zheng

View Abstract ❯

Stromal cell-derived factor 1 protects human periodontal ligament stem cells against hydrogen peroxide-induced apoptosis

Yimiao Feng, Xiaohui Fu, Xintian Lou, Baiping Fu

View Abstract ❯

MicroRNA-199b targets the regulation of ZEB1 expression to inhibit cell proliferation, migration and invasion in non‑small cell lung cancer

Jin Wang, Fachen Zhou, Liu Yin, Lei Zhao, Yixiang Zhang, Jinguang Wang

View Abstract ❯

SERCA1 attenuates diaphragm relaxation and uptake rate of SERCA in rats with acute sepsis

Jianyou Zhang, Hui Liu, Shitong Li, Jin Wu, Jianhong Sun

View Abstract ❯

Oncogenic miR-100-5p is associated with cellular viability, migration and apoptosis in renal cell carcinoma

Peijie Chen, Canbin Lin, Jing Quan, Yulin Lai, Tao He, Liang Zhou, Xiang Pan, Xueling Wu, Yong Wang, Liangchao Ni, Shangqi Yang, Tao Wang, Yongqing Lai

View Abstract ❯

E‑cadherin involvement in human lens epithelial cell transdifferentiation may be associated with N‑cadherin

Lei Huang, Jie Jiang, Qiang Guo, Hongbin Yang

View Abstract ❯

ILK promotes cell proliferation in breast cancer cells by activating the PI3K/Akt pathway

Yikun Qu, Chunfang Hao, Jian Xu, Zhuoxin Cheng, Weiqun Wang, Hong Liu

View Abstract ❯

Antidepressant-like effects of Marasmius androsaceus metabolic exopolysaccharides on chronic unpredictable mild stress-induced rat model

Jia Song, Xue Wang, Yu Huang, Yidi Qu, Lesheng Teng, Di Wang, Zhaoli Meng

View Abstract ❯

Oxidored-nitro domain-containing protein 1 promotes liver fibrosis by activating the Wnt/β-catenin signaling pathway in vitro

Tianxin Xiang, Shouhua Zhang, Na Cheng, Shanfei Ge, Jiangxiong Wen, Juhua Xiao, Xiaoping Wu

View Abstract ❯

MicroRNA‑744 inhibits tumor cell proliferation and invasion of gastric cancer via targeting brain‑derived neurotrophic factor

Ai‑Jun Xu, Li‑Na Fu, Hua‑Xing Wu, Xiao‑Li Yao, Rui Meng

View Abstract ❯

[Retracted] Effects of the eukaryotic initiation factor 6 gene on expression levels of inflammatory mediators in M2 macrophages during scar repair

Yong‑Qiang Bai, Jian‑Ke Feng, Qing‑Fu Zhang, Hong‑Zhi Wu, Ya‑Ru Du, Wei Wei

View Abstract ❯

Attention deficit hyperactivity disorder may be a highly inflammation and immune-associated disease (Review)

Rong‑Yi Zhou, Jiao‑Jiao Wang, Ji‑Chao Sun, Yue You, Jing‑Nang Ying, Xin‑Min Han

View Abstract ❯

Adhesion, proliferation and osteogenic differentiation of mesenchymal stem cells in 3D printed poly-ε-caprolactone/hydroxyapatite scaffolds combined with bone marrow clots

Pengfei Zheng, Qingqiang Yao, Fengyong Mao, Nancy Liu, Yan Xu, Bo Wei, Liming Wang

View Abstract ❯

Personalized identification of differentially expressed pathways in pediatric sepsis

Binjie Li, Qiyi Zeng

View Abstract ❯

Renal sympathetic denervation alleviates myocardial fibrosis following isoproterenol-induced heart failure

Neng Wang, Xiaoxin Zheng, Jin Qian, Wei Yao, Lu Bai, Guo Hou, Xuan Qiu, Xiaoyan Li, Xuejun Jiang

View Abstract ❯

A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Juhua Xiao, Qiang Tang, Huan Deng, Lu Chen

View Abstract ❯

Effect of RNA interference of the expression of HMGA2 on the proliferation and invasion ability of ACHN renal cell carcinoma cells

Ying Liu, Qi‑Zhong Fu, Lin Pu, Ling‑Ling Song, Yi‑Yun Wang, Jing Liu, Zhen‑Long Wang, Zi‑Ming Wang

View Abstract ❯

Identification of an lncRNA‑miRNA‑mRNA interaction mechanism in breast cancer based on bioinformatic analysis

Yuhan Zhang, Yongfeng Li, Qing Wang, Xiping Zhang, Dajin Wang, Hong Chao Tang, Xuli Meng, Xianfeng Ding

View Abstract ❯

Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis

Hongzhang Cui, Shu Li, Caiming Xu, Jingwen Zhang, Zhongwei Sun, Hailong Chen

View Abstract ❯

Microarray data re-annotation reveals specific lncRNAs and their potential functions in non-small cell lung cancer subtypes

Dongbo Zhou, Mingxuan Xie, Baimei He, Ying Gao, Qiao Yu, Bixiu He, Qiong Chen

View Abstract ❯

Regulatory effects and molecular mechanism of Trigonostemon reidioides on lipopolysaccharide‑induced inflammatory responses in RAW264.7 cells

Ju Young Shin, Jae‑Shin Kang, Hye‑Woo Byun, Eun‑Kyung Ahn

View Abstract ❯

Protective effects of Cervus nippon Temminck velvet antler polypeptides against MPP+‑induced cytotoxicity in SH‑SY5Y neuroblastoma cells

Ji‑Le Xin, Yang Zhang, Yan Li, Lian‑Zhu Zhang, Yong Lin, Lian‑Wen Zheng

View Abstract ❯

AKAP2 is upregulated in ovarian cancer, and promotes growth and migration of cancer cells

Xin Li, Changjun Wang, Gang Zhang, Ming Liang, Bin Zhang

View Abstract ❯

MicroRNA‑643 regulates the expression of ZEB1 and inhibits tumorigenesis in osteosarcoma

Huan Wang, Danmou Xing, Dong Ren, Wei Feng, Yan Chen, Zhiming Zhao, Zhihong Xiao, Zhengren Peng

View Abstract ❯

The effect of Bu Zhong Yi Qi decoction on simulated weightlessness‑induced muscle atrophy and its mechanisms

Mu Zhu, Zhongyang Liu, Mingze Gao, Yan Zhang, Yuheng Li, Shukuan Ling, Pengfei Zhang, Chenyang Zhao, Lijun Jiang, Yu Liu, Qi Li, Dong Li, Sumin Hu, Yingxian Li

View Abstract ❯

Expression of long non‑coding RNAs in chondrocytes from proximal interphalangeal joints

Dong Lv, Changzheng Su, Zhen Li, Xingyu Chai, Zhengwen Xu, Tao Pang

View Abstract ❯

FoxM1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by targeting Snai1

Chun‑Peng Yu, Shui Yu, Lei Shi, Song Wang, Zi‑Xiang Li, Yan‑Hua Wang, Cheng‑Jian Sun, Jun Liang

View Abstract ❯

Maternal diabetes impairs the initiation of meiosis in murine female germ cells

Xu‑Hua Qiu, Mei-Ling Li, Ng Li, Qin Sun, Ji Zhou, Ru‑Jun Ma, Ying Lin, Min Xie, Xie Ge, Li Chen, Bing Yao

View Abstract ❯

Zinc inhibits high glucose-induced NLRP3 inflammasome activation in human peritoneal mesothelial cells

Yi Fan, Xiuli Zhang, Lina Yang, Jun Wang, Ye Hu, Aishu Bian, Jin Liu, Jianfei Ma

View Abstract ❯

Human hepatocyte growth factor inhibits early neointima formation in rabbit abdominal aortae following ultrasound-guided balloon injury

Li Mei, Yu He, Hui Wang, Ying Jin, Shuai Wang, Chunxiang Jin

View Abstract ❯

Saponin extract from Panax notoginseng promotesangiogenesis through AMPK‑ and eNOS‑dependent pathways in HUVECs

Dongzhi Wang, Qiqiang Jie, Baoxin Liu, Yong Li, Liming Dai, Jiachen Luo, Lei Hou, Yidong Wei

View Abstract ❯

Tetrahydroxy stilbene glucoside ameliorates H2O2-induced human brain microvascular endothelial cell dysfunction in vitro by inhibiting oxidative stress and inflammatory responses

Zhao Jiang, Wenhong Wang, Chengcheng Guo

View Abstract ❯

Betaine attenuates chronic alcohol‑induced fatty liver by broadly regulating hepatic lipid metabolism

Wenjuan Yang, Luming Huang, Jinhang Gao, Shilei Wen, Yang Tai, Meng Chen, Zhiyin Huang, Rui Liu, Chengwei Tang, Jing Li

View Abstract ❯

Overexpression of long non-coding RNA cancer susceptibility 2 inhibits cell invasion and angiogenesis in gastric cancer

Jianfeng Zhou, Haiyan Huang, Shijie Tong, Rong Huo

View Abstract ❯

MicroRNA-130a is upregulated in colorectal cancer and promotes cell growth and motility by directly targeting forkhead box F2

Wenzhong Chen, Kehui Tong, Jiren Yu

View Abstract ❯

MicroRNA‑503 serves an oncogenic role in laryngeal squamous cell carcinoma via targeting programmed cell death protein 4

Yu Shuang, Xuan Zhou, Chao Li, Yongwang Huang, Lun Zhang

View Abstract ❯

Modulation of the immune response in rheumatoid arthritis with strategically released rapamycin

Ping Shao, Linxiao Ma, Yile Ren, Huijie Liu

View Abstract ❯

Sepsis decreases the activity of acetylcholinesterase by reducing its expression at the neuromuscular junction

Jin Wu, Tian Jin, Hong Wang, Shi‑Tong Li

View Abstract ❯

Licochalcone E protects against carbon tetrachloride‑induced liver toxicity by activating peroxisome proliferator-activated receptor gamma

Jichun Han, Dong Wang, Defang Li, Xiaoyu Chen, Bo Wang, Fenghua Wang, Xiaona Liu, Jing Shang, Qiusheng Zheng

View Abstract ❯

Effects of hydrogen sulfide on inducible nitric oxide synthase activity and expression of cardiomyocytes in diabetic rats

Rui Yang, Qiang Jia, Xiao‑Fen Liu, Yuan‑Yuan Wang, Shan‑Feng Ma

View Abstract ❯

Immunolocalization of cannabinoid receptor type 1 and CB2 cannabinoid receptors, and transient receptor potential vanilloid channels in pterygium

Martha Assimakopoulou, Dionysios Pagoulatos, Pinelopi Nterma, Nikolaos Pharmakakis

View Abstract ❯

Endothelial progenitor cell dysfunction in acute exacerbation of chronic obstructive pulmonary disease

Xiaoran Liu, Yangli Liu, Xinyan Huang, Gengpeng Lin, Canmao Xie

View Abstract ❯

Effects of Tribulus terrestris on monosodium iodoacetate‑induced osteoarthritis pain in rats

Young Jin Park, Young‑Rak Cho, Joa Sub Oh, Eun‑Kyung Ahn

View Abstract ❯

Personalized analysis of pathway aberrance induced by sevoflurane and propofol

Xianqiang Zheng, Jing Cong, Huidong Zhang, Xueliang Chu

View Abstract ❯

Hydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury

Da Li, Yanqiu Ai

View Abstract ❯

MicroRNA‑518b functions as a tumor suppressor in glioblastoma by targeting PDGFRB

Xiaolong Xu, Fenglin Zhang, Xianzhen Chen, Qi Ying

View Abstract ❯

C278F mutation in FGFR2 gene causes two different types of syndromic craniosynostosis in two Chinese patients

Ying Lin, Hongbin Gao, Siming Ai, Jacob V.P. Eswarakumar, Chuan Chen, Yi Zhu, Tao Li, Bingqian Liu, Xialin Liu, Lixia Luo, Hongye Jiang, Yonghao Li, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Lin Lu

View Abstract ❯

Sanggenon C protects against pressure overload‑induced cardiac hypertrophy via the calcineurin/NFAT2 pathway

Lili Xiao, Yulei Gu, Lu Gao, Jiahong Shangguan, Yang Chen, Yanzhou Zhang, Ling Li

View Abstract ❯

Methylation of mitochondrial DNA displacement loop region regulates mitochondrial copy number in colorectal cancer

Huan Tong, Linhao Zhang, Jinhang Gao, Shilei Wen, Hongying Zhou, Shi Feng

View Abstract ❯

Inhibitory effects of oxymatrine on TGF‑β1‑induced proliferation and abnormal differentiation in rat cardiac fibroblasts via the p38MAPK and ERK1/2 signaling pathways

Yini Xu, Hai Xiao, Hong Luo, Yan Chen, Yanyan Zhang, Ling Tao, Yan Jiang, Yuqi Chen, Xiangchun Shen

View Abstract ❯

Overexpressed microRNA-506 and microRNA-124 alleviate H2O2-induced human cardiomyocyte dysfunction by targeting krüppel-like factor 4/5

Xiuzhou Zhang, Fuyan Liu, Qingqing Wang, Yuxue Geng

View Abstract ❯

Quercetin alleviates generalized hyperalgesia in mice with induced adenomyosis

Jichan Nie, Xishi Liu

View Abstract ❯

Suppressive effects of human fetal keratinocytes on the proliferation, differentiation and extracellular matrix synthesis of human hypertrophic scar fibroblasts in vitro

Zhe Wang, Qibin Song, Hongqiu Li

View Abstract ❯

Proteomic profiling of human HepG2 cells treated with hesperidin using antibody array

Silvia Yumnam, Venu Venkatarame Gowda Saralamma, Suchismita Raha, Ho Jeong Lee, Won Sup Lee, Eun Kim Kim, Sang Joon Lee, Jeong Doo Heo, Gon Sup Kim

View Abstract ❯

Downregulation of miR‑136‑5p in hepatocellular carcinoma and its clinicopathological significance

Hua Ding, Zhi‑Hua Ye, Dong‑Yue Wen, Xiao‑Liang Huang, Chu‑Mei Zeng, Jie Mo, Yi‑Qiang Jiang, Jian‑Jun Li, Xiao‑Yong Cai, Hong Yang, Gang Chen

View Abstract ❯

Effect of varicocelectomy treatment on spermatogenesis and apoptosis via the induction of heat shock protein 70 in varicocele‑induced rats

Jin‑Zhuo Ning, Ting Rao, Fan Cheng, Wei‑Min Yu, Yuan Ruan, Run Yuan, Shao‑Ming Zhu, Yang Du, Cheng‑Cheng Xiao

View Abstract ❯

Analysis of intestinal microbial communities of cerebral infarction and ischemia patients based on high throughput sequencing technology and glucose and lipid metabolism

Wenzhen Ji, Yu Zhu, Pengcheng Kan, Ying Cai, Zhida Wang, Zijian Wu, Ping Yang

View Abstract ❯

PML(NLS¯) protein: A novel marker for the early diagnosis of acute promyelocytic leukemia

Zhi‑Ling Shan, Xin‑Yu Zhu, Peng‑Peng Ma, Hui Wang, Jianbin Chen, Jun Li, Liang Zhong, Bei‑Zhong Liu

View Abstract ❯

Comparative proteomic analysis of rats subjected to water immersion and restraint stress as an insight into gastric ulcers

Zheng‑Rong Zhou, Pan Huang, Guang‑Hao Song, Zhuang Zhang, Ke An, Han‑Wen Lu, Xiao‑Li Ju, Wei Ding

View Abstract ❯

Downregulation of microRNA-195 promotes angiogenesis induced by cerebral infarction via targeting VEGFA

Wen‑Jing Zhao, Hai‑Fang Zhang, Jin‑Ying Su

View Abstract ❯

Angelicin inhibits liver cancer growth in vitro and in vivo

Fengliang Wang, Jun Li, Rong Li, Guohua Pan, Mingxia Bai, Qiang Huang

View Abstract ❯

Significance of the TMPRSS2:ERG gene fusion in prostate cancer

Zhu Wang, Yuliang Wang, Jianwen Zhang, Qiyi Hu, Fan Zhi, Shengping Zhang, Dengqi Mao, Ying Zhang, Hui Liang

View Abstract ❯

Upregulation of ADAMTS‑7 and downregulation of COMP are associated with aortic aneurysm

Wei Qin, Yide Cao, Liangpeng Li, Wen Chen, Xin Chen

View Abstract ❯

Human papillomavirus E6-regulated microRNA-20b promotes invasion in cervical cancer by targeting tissue inhibitor of metalloproteinase 2

Yuan Cheng, Li Geng, Lijun Zhao, Peng Zuo, Jianliu Wang

View Abstract ❯

Autophagy may play an important role in varicocele

Shao‑Ming Zhu, Ting Rao, Xiao Yang, Jin‑Zhuo Ning, Wei‑Ming Yu, Yuan Ruan, Run Yuan, Cheng‑Long Li, Kun Jiang, Wei Hu, Hao‑Yong Li, Fan Cheng

View Abstract ❯

Plumbagin induces apoptosis in human osteosarcoma through ROS generation, endoplasmic reticulum stress and mitochondrial apoptosis pathway

Chia‑Chia Chao, Sheng‑Mou Hou, Chieh Chen Huang, Chun‑Han Hou, Po‑Chun Chen, Ju‑Fang Liu

View Abstract ❯

Long non-coding RNA Z38 promotes cell proliferation and metastasis in human renal cell carcinoma

Xiangfei He, Hongjun Liu, Fengfu Guo, Yanfei Feng, Yisheng Gao, Fuguang Sun, Bin Song, Hua Lu, Yang Li

View Abstract ❯

Clinicopathological analysis of 114 cases of typical Kaposi's sarcoma in Xinjiang Uygur autonomous region, China

Jun‑Wei Fan, Xue‑Feng Wan, Bian Yi, Jin‑Cheng Dong, Palida Abulize

View Abstract ❯

Knockdown of AQP1 inhibits growth and invasion of human ovarian cancer cells

Yanli Wang, Yanyan Fan, Chunhua Zheng, Xiaomeng Zhang

View Abstract ❯

Genome-wide DNA methylation analysis in permanent atrial fibrillation

Guochang Zhao, Jian Zhou, Jie Gao, Yan Liu, Song Gu, Xitao Zhang, Pixiong Su

View Abstract ❯

Hypoxia suppresses osteogenesis of bone mesenchymal stem cells via the extracellular signal‑regulated 1/2 and p38‑mitogen activated protein kinase signaling pathways

Peng Zhang, Nayoung Ha, Qinggang Dai, Siru Zhou, Chuangqi Yu, Lingyong Jiang

View Abstract ❯

Polaprezinc inhibits liver fibrosis and proliferation in hepatocellular carcinoma

Jun Ye, Zhengsen Zhang, Liang Zhu, Minfang Lu, Yan Li, Jingjing Zhou, Xinliang Lu, Qin Du

View Abstract ❯

Identification of a novel FOXL2 mutation in a single family with both types of blepharophimosis‑-ptosis-epicanthus inversus syndrome

Lin Yang, Tuo Li, Yiqiao Xing

View Abstract ❯

Polysaccharide purified from Lycium barbarum protects differentiated PC12 cells against L‑Glu‑induced toxicity via the mitochondria‑associated pathway

Ling Kou, Mingzhao Du, Chaopu Zhang, Zhiyin Dai, Xuan Li, Baohai Zhang, Xinyu Hu

View Abstract ❯

Human urine-derived stem cells contribute to the repair of ischemic acute kidney injury in rats

Shou‑Fu Tian, Zhen‑Zhen Jiang, Yu‑Mei Liu, Xin Niu, Bin Hu, Shang‑Chun Guo, Nian‑Song Wang, Yang Wang

View Abstract ❯

Toll‑like receptor 4 is expressed and functional in late endothelial progenitor cells

Min Yu, Cantian Wang, Guoning Zeng, Lihong Zhou, Tingting Chen, Xuerui Tan, Yanping Wang

View Abstract ❯

Effect of Scutellarin inhibits collagen‑induced arthritis through TLR4/NF‑κB‑mediated inflammation

Laibo Zhang, Shui Sun, Wei Li, Wei Zhang, Xianquan Wang, Shang-You Yang

View Abstract ❯

Cysteine-rich 61-associated gene expression profile alterations in human glioma cells

Rui Wang, Bo Wei, Jun Wei, Yu Tian, Chao Du

View Abstract ❯

miR-491-3p suppresses the growth and invasion of osteosarcoma cells by targeting TSPAN1

Junhu Duan, Jiangtao Liu, Yin Liu, Bin Huang, Longhua Rao

View Abstract ❯

Expression of microRNA‑222 in serum of patients with Alzheimer's disease

Qinghong Zeng, Linqing Zou, Li Qian, Fang Zhou, Hongxia Nie, Shanhua Yu, Jiandong Jiang, Aixia Zhuang, Chuanqi Wang, Haojiang Zhang

View Abstract ❯

Chinese herb extract improves liver steatosis by promoting the expression of high molecular weight adiponectin in NAFLD rats

Xudong Liu, Wangxia Tong, Xiaofang Zhao, Hongxing Zhang, Yanfang Tang, Xin Deng

View Abstract ❯

Long noncoding RNA colon cancer associated transcript‑1 promotes the proliferation, migration and invasion of cervical cancer

Ligang Jia, Yuan Zhang, Fei Tian, Zhaoping Chu, Hong Xin

View Abstract ❯

XB130 enhances invasion and migration of human colorectal cancer cells by promoting epithelial‑mesenchymal transition

Jiancheng Shen, Chang'e Jin, Yonglin Liu, Heping Rao, Jinrong Liu, Jie Li

View Abstract ❯

Identification of mutations in EXT1 and EXT2 genes in six Chinese families with multiple osteochondromas

Yang Xu, Qinglin Kang, Zhenlin Zhang

View Abstract ❯

Inhibitory effect of D3 dopamine receptors on neuropeptide Y‑induced migration in vascular smooth muscle cells

Xue‑Wei Xia, Yong‑Qiao Zhou, Hao Luo, Chunyu Zeng

View Abstract ❯

Inhibitory effect of curcumin in human endometriosis endometrial cells via downregulation of vascular endothelial growth factor

Hong Cao, Yu‑Xi Wei, Qi Zhou, Ying Zhang, Xiao‑Peng Guo, Jun Zhang

View Abstract ❯

Antimicrobial cathelicidin peptide LL‑37 induces NET formation and suppresses the inflammatory response in a mouse septic model

Hiroshi Hosoda, Kaho Nakamura, Zhongshuang Hu, Hiroshi Tamura, Johannes Reich, Kyoko Kuwahara‑Arai, Toshiaki Iba, Yoko Tabe, Isao Nagaoaka

View Abstract ❯

Ginkgolide B promotes cell growth in endothelial progenitor cells through miR-126 and the Akt signaling pathway

Jing Chang, Xin Xue, Chunli Song, Bin Liu, Lihua Gao

View Abstract ❯

Mda‑7/IL‑24 induces the differentiation of B cell lymphoma via activation of the P38 mitogen activated protein kinase signaling pathway

Ming Ma, Xingxiao Yang, Lianmei Zhao, Lihua Liu, Cong Zhang, Xuexiao Wang, Baoen Shan

View Abstract ❯

Expression of pro-inflammatory cytokines in the auditory cortex of rats with salicylate-induced tinnitus

Xiang‑Hong Chen, Li‑Li Zheng

View Abstract ❯

Transcriptional regulation and influence on replication of the human cytomegalovirus UL138 1.4 kb transcript

Liying Han, Yanping Ma, Zhongyang Liu, Chang Liu, Ying Lu, Ying Qi, Yujing Huang, Zhengrong Sun, Qiang Ruan

View Abstract ❯

Identification of key mRNAs and microRNAs in the pathogenesis and progression of osteoarthritis using microarray analysis

Hua Li, Bing Bai, Jingrui Wang, Zanmei Xu, Saiying Yan, Guobin Liu

View Abstract ❯

microRNA-20b contributes to high glucose-induced podocyte apoptosis by targeting SIRT7

Xiaojing Wang, Bo Lin, Lin Nie, Ping Li

View Abstract ❯

Dopamine and serotonin contribute to Paecilomyces hepiali against chronic unpredictable mild stress induced depressive behavior in Sprague Dawley rats

Juan Wang, Yange Liu, Lanzhou Li, Yidi Qi, Yuanzhu Zhang, Longtu Li, Lirong Teng, Di Wang

View Abstract ❯

Thy-1 stimulation of mouse T cells induces a delayed T cell receptor-like signal that results in Ca2+‑independent cytotoxicity

Suzanne Furlong, Melanie R. Power Coombs, David W. Hoskin

View Abstract ❯

FcγRIIb attenuates TLR4‑mediated NF‑κB signaling in B cells

Li Qian, Wenyan Chen, Shaoqing Wang, Yang Liu, Xiaoqin Jia, Yi Fu, Weijuan Gong, Fang Tian

View Abstract ❯

Ca2+/Mg2+ homeostasis‑related TRPM7 channel mediates chondrocyte hypertrophy via regulation of the PI3K‑Akt signaling pathway

Daigang Lu, Jining Qu, Liang Sun, Qiang Li, Hua Ling, Na Yang, Teng Ma, Qian Wang, Ming Li, Kun Zhang, Zhong Li

View Abstract ❯

MicroRNA‑320a inhibition decreases insulin‑induced KGN cell proliferation and apoptosis by targeting PCGF1

Lei Yang, Yan Li, Xiaojing Wang, Yuling Liu, Lingzhu Yang

View Abstract ❯

Overexpression of microRNA-448 inhibits osteosarcoma cell proliferation and invasion through targeting of astrocyte elevated gene-1

Weibo Jiang, Shu Wang, Yang Sun, Ying Jiang, Tao Yu, Jincheng Wang

View Abstract ❯

Direct and indirect gene diagnosis of hemophilia A pedigrees in the Chinese population

Ying Cao, Luxi Shen, Rong Huang, Lingcong Yang, Zhuanyun Du, Hua Ma, Tianjin Zheng, Haihua Gu, Hongzhi Li

View Abstract ❯

Type II cGMP‑dependent protein kinase inhibits the migration, invasion and proliferation of several types of human cancer cells

Min Wu, Yan Wu, Hai Qian, Yan Tao, Ji Pang, Ying Wang, Yongchang Chen

View Abstract ❯

[Corrigendum] Death receptor 5 expression is inversely correlated with prostate cancer progression

Angeles Hernandez‑Cueto, Daniel Hernandez‑Cueto, Gabriela Antonio‑Andres, Marisela Mendoza‑Marin, Carlos Jimenez‑Gutierrez, Ana Lilia Sandoval‑Mejia, Rosario Mora‑Campos, Cesar Gonzalez‑Bonilla, Mario I. Vega, Benjamin Bonavida, Sara Huerta‑Yepez

View Abstract ❯

5-7 October, 2017, Metropolitan Hotel, Athens, Greece

22nd World Congress on Advances in Oncology & 20th International Symposium on Molecular Medicine

3-4 October 2017, Pre-Congress Workshop:

'Next-Generation Sequencing – Library construction and quality control'

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