Scholar : Xenobiotica, Volume 47, Issue 12, December 2017 is now available online on Taylor & Francis Online

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The online platform for Taylor & Francis Online content Xenobiotica, Volume 47, Issue 12, December 2017 is now available online on Taylor & Francis Online. This new issue contains the following articles: General Xenobiochemistry In vitro metabolism of TAK-438, vonoprazan fumarate, a novel potassium-competitive acid blocker Hitomi Yamasaki, Naohiro Kawaguchi, Masami Nonaka, Junzo Takahashi, Akio Morohashi, Hideki Hirabayashi, Toshiya Moriwaki & Satoru Asahi Pages: 1027-1034 | DOI: 10.1080/00498254.2016.1203505 Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers Satish Kumar Bedada & Praveen Kumar Boga Pages: 1035-1041 | DOI: 10.1080/00498254.2016.1241450 Preclinical evaluation of the potential for cytochrome P450 inhibition and induction of the selective ALK inhibitor, alectinib Nobuo Sekiguchi, Shunsuke Nagao, Kenji Takanashi, Motohiro Kato, Akihisa Kaneko, Keiichi Morita, Hidetoshi Shindoh & Masaki Ishigai Pages: 1042-1051 | DOI: 10.1080/00498254.2016.1261308 Comparison of predictability for human pharmacokinetics parameters among monkeys, rats, and chimeric mice with humanised liver Maki Miyamoto, Shinji Iwasaki, Ikumi Chisaki, Sayaka Nakagawa, Nobuyuki Amano & Hideki Hirabayashi Pages: 1052-1063 | DOI: 10.1080/00498254.2016.1265160 Clinical Pharmacokinetics and Metabolism Metabolism, excretion and pharmacokinetics of [14C]glasdegib (PF-04449913) in healthy volunteers following oral administration Justine L. Lam, Alfin Vaz, Brian Hee, Yali Liang, Xin Yang & M. Naveed Shaik Pages: 1064-1076 | DOI: 10.1080/00498254.2016.1261307 Pradigastat disposition in humans: in vivo and in vitro investigations Alana Upthagrove, Jin Chen, Charles D. Meyers, Kenneth Kulmatycki, Angela Bretz, Lai Wang, Lana Peng, Safet Palamar, Melissa Lin, Tapan Majumdar, Phi Tran & Heidi J. Einolf Pages: 1077-1089 | DOI: 10.1080/00498254.2016.1263405 Animal Pharmacokinetics and Metabolism Pharmacokinetics, distribution, and disposition of esaxerenone, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist, in rats and monkeys Makiko Yamada, Makoto Takei, Eiko Suzuki, Hideo Takakusa, Masakatsu Kotsuma, Takuo Washio, Nobuyuki Murayama, Shin-ichi Inoue & Takashi Izumi Pages: 1090-1103 | DOI: 10.1080/00498254.2016.1263766 Oral pharmacokinetic interaction of ester rich fruit juices and pharmaceutical excipients with tenofovir disoproxil fumarate in male Wistar rats Joseph Shailender, Punna Rao Ravi, Paramita Saha & Srividya Myneni Pages: 1104-1111 | DOI: 10.1080/00498254.2016.1269375 Xenobiotic transporters Potent inhibition of human organic cation transporter 2 (hOCT2) by β-carboline alkaloids David J. Wagner, Haichuan Duan, Alenka Chapron, Richard W. Lee & Joanne Wang Pages: 1112-1120 | DOI: 10.1080/00498254.2016.1271160 Pharmacogenetics Effects of cytochrome P450 3A4 and non-genetic factors on initial voriconazole serum trough concentrations in hematological patients with different cytochrome P450 2C19 genotypes Beibei Shao, Yongcheng Ma, Qiaoyan Li, Yimeng Wang, Zunmin Zhu, Hongwei Zhao, Jun Sun, Lingfang Dong, Yingli Zhu, Ningmin Zhao & Yuhua Qin Pages: 1121-1129 | DOI: 10.1080/00498254.2016.1271960 Association of PEAR1 rs12041331 polymorphism and pharmacodynamics of ticagrelor in healthy Chinese volunteers Mupeng Li, Yaodong Hu, Zhipeng Wen, Huilan Li, Xiaolei Hu, Yanjiao Zhang, Zanling Zhang, Jian Xiao, Jie Tang & Xiaoping Chen Pages: 1130-1138 | DOI: 10.1080/00498254.2016.1271962 Editorial Board Editorial Board Pages: ebi-ebi | DOI: 10.1080/00498254.2017.1394548 To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.