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Σάββατο 23 Δεκεμβρίου 2017

Predictive value of EEG for febrile seizure recurrence

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Publication date: Available online 23 December 2017
Source:Brain and Development
Author(s): Alberto M. Cappellari, Carolina Brizio, Marta B. Mazzoni, Giuseppe Bertolozzi, Federica Vianello, Alessia Rocchi, Massimo Belli, Andrea Nossa, Dario Consonni, Gregorio P. Milani, Emilio F. Fossali
ObjectiveTo define the role of the EEG in predicting recurrence of febrile seizures (FS) in children after a first FS.MethodsChildren with a first simple or complex FS who underwent EEG at our hospital were retrospectively enrolled. EEG recordings were classified in three groups: normal, abnormal (slow activity or epileptiform discharges), and pseudo-petit mal discharge (PPMD) pattern. Children were followed-up for at least three years.ResultsA total of 126 patients met the entry criteria, and 113 of them completed the follow-up. Risk of FS recurrence decreased linearly with increasing age (−2% per month). The risk was higher among patients with PPMD pattern (absolute risk 86%, adjusted relative risk 2.00) and abnormal EEG (epileptiform discharges: absolute risk 71%, adjusted relative risk 2.00; slow activity: absolute risk 56%, adjusted relative risk 1.44), compared with those with normal EEG (absolute risk 41%).ConclusionsPPMD and abnormal EEG should be considered as an independent risk factor for FS recurrence.



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