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Σάββατο 23 Δεκεμβρίου 2017

Scholar : Xenobiotica, Volume 48, Issue 2, February 2018 is now available online on Taylor & Francis Online

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Xenobiotica, Volume 48, Issue 2, February 2018 is now available online on Taylor & Francis Online.



This new issue contains the following articles:

General Xenobiochemistry

Identification and characterization of human UDP-glucuronosyltransferases responsible for xanthotoxol glucuronidation
Guiyuan He, Johanna Troberg, Xia Lv, Yang-Liu Xia, Liang-Liang Zhu, Jing Ning, Guang-Bo Ge, Moshe Finel & Ling Yang
Pages: 109-116 | DOI: 10.1080/00498254.2017.1283719


Human plasma metabolic profiles of benzydamine, a flavin-containing monooxygenase probe substrate, simulated with pharmacokinetic data from control and humanized-liver mice
Miho Yamazaki-Nishioka, Makiko Shimizu, Hiroshi Suemizu, Megumi Nishiwaki, Marina Mitsui & Hiroshi Yamazaki
Pages: 117-123 | DOI: 10.1080/00498254.2017.1288280


Dimethylarsinic acid modulates the aryl hydrocarbon receptor-regulated genes in C57BL/6 mice: in vivo study
Osama H. Elshenawy, Ghada Abdelhamid, Hassan N. Althurwi & Ayman O. S. El-Kadi
Pages: 124-134 | DOI: 10.1080/00498254.2017.1289423


Predictions of bisphenol A hepatic clearance in the isolated perfused rat liver (IPRL): impact of albumin binding and of co-administration with naproxen
Sara Bounakta, Michel Bteich, Marc Mantha, Patrick Poulin & Sami Haddad
Pages: 135-147 | DOI: 10.1080/00498254.2017.1294276


Area under the curve predictions of dalbavancin, a new lipoglycopeptide agent, using the end of intravenous infusion concentration data point by regression analyses such as linear, log-linear and power models
Ravi Kanth Bhamidipati, Muzeeb Syed, Ramesh Mullangi & Nuggehally Srinivas
Pages: 148-156 | DOI: 10.1080/00498254.2017.1294278


Animal Pharmacokinetics and Metabolism

Metabolism of metofluthrin in rats: I. Identification of metabolites
Jun Abe, Hirohisa Nagahori, Hirokazu Tarui, Yoshitaka Tomigahara & Naohiko Isobe
Pages: 157-169 | DOI: 10.1080/00498254.2017.1283718


Aldehyde oxidase-dependent species difference in hepatic metabolism of fasudil to hydroxyfasudil
Zhengsheng Mao, Yali Wu, Qiuying Li, Xin Wang, Youping Liu & Xin Di
Pages: 170-177 | DOI: 10.1080/00498254.2017.1292016


Effect of piperine on the bioavailability and pharmacokinetics of rosmarinic acid in rat plasma using UPLC-MS/MS
Jun-Hui Yang, Kun-Jun Mao, Ping Huang, Yin-Jun Ye, Hua-Shan Guo & Bao-Chang Cai
Pages: 178-185 | DOI: 10.1080/00498254.2017.1292564


Pharmacokinetics of the selective prostacyclin receptor agonist selexipag in rats, dogs and monkeys
Tomohiko Ichikawa, Tetsuhiro Yamada, Alexander Treiber, Carmela Gnerre & Kiyoko Nonaka
Pages: 186-196 | DOI: 10.1080/00498254.2017.1294277


Xenobiotic Transporters

The inhibitory effects of five alkaloids on the substrate transport mediated through human organic anion and cation transporters
Tahiatul Shams, Xiaoxi Lu, Ling Zhu & Fanfan Zhou
Pages: 197-205 | DOI: 10.1080/00498254.2017.1282647


Pharmacogenetics

R-warfarin clearances from plasma associated with polymorphic cytochrome P450 2C19 and simulated by individual physiologically based pharmacokinetic models for 11 cynomolgus monkeys
Masahiro Utoh, Takashi Kusama, Tomonori Miura, Marina Mitsui, Mirai Kawano, Takahiro Hirano, Makiko Shimizu, Yasuhiro Uno & Hiroshi Yamazaki
Pages: 206-210 | DOI: 10.1080/00498254.2017.1288945


Topics in Xenobiochemistry

Xenobiotic C-sulfonate derivatives; metabolites or metabonates?
Stephen C. Mitchell
Pages: 211-218 | DOI: 10.1080/00498254.2017.1292565


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