Apoptotic Regulatory T Cells Retain Suppressive Function through Adenosine

Publication date: 9 January 2018
Source:Cell Metabolism, Volume 27, Issue 1
Author(s): Ulf H. Beier
Regulatory T cells maintain tolerance and prevent autoimmunity, but their suppressive effects can hinder immune responses against cancer. In Nature Immunology, Maj et al., 2017 report that regulatory T cells can execute these actions through the nucleoside adenosine even after cell death.

Teaser

Regulatory T cells maintain tolerance and prevent autoimmunity, but their suppressive effects can hinder immune responses against cancer. In Nature Immunology, Maj et al., 2017 report that regulatory T cells can execute these actions through the nucleoside adenosine even after cell death.


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