A multicenter pilot study on the indications of the negative pressure sleep therapy system for the treatment of obstructive sleep apnea
CM Lin, LW Hang, KT Chou, TJ Liu, C Guilleminault - Sleep Medicine, 2017
Materials and methods: The iNAP® was designed to decrease airway obstruction by forming
negative pressure within the confined space in the oral cavity and stabilizing the soft tissues
around pharynx, thereby preventing sleep-disordered breathing for obstructive sleep apnea
negative pressure within the confined space in the oral cavity and stabilizing the soft tissues
around pharynx, thereby preventing sleep-disordered breathing for obstructive sleep apnea
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Factors influencing compliance to continuous positive airway pressure treatment in obstructive sleep apnea and mortality associated with treatment failure
A Palm, B Midgren, J Theorell-Haglöw, C Janson… - Sleep Medicine, 2017
Methods: Data derived from the Swedish quality registry Swedevox on patients starting
treatment with CPAP due to OSA between 1 July 2010 and 31 December 2016 and follow-
up data until 10 Mars 2017 were analysed. Information about compliance to CPAP treatment
treatment with CPAP due to OSA between 1 July 2010 and 31 December 2016 and follow-
up data until 10 Mars 2017 were analysed. Information about compliance to CPAP treatment
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CPAP withdrawal on 24-hour blood pressure and arterial stiffness in women and men with obstructive sleep apnea. A randomized controlled trial
C Sahlin, A Blomberg, KA Franklin - Sleep Medicine, 2017
Materials and methods: One hundred CPAP treated patients with moderate and severe
sleep apnea were randomized to either withdrawal treatment for 5 days (n= 50) or to
continue with CPAP for 5 days (n= 50). 24-hours blood pressure, arterial stiffness measured
sleep apnea were randomized to either withdrawal treatment for 5 days (n= 50) or to
continue with CPAP for 5 days (n= 50). 24-hours blood pressure, arterial stiffness measured
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… (pharmacotherapy of apnea by cannabimimetic enhancement) clinical trial: characteristics of clinical responders to dronabinol treatment of obstructive sleep apnea
DW Carley, B Prasad, KJ Reid, R Malkani, H Attarian… - Sleep Medicine, 2017
Materials and methods: By random assignment, 73 adults with moderate-to-severe OSA
received either placebo (N= 25), 2.5 mg dronabinol (N= 21) or 10 mg dronabinol (N= 27)
daily, one hour before bedtime for up to 6 weeks. Each subject completed laboratory
received either placebo (N= 25), 2.5 mg dronabinol (N= 21) or 10 mg dronabinol (N= 27)
daily, one hour before bedtime for up to 6 weeks. Each subject completed laboratory
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A comparison of upper airway patency by dexmedetomidine and propofol used for intraoperative sedation in patients with obstructive sleep apnea
BW Goo, IS Park, EY Kim, HJ Shin, SH Do, HS Na - Sleep Medicine, 2017
Background: Sedation state by dexmedetomidine is known to be similar with physiologic
sleep status, and respiratory depression was observed less frequently. On the other hand,
sedation by propofol can cause respiratory depression, even though it has advantages of
sleep status, and respiratory depression was observed less frequently. On the other hand,
sedation by propofol can cause respiratory depression, even though it has advantages of
| | |
… -blind, multicenter, 12-week study of the safety and efficacy of solriamfetol (JZP-110) for the treatment of excessive sleepiness in patients with obstructive sleep apnea
C Drake, R Bogan, H Benes, T Stern, KF Villa, D Chen… - Sleep Medicine, 2017
Methods: Eligibility criteria: OSA diagnosis per International Classification of Sleep
Disorders-3; past or present use of primary OSA therapy; Epworth Sleepiness Scale score≥
10; mean sleep latency< 30 minutes on first 4 trials of a 5-trial, 40-minute Maintenance of
Disorders-3; past or present use of primary OSA therapy; Epworth Sleepiness Scale score≥
10; mean sleep latency< 30 minutes on first 4 trials of a 5-trial, 40-minute Maintenance of
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Autonomic nervous system responses to autonomic challenges in upper airway resistance syndrome patients differ from obstructive sleep apnea
L Godoy, L Palombini, C Rizzi, L Otuyama, J Colombo… - Sleep Medicine, 2017
Materials and methods: Forty patients were studied: 20 UARS and 20 moderate-to-severe
OSA (AHI> 20 events/hour) patients matched for age and gender. UARS criteria were
presence of sleepiness (Epworth Sleepiness Scale≥ 10) and/or fatigue (Modified Fatigue
OSA (AHI> 20 events/hour) patients matched for age and gender. UARS criteria were
presence of sleepiness (Epworth Sleepiness Scale≥ 10) and/or fatigue (Modified Fatigue
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Validity and cost-efectiviness analysis of pediatric home respiratory poligraphy for the diagnosis of obstructive sleep apnea: rationale, design, and methodology
…, MA Villar, D Gozal, Spanish Sleep Network - Sleep Medicine, 2017
Introduction: Obstructive sleep apnea (OSA) in children is a highly prevalent condition associated
with neurobehavioral, cardiovascular, and metabolic morbidities. However, most of children with
OSA remain undiagnosed. Diagnosis of OSA requires conventional polysomnography
with neurobehavioral, cardiovascular, and metabolic morbidities. However, most of children with
OSA remain undiagnosed. Diagnosis of OSA requires conventional polysomnography
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Urinary proteins as potential biomarkers for adult patients with obstructive sleep apnea
M Kohli, SK Sharma, S Sengupta - Sleep Medicine, 2017
Materials and methods: Early morning blood and urine samples were collected from
subjects confirmed to be OSA or non-OSA subjects by polysomnography. The study was
carried out using proteomics approach in three phases; i) identification phase; ii) verification
subjects confirmed to be OSA or non-OSA subjects by polysomnography. The study was
carried out using proteomics approach in three phases; i) identification phase; ii) verification
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Psychological evaluation of patients scheduled for maxillomandibular advancement as a treatment for obstructive sleep apnea: preliminary report
T Provenzano, P Pozzi, A Ambrosoli, L Levrini… - Sleep Medicine, 2017
Materials and Methods: A personality exhamination through the Hospital Anxiety and
Depression Scale (HADS-A; HADS-D) and the Rorschach Inkblot Method (RIM). Results:
The mean apnea-hypopnea index at baseline was 46.2+ 18.8 events/hour. A high
Depression Scale (HADS-A; HADS-D) and the Rorschach Inkblot Method (RIM). Results:
The mean apnea-hypopnea index at baseline was 46.2+ 18.8 events/hour. A high
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