Illuminating GPCR Signaling by Cryo-EM

Publication date: Available online 23 June 2018
Source:Trends in Cell Biology
Author(s): Haaris Ahsan Safdari, Shubhi Pandey, Arun K. Shukla, Somnath Dutta
The wave of resolution revolution in cryo-EM has touched, and made a significant impact on, the structural biology of GPCRs. High-resolution structures of several GPCR-G-protein complexes are now determined by cryo-EM and they illuminate fine structural details of this central macromolecular complex involved in cellular signaling.



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