Yeast and Human Nuclear Pore Complexes: Not So Similar After All

Publication date: Available online 22 June 2018
Source:Trends in Cell Biology
Author(s): Yaron Shav-Tal, Timir Tripathi
Nucleoporin subunits that generate the nuclear pore complex (NPC) are highly conserved in evolution. High-resolution structures of the NPC are available, but the actual NPC composition in yeast has only been quantified recently. Two studies reveal major differences between species, suggesting high flexibility in NPC structures during evolution.



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